Safety and role of ketogenic parenteral nutrition for intractable childhood epilepsy

Brain and Development

Volumn 34, Issue 8, 2012, Pages 620-624

  Jung, Da Eun ^a   Kang, Hoon Chul ^b   Lee, Joon Soo ^b   Lee, Eun Joo ^b   Kim, Heung Dong ^b  

^a Ajou University School of Medicine   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

Intractable childhood epilepsy; Ketogenic parenteral nutrition

Indexed keywords

ALANINE AMINOTRANSFERASE; AMYLASE; ASPARTATE AMINOTRANSFERASE; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BENIGN CHILDHOOD EPILEPSY; CHILD; CHROMOSOME 13; CHROMOSOME ABERRATION; CLINICAL ARTICLE; COMORBIDITY; DEVELOPMENTAL DISORDER; DIARRHEA; DISEASE CONTROL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EVALUATION AND FOLLOW UP; FEMALE; HUMAN; HYPERLIPIDEMIA; HYPOXIC ISCHEMIC ENCEPHALOPATHY; INFANT; INFANTILE SPASM; KETOACIDOSIS; KETOGENIC DIET; LENNOX GASTAUT SYNDROME; MALE; NUTRIENT UPTAKE; NUTRITIONAL ASSESSMENT; NUTRITIONAL HEALTH; NUTRITIONAL SUPPORT; ONSET AGE; PANCREATITIS; PARENTERAL NUTRITION; RETT SYNDROME; SAFETY; SEVERE MYOCLONIC EPILEPSY IN INFANCY; TREATMENT DURATION; VOMITING;

CHILD; CHILD, PRESCHOOL; EPILEPSY; FEMALE; GASTROINTESTINAL DISEASES; HUMANS; INFANT; KETOGENIC DIET; MALE; PARENTERAL NUTRITION; RETROSPECTIVE STUDIES;

EID: 84864739559     PISSN: 03877604     EISSN: 18727131     Source Type: Journal    
DOI: 10.1016/j.braindev.2011.11.008     Document Type: Article

References (11)

1. Freeman J., Veggiotti P., Lanzi G., Tagliabue A., Perucca E. The KD: From molecular mechanisms to clinical effects. Epilepsy Res 2006, 68:145-180.
2. Rosenthal E., Weissman B., Kyllonen K. Use of parenteral medium-chain triglyceride emulsion for maintaining seizure control in a 5-year-old girl with intractable diarrhea. JPEN J Parenter Enteral Nutr 1990, 14:543-545.
3. Kang H.C., Chung D.E., Kim D.W., Kim H.D. Early- and late-onset complications of the ketogenic diet for intractable epilepsy. Epilepsia 2004, 45:1116-1123.
4. Jung da E., Chung J.Y., Kang H.C., Kim H.D. Improving tolerability of the ketogenic diet in patients with abnormal endoscopic findings. Brain Dev 2008, 30:416-419.
5. Stewart W.A., Gordon K., Camfield P. Acute pancreatitis causing death in a child on the ketogenic diet. J Child Neurol 2001, 16:682.
6. Btaiche I.F., Khalidi N. Parenteral nutrition-associated liver complications in children. Pharmacotherapy 2002, 22:188-211.
7. Krohn K., Koletzko B. Parenteral lipid emulsions in paediatrics. Curr Opin Clin Nutr Metab Care 2006, 9:319-323.
8. Wheless J.W., Ashwal S. The ketogenic diet. Pediatric neurology: principles & practice 1999, 719-728. Mosby, Missouri. 3rd ed. K.F. Swaiman (Ed.).
9. Huttenlocher P.R., Wilbourn A.J., Signore J.M. Medium-chain triglycerides as a therapy for intractable childhood epilepsy. Neurology 1971, 21:1097-1103.
10. Schwartz R.H., Eaton J., Bower B.D., Aynsley-Green A. Ketogenic diets in the treatment of epilepsy: short-term clinical effects. Dev Med Child Neurol 1989, 31:145-151.
11. Neal E.G., Chaffe H.M., Edwards N., Lawson M.S., Schwartz R.H., Cross J.H. Growth of children on classical and medium-chain triglyceride ketogenic diets. Pediatrics 2008, 122:e334-e340.