Prediction of the histopathological grade of hepatocellular carcinoma using qualitative diffusion-weighted, dynamic, and hepatobiliary phase MRI

European Radiology

Volumn 22, Issue 8, 2012, Pages 1701-1708

  An, Chansik ^a   Park, Mi Suk ^a,b   Jeon, Hyae Min ^b   Jeon, Yeo Eunc ^a   Chung, Woo Suk ^a   Chung, Yong Eun ^a   Kim, Myeong Jin ^a,b   Kim, Ki Whang ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Yonsei University   (South Korea)

Author keywords

Diffusion weighted MRI; Gd EOB DTPA; Hepatocellular carcinoma; Subtraction technique; Tumor grading

Indexed keywords

GADOXETIC ACID;

ADULT; AGED; ARTICLE; CANCER GRADING; DIFFUSION WEIGHTED IMAGING; DYNAMIC SUBTRACTION IMAGING; FEMALE; HEPATOBILIARY RADIOGRAPHY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PREDICTIVE VALUE; PRIORITY JOURNAL;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; DIFFUSION; DIFFUSION MAGNETIC RESONANCE IMAGING; FEMALE; GADOLINIUM DTPA; HEPATOCYTES; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LIVER NEOPLASMS; MALE; MIDDLE AGED; OBSERVER VARIATION; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; SUBTRACTION TECHNIQUE;

EID: 84864714891     PISSN: 09387994     EISSN: 14321084     Source Type: Journal    
DOI: 10.1007/s00330-012-2421-6     Document Type: Article

References (19)

1. Jonas S, Bechstein WO, Steinmuller T et al (2001) Vascular invasion and histopathologic grading determine outcome after liver transplantation for hepatocellular carcinoma in cirrhosis. Hepatology 33:1080-1086
2. Ker CG, Chen HY, Chen KS et al (2003) Clinical significance of cell differentiation in hepatocellular carcinoma. Hepatogastroenterology 50:475-479
3. Ariizumi S, Takasaki K, Yamamoto M, Ohtsubo T, Katsuragawa H, Katagiri S (2004) Histopathologic differentiation of the main nodule determines outcome after hepatic resection for synchronous multicentric hepatocellular carcinomas. Hepatogastroenterology 51:500-504
4. Prez-Saborido B, de los Galanes SJ, Menu-Daz JC et al (2007) Tumor recurrence after liver transplantation for hepatocellular carcinoma: recurrence pathway and prognostic factors. Transplant Proc 39:2304-2307
5. Haratake J, Takeda S, Kasai T, Nakano S, Tokui N (1993) Predictable factors for estimating prognosis of patients after resection of hepatocellular carcinoma. Cancer 72:1178-1183
6. Okusaka T, Okada S, Ueno H et al (2002) Satellite lesions in patients with small hepatocellular carcinoma with reference to clinicopathologic features. Cancer 95:1931-1937
7. Oishi K, Itamoto T, Amano H et al (2007) Clinicopathologic features of poorly differentiated hepatocellular carcinoma. J Surg Oncol 95:311-316
8. Kogita S, Imai Y, Okada M et al Gd-EOB-DTPA-enhanced magnetic resonance images of hepatocellular carcinoma: correlation with histological grading and portal blood flow. Eur Radiol 20:2405-2413
9. Nishie A, Tajima T, Asayama Y et al (2010) Diagnostic performance of apparent diffusion coefficient for predicting histological grade of hepatocellular carcinoma. Eur J Radiol 80:e29-e33
10. Nasu K, Kuroki Y, Tsukamoto T, Nakajima H, Mori K, Minami M (2009) Diffusion-weighted imaging of surgically resected hepatocellular carcinoma: imaging characteristics and relationship among signal intensity, apparent diffusion coefficient, and histopathologic grade. AJR Am J Roentgenol 193:438-444
11. Heo SH, Jeong YY, Shin SS et al (2010) Apparent diffusion coefficient value of diffusion-weighted imaging for hepatocellular carcinoma: correlation with the histologic differentiation and the expression of vascular endothelial growth factor. Korean J Radiol 11:295-303
12. Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A (2009) AJCC cancer staging manual, 7th edn. Springer, New York
13. Mazzaferro V, Regalia E, Doci R et al (1996) Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 334:693-699
14. Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159-174
15. Muhi A, Ichikawa T, Motosugi U et al (2009) High-b-value diffusion-weighted MR imaging of hepatocellular lesions: estimation of grade of malignancy of hepatocellular carcinoma. J Magn Reson Imaging 30:1005-1011
16. Yu JS, Kim YH, Rofsky NM (2005) Dynamic subtraction magnetic resonance imaging of cirrhotic liver: assessment of high signal intensity lesions on nonenhanced T1-weighted images. J Comput Assist Tomogr 29:51-58
17. Secil M, Obuz F, Altay C et al (2008) The role of dynamic subtraction MRI in detection of hepatocellular carcinoma. Diagn Interv Radiol 14:200-204
18. Asayama Y, Yoshimitsu K, Nishihara Yet al (2008) Arterial blood supply of hepatocellular carcinoma and histologic grading: radiologic-pathologic correlation. AJR Am J Roentgenol 190: W28-W34
19. Narita M, Hatano E, Arizono S et al (2009) Expression of OATP1B3 determines uptake of Gd-EOB-DTPA in hepatocellular carcinoma. J Gastroenterol 44:793-798