Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio are prolonged in patients with moderate and severe obstructive sleep apnea

PACE - Pacing and Clinical Electrophysiology

Volumn 35, Issue 8, 2012, Pages 966-972

  Kilicaslan, Fethi ^a   Tokatli, Alptug ^a   Ozdag, Fatih ^a   Uzun, Mehmet ^a   Uz, Omer ^a   Isilak, Zafer ^a   Yiginer, Omer ^a   Yalcin, Murat ^a   Guney, Mehmet Senol ^a   Cebeci, Bekir Sitki ^a  

^a GATA HAYDARPASA TRAINING HOSPITAL   (Turkey)

Author keywords

obstructive sleep apnea; Tp e interval; Tp e QT ratio; Tp e QTc ratio

Indexed keywords

ADULT; APNEA HYPOPNEA INDEX; ARTICLE; CALCULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ELECTROCARDIOGRAM; HEART REPOLARIZATION; HUMAN; POLYSOMNOGRAPHY; QT INTERVAL; SLEEP APNEA SYNDROME; T WAVE;

ADULT; ARRHYTHMIAS, CARDIAC; ELECTROCARDIOGRAPHY; FEMALE; HEART VENTRICLES; HUMANS; MALE; MIDDLE AGED; POLYSOMNOGRAPHY; SEVERITY OF ILLNESS INDEX; SLEEP APNEA, OBSTRUCTIVE;

EID: 84864707038     PISSN: 01478389     EISSN: 15408159     Source Type: Journal    
DOI: 10.1111/j.1540-8159.2012.03439.x     Document Type: Article

References (26)

1. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S,. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993; 328: 1230-1235.
2. Kushida CA, Littner MR, Morgenthaler T, Alessi CA, Bailey D, Coleman J Jr, Friedman L, et al,. Practice parameters for the indications for polysomnography and related procedures: An update for 2005. Sleep 2005; 4: 499-521.
3. McNicholas WT, Bonsigore MR,; Management Committee of EU COST ACTION B26. Sleep apnoea as an independent risk factor for cardiovascular disease: Current evidence, basic mechanisms and research priorities. Eur Respir J 2007; 1: 156-178.
4. Gami AS, Howard DE, Olson EJ, Somers VK,. Day-night pattern of sudden death in obstructive sleep apnea. N Engl J Med 2005; 352: 1206-1214.
5. Trinder J, Kleiman J, Carrington M, Smith S, Breen S, Tan N, Kim Y,. Autonomic activity during human sleep as a function of time and sleep stage. J Sleep Res 2001; 10: 253-264.
6. Kors JA, Ritsema van Eck HJ, van Herpen G,. The meaning of the Tp-Te interval and its diagnostic value. J Electrocardiol 2008; 41: 575-580.
7. Gupta P, Patel C, Patel H, Narayanaswamy S, Malhotra B, Green JT, Yan GX,. T(p-e)/QT ratio as an index of arrhythmogenesis. J Electrocardiol 2008; 41: 567-574.
8. Topilski I, Rogowski O, Rosso R, Justo D, Copperman Y, Glikson M, Belhassen B, et al,. The morphology of the QT interval predicts torsade de pointes during acquired bradyarrhythmias. J Am Coll Cardiol 2007; 49: 320-328.
9. Shimizu M, Ino H, Okeie K, Yamaguchi M, Nagata M, Hayashi K, Itoh H, et al,. T-peak to T-end interval may be a better predictor of high-risk patients with hypertrophic cardiomyopathy associated with a cardiac troponin I mutation than QT dispersion. Clin Cardiol 2002; 25: 335-339.
10. Haarmark C, Hansen PR, Vedel-Larsen E, Pedersen SH, Graff C, Andersen MP, Toft E, et al,. The prognostic value of the Tpeak-Tend interval in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. J Electrocardiol 2009; 42: 555-560.
11. Sicouri S, Antzelevitch C,. A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle. The M cell. Circ Res 1991; 68: 1729-1741.
12. Yan GX, Antzelevitch C,. Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome. Circulation 1998; 98: 1928-1936.
13. Panikkath R, Reinier K, Uy-Evanado A, Teodorescu C, Hattenhauer J, Mariani R, Gunson K, et al,. Prolonged Tpeak-to-tend interval on the resting ECG is associated with increased risk of sudden cardiac death. Circ Arrhythm Electrophysiol 2011; 4: 441-447.
14. Guilleminault C, Connolly SJ, Winkle RA,. Cardiac arrhythmia and conduction disturbances during sleep in 400 patients with sleep apnea syndrome. Am J Cardiol 1983; 52: 490-494.
15. Tilkian AG, Guilleminault C, Schroeder JS, Lehrman KL, Simmons FB, Dement WC,. Sleep-induced apnea syndrome. Prevalence of cardiac arrhythmias and their reversal after tracheostomy. Am J Med 1977; 63: 348-358.
16. Hoffstein V, Mateika S,. Cardiac arrhythmias, snoring, and sleep apnea. Chest 1994; 106: 466-471.
17. Mehra R, Benjamin EJ, Shahar E, Gottlieb DJ, Nawabit R, Kirchner HL, Sahadevan J, et al., Sleep Heart Health Study. Association of nocturnal arrhythmias with sleep-disordered breathing: The Sleep Heart Health Study. Am J Respir Crit Care Med 2006; 173: 910-916.
18. Grimm W, Becker HF,. Obesity, sleep apnea syndrome, and arrhythmogenic risk. Herz 2006; 31: 213-218.
19. Watanabe N, Kobayashi Y, Tanno K, Miyoshi F, Asano T, Kawamura M, Mikami Y, et al,. Transmural dispersion of repolarization and ventricular tachyarrhythmias. J Electrocardiol 2004; 37: 191-200.
20. Carlson JT, Hedner J, Elam M, Ejnell H, Sellgren J, Wallin BG,. Augmented resting sympathetic activity in awake patients with obstructive sleep apnea. Chest 1993; 103: 1763-1768.
21. Somers VK, Dyken ME, Clary MP, Abboud FM,. Sympathetic neural mechanism in obstructive sleep apnea. J Clin Invest 1995; 96: 1897-1904.
22. Dursunoglu D, Dursunoglu N, Evrengül H, Ozkurt S, Kiliç M, Fisekci F, Kuru O, et al,. QT interval dispersion in obstructive sleep apnoea syndrome patients without hypertension. Eur Respir J 2005; 25: 677-681.
23. Nakamura T, Chin K, Hosokawa R, Takahashi K, Sumi K, Ohi M, Mishima M,. Corrected QT dispersion and cardiac sympathetic function in patients with obstructive sleep apnea-hypopnea syndrome. Chest 2004; 125: 2107-2114.
24. Barta K, Szabõ Z, Kun C, Munkácsy C, Bene O, Magyar MT, Csiba L, et al,. The effect of sleep apnea on QT interval, QT dispersion, and arrhythmias. Clin Cardiol 2010; 33: 35-39.
25. Baumert M, Smith J, Catcheside P, McEvoy RD, Abbott D, Sanders P, Nalivaiko E,. Variability of QT interval duration in obstructive sleep apnea: An indicator of disease severity. Sleep 2008; 31: 959-966.
26. Namtvedt SK, Randby A, Einvik G, Hrubos-Strom H, Somers VK, Rosjo H, Omland T,. Cardiac arrhythmias in obstructive sleep apnea (from the Akershus Sleep Apnea Project). Am J Cardiol 2011; 108: 1141-1146.