Corylucinine, a new alkaloid from Corydalis cava (fumariaceae), and its cholinesterase activity

Natural Product Communications

Volumn 7, Issue 7, 2012, Pages 859-860

  Novák, Zdenèk ^a   Chlebek, Jakub ^b   Opletal, Lubomír ^b   Jiroš, Pavel ^c   Macáková, Kateřina ^b   Kuneš, Jiří ^a   Cahlíková, Lucie ^b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^c INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

8 Trichloromethyl 7,8 dihydropalmatine; Acetylcholinesterase; Alzheimer's disease; Butyrylcholinesterase; Corydalis cava; Corylucinine

Indexed keywords

8 TRICHLOROMETHYL 7,8 DIHYDROPALMATINE; ACETYLCHOLINESTERASE; ALKALOID; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; CORYLUCININE; GALANTAMINE; HUPERZINE A; PALMATINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CORYDALIS; CORYDALIS CAVA; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ENZYME INHIBITION; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OPTICAL ROTATION; PAPAVERACEAE; PLANT TUBER;

CORYDALIS CAVA; FUMARIACEAE;

EID: 84864704369     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x1200700712     Document Type: Article

References (10)

1. (a) Park SY. (2010) Potential therapeutic agents against Alzheimer's disease from natural sources. Archives of Pharmacal Research, 33, 1589-1609;
2. (b) Lahiri DK, Farlow MR, Greig NH, Sambamurti K. (2002) Current drug targets for Alzheimer's disease treatment. Drug Development Research, 56, 267-281.
3. (a) Orhan I, Sener B, Choudhary MI, Khalid A. (2004) Acetylcholinesterase and butyrylcholinesterase inhibitory activity of some Turkish medicinal plants. Journal of Ethnopharmacology, 91, 57-60;
4. (b) Houghton PJ, Ren Y, Howes MJ. (2006) Acetylcholinesterase inhibitors from plants and fungi. Natural Products Reports, 23, 181-199;
5. (c) Slavík J, Slavíková L. (1979) Alkaloids from Corydalis cava (L.) SCHW. et KOERTE. Collection of Czechoslovak Chemical Communications, 44, 2261-2274;
6. (d) Preininger V, Thakur RS, Šantavý F. (1976) Isolation and chemistry of alkaloids from plants of the family Papaveraceae LXVII: Corydalis cava (L.) Sch. et K. (C. tuberosa DC). Journal of Pharmaceutical Sciences, 65, 294-296;
7. (e) Adsersen A, Kjølbye A, Dall O, Jäger AK. (2007) Acetylcholinesterase and butyrylcholinesterase inhibitory compounds from Corydalis cava Schweigg. & Kort. Journal of Ethnopharmacology, 113, 179-182;
8. (f) Chlebek J, Macáková K, Cahlíková L, Kurfürst M, Kuneš J, Opletal L. (2011) Acetylcholinesterase and butyrylcholinesterase inhibitory compounds from Corydalis cava (Fumariaceae). Natural Product Communications, 6, 607-610.
9. Marek R, Seèkáøová P, Hulová D, Marek J, Dostál J, Sklenáø V. (2003) Palmatine and berberine isolation artifacts. Journal of Natural Products, 66, 481-486.
10. Ellman GL, Courtney KD, Andres V, Featherstone RM. (1961) A new rapid colorimetric determination of acetylcholinesterase activity. Biochemical Pharmacology, 7, 88-95.