Tuning the voltage-sensor motion with a single residue

Biophysical Journal

Volumn 103, Issue 3, 2012, Pages

  Lacroix, Jérôme J ^a   Bezanilla, Francisco ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOLEUCINE; PHOSPHATASE; VOLTAGE SENSOR CONTAINING PHOSPHATASE, CIONA INTESTINALIS; VOLTAGE-SENSOR-CONTAINING PHOSPHATASE, CIONA INTESTINALIS;

AMINO ACID SEQUENCE; ARTICLE; CELL MEMBRANE; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; ELECTRIC CONDUCTIVITY; KINETICS; METABOLISM; MOLECULAR GENETICS; MOVEMENT (PHYSIOLOGY); NUCLEOTIDE SEQUENCE; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; CELL MEMBRANE; CONSERVED SEQUENCE; ELECTRIC CONDUCTIVITY; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; ISOLEUCINE; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOVEMENT; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN STRUCTURE, SECONDARY;

CIONA INTESTINALIS;

EID: 84864704030     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2012.06.030     Document Type: Article

References (10)

1. Y. Murata, and H. Iwasaki Y. Okamura Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor Nature 435 2005 1239 1243 (Pubitemid 40943089)
2. Y. Murata, and Y. Okamura Depolarization activates the phosphoinositide phosphatase Ci-VSP, as detected in Xenopus oocytes coexpressing sensors of PIP2 J. Physiol. 583 2007 875 889 (Pubitemid 47423706)
3. C.A. Villalba-Galea, and W. Sandtner F. Bezanilla S4-based voltage sensors have three major conformations Proc. Natl. Acad. Sci. USA 105 2008 17600 17607
4. X. Chen, and Q. Wang J. Ma Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based x-ray crystallographic refinement Proc. Natl. Acad. Sci. USA 107 2010 11352 11357
5. C.A. Ahern, and R. Horn Focused electric field across the voltage sensor of potassium channels Neuron 48 2005 25 29 (Pubitemid 41384163)
6. D.M. Starace, and F. Bezanilla A proton pore in a potassium channel voltage sensor reveals a focused electric field Nature 427 2004 548 553 (Pubitemid 38209113)
7. O.K. Asamoah, and J.P. Wuskell F. Bezanilla A fluorometric approach to local electric field measurements in a voltage-gated ion channel Neuron 37 2003 85 97 (Pubitemid 36106436)
8. E. Stefani, and F. Bezanilla Cut-open oocyte voltage-clamp technique Methods Enzymol. 293 1998 300 318 (Pubitemid 29342494)
9. + channel voltage sensor Proc. Natl. Acad. Sci. USA 108 2011 6444 6449
10. X. Tao, and A. Lee R. MacKinnon A gating charge transfer center in voltage sensors Science 328 2010 67 73