Effects of block copolymer properties on nanocarrier protection from in vivo clearance

Journal of Controlled Release

Volumn 162, Issue 1, 2012, Pages 208-217

  D'Addio, Suzanne M ^a   Saad, Walid ^a   Ansell, Steven M ^b   Squiers, John J ^a   Adamson, Douglas H ^a   Herrera Alonso, Margarita ^a   Wohl, Adam R ^c   Hoye, Thomas R ^c   MacOsko, Christopher W ^d   Mayer, Lawrence D ^b   Vauthier, Christine ^e,f   Prud'homme, Robert K ^a  

^a Princeton University   (United States)

^b Celator Pharmaceuticals Corp   (Canada)

^c University of Minnesota   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

^e UNIVERSITÉ PARIS SACLAY   (France)

^f UNIV PARIS SUD   (France)

Author keywords

Circulation; Complement activation; Nanoparticle; Polycaprolactone; Polyethylene glycol; Polylactic acid

Indexed keywords

BLOB SIZE; CAPROLACTONE; CIRCULATION TIME; COPOLYMER STRUCTURE; DIRECTED ASSEMBLY; GLYCOLIDE; HYDROPHILIC AND HYDROPHOBIC; HYDROPHILIC BLOCKS; HYDROPHOBIC BLOCKS; IMMUNE SYSTEMS; IN-VITRO; IN-VITRO TESTS; IN-VIVO; L-LACTIDE; LATEX SPHERES; MONODISPERSE; NANOCARRIERS; PACLITAXEL; PATHOLOGICAL TISSUE; POLY LACTIC ACID; POLYMER CRYSTALLINITY; PRODRUGS; RELATIVE RATES; RELATIVE SIZES; TARGETED DELIVERY;

BLOCK COPOLYMERS; BOILER CIRCULATION; HYDROPHILICITY; HYDROPHOBICITY; NANOPARTICLES; POLYCAPROLACTONE; POLYETHYLENE OXIDES; POLYSTYRENES; TISSUE;

POLYETHYLENE GLYCOLS;

COPOLYMER; MACROGOL; NANOCARRIER; PACLITAXEL; POLYCAPROLACTONE; POLYGLACTIN; POLYLACTIDE; POLYSTYRENE;

ANIMAL EXPERIMENT; ARTICLE; DRUG CLEARANCE; HYDROPHOBICITY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DRUG CARRIERS; LACTIC ACID; MICE; MICE, NUDE; NANOSTRUCTURES; PACLITAXEL; POLYESTERS; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; POLYMERS;

EID: 84864700250     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.06.020     Document Type: Article

References (51)

1. F. Alexis, E. Pridgen, L.K. Molnar, and O.C. Farokhzad Factors affecting the clearance and biodistribution of polymeric nanoparticles Mol. Pharm. 5 4 2008 505 515
2. S.M. Ansell, S.A. Johnstone, P.G. Tardi, L. Lo, S.W. Xie, Y. Shu, T.O. Harasym, N.L. Harasym, L. Williams, D. Bermudes, B.D. Liboiron, W. Saad, R.K. Prud'homme, and L.D. Mayer Modulating the therapeutic activity of nanoparticle delivered paclitaxel by manipulating the hydrophobicity of prodrug conjugates J. Med. Chem. 51 11 2008 3288 3296
3. S. Acharya, and S.K. Sahoo PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect Adv. Drug Deliv. Rev. 63 3 2011 170 183
4. Y. Matsumura, and H. Maeda A new concept for macromolecular therapeutics in cancer-chemotherapy - mechanism of tumoritropic accumulation of proteins and the antitumor agent Smancs Cancer Res. 46 12 1986 6387 6392
5. S. Stolnik, S.E. Dunn, M.C. Garnett, M.C. Davies, A.G.A. Coombes, D.C. Taylor, M.P. Irving, S.C. Purkiss, T.F. Tadros, S.S. Davis, and L. Illum Surface modification of poly(lactide-co-glycolide) nanospheres by biodegradable poly(lactide)-poly(ethylene glycol) copolymers Pharm. Res. 11 12 1994 1800 1808
6. J.V. Jokerst, T. Lobovkina, R.N. Zare, and S.S. Gambhir Nanoparticle PEGylation for imaging and therapy Nanomedicine-UK 6 4 2011 715 728
7. D.E. Owens, and N.A. Peppas Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles Int. J. Pharm. 307 1 2006 93 102
8. A.K. Kenworthy, S.A. Simon, and T.J. Mcintosh Structure and phase-behavior of lipid suspensions containing phospholipids with covalently attached poly(ethylene glycol) Biophys. J. 68 5 1995 1903 1920
9. H.S. Ashbaugh, K. Boon, and R.K. Prud'homme Gelation of catanionic vesicles by hydrophobically modified polyelectrolytes Colloid Polym. Sci. 280 9 2002 783 788
10. D.T. Auguste, R.K. Prud'homme, P.L. Ahl, P. Meers, and J. Kohn Association of hydrophobically-modified poly(ethylene glycol) with fusogenic liposomes BBA-Biomembranes 1616 2 2003 184 195
11. C. Ligoure, and L. Leibler Thermodynamics and kinetics of grafting end-functionalized polymers to an interface J Phys.-Paris 51 12 1990 1313 1328
12. P.G. Degennes Conformations of polymers attached to an interface Macromolecules 13 5 1980 1069 1075
13. W. Feng, J.L. Brash, and S.P. Zhu Non-biofouling materials prepared by atom transfer radical polymerization grafting of 2-methacryloloxyethyl phosphorylcholine: separate effects of graft density and chain length on protein repulsion Biomaterials 27 6 2006 847 855
14. M. Himmelhaus, T. Bastuck, S. Tokumitsu, M. Grunze, L. Livadaru, and H.J. Kreuzer Growth of a dense polymer brush layer from solution Europhys. Lett. 64 3 2003 378 384
15. I. Bertholon, C. Vauthier, and D. Labarre Complement activation by core-shell poly(isobutylcyanoacrylate)-polysaccharide nanoparticles: influences of surface morphology, length, and type of polysaccharide Pharm. Res. 23 6 2006 1313 1323
16. R.J. Boackle, G.B. Caughman, J. Vesely, G. Medgyesi, and H.H. Fudenberg Potentiation of factor-H by heparin - a rate-limiting mechanism for inhibition of the alternative complement pathway Mol. Immunol. 20 11 1983 1157 1164
17. N.R. Cooper, G.R. Nemerow, and J.T. Mayes Methods to detect and quantitate complement activation Springer Semin. Immun. 6 2-3 1983 195 212
18. S.P. Henry, P.C. Giclas, J. Leeds, M. Pangburn, C. Auletta, A.A. Levin, and D.J. Kornbrust Activation of the alternative pathway of complement by a phosphorothioate oligonucleotide: potential mechanism of action J. Pharmacol. Exp. Ther. 281 2 1997 810 816
19. V.C.F. Mosqueira, P. Legrand, A. Gulik, O. Bourdon, R. Gref, D. Labarre, and G. Barratt Relationship between complement activation, cellular uptake and surface physicochemical aspects of novel PEG-modified nanocapsules Biomaterials 22 22 2001 2967 2979
20. C. Passirani, G. Barratt, J.P. Devissaguet, and D. Labarre Interactions of nanoparticles bearing heparin or dextran covalently bound to poly(methyl methacrylate) with the complement system Life Sci. 62 8 1998 775 785
21. B.K. Johnson, and R.K. Prud'homme Chemical processing and micromixing in confined impinging jets AICHE J. 49 9 2003 2264 2282
22. Y. Liu, C.Y. Cheng, Y. Liu, R.K. Prud'homme, and R.O. Fox Mixing in a multi-inlet vortex mixer (MIVM) for flash nano-precipitation Chem. Eng. Sci. 63 11 2008 2829 2842
23. T. Chen, S.M. D'Addio, M.T. Kennedy, A. Swietlow, I.G. Kevrekidis, A.Z. Panagiotopoulos, and R.K. Prud'homme Protected peptide nanoparticles: experiments and Brownian dynamics simulations of the energetics of assembly Nano Lett. 9 6 2009 2218 2222
24. H. Chiou, H.K. Chan, D. Heng, R.K. Prud'homme, and J.A. Raper A novel production method for inhalable cyclosporine A powders by confined liquid impinging jet precipitation J. Aerosol Sci. 39 6 2008 500 509
25. V. Kumar, S.Y. Hong, A.E. Maciag, J.E. Saavedra, D.H. Adamson, R.K. Prud'homme, L.K. Keefer, and H. Chakrapani Stabilization of the nitric oxide (NO) prodrugs and anticancer leads, PABA/NO and double JS-K, through incorporation into PEG-protected nanoparticles Mol. Pharm. 7 1 2010 291 298
26. V. Kumar, L. Wang, M. Riebe, H.H. Tung, and R.K. Prud'homme Formulation and stability of ltraconazole and odanacatib nanoparticles: governing physical parameters Mol. Pharm. 6 4 2009 1118 1124
27. S.J. Budijono, B. Russ, W. Saad, D.H. Adamson, and R.K. Prud'homme Block copolymer surface coverage on nanoparticles Colloid Surf. A 360 1-3 2010 105 110
28. S.Y. Zhang, D.H. Adamson, R.K. Prud'homme, and A.J. Link Photocrosslinking the polystyrene core of block-copolymer nanoparticles Polym. Chem. 2 3 2011 665 671
29. B.G.G. Lohmeijer, R.C. Pratt, F. Leibfarth, J.W. Logan, D.A. Long, A.P. Dove, F. Nederberg, J. Choi, C. Wade, R.M. Waymouth, and J.L. Hedrick Guanidine and amidine organocatalysts for ring-opening polymerization of cyclic esters Macromolecules 39 25 2006 8574 8583
30. H.T. Qian, A.R. Wohl, J.T. Crow, C.W. Macosko, and T.R. Hoye A strategy for control of random copolymerization of lactide and glycolide: application to synthesis of PEG-b-PLGA block polymers having narrow dispersity Macromolecules 44 18 2011 7132 7140
31. S.J. Budijono, J.N. Shan, N. Yao, Y. Miura, T. Hoye, R.H. Austin, Y.G. Ju, and R.K. Prud'homme Synthesis of stable block-copolymer-protected NaYF(4):Yb(3+), Er(3+) up-converting phosphor nanoparticles Chem. Mater. 22 2 2010 311 318
32. X.T. Shuai, T. Merdan, F. Unger, M. Wittmar, and T. Kissel Novel biodegradable ternary copolymers hy-PEI-g-PCL-b-PEG: synthesis, characterization, and potential as efficient nonviral gene delivery vectors Macromolecules 36 15 2003 5751 5759
33. W.S. Rasband ImageJ 1997-2011 U. S. National Institutes of Health Bethesda, Maryland, USA http://imagej.nih.gov/ij/
34. Molinspiration Cheminformatics, Nova ulica, SK-900 26 Slovensky Grob, Slovak Republic, www. Molinspiration.com.
35. B. Baleux, and J. Shampetier Colorimetric determination of silver of nonionic polyoxyethylene surface using iodo-iodated solution C. R. Acad. Sci. C Chim. 274 19 1972 1617 1620
36. G.L. Pool, M.E. French, R.A. Edwards, L. Huang, and R.H. Lumb Use of radiolabeled hexadecyl cholesteryl ether as a liposome marker Lipids 17 6 1982 448 452
37. V. Kumar, D.H. Adamson, and R.K. Prud'homme Fluorescent polymeric nanoparticles: aggregation and phase behavior of pyrene and amphotericin B molecules in nanoparticle cores Small 6 24 2011 2907 2914
38. C. Vauthier, B. Persson, P. Lindner, and B. Cabane Protein adsorption and complement activation for di-block copolymer nanoparticles Biomaterials 32 6 2011 1646 1656
39. A.M. Reed, and D.K. Gilding Biodegradable polymers for use in surgery - poly(glycolic)-poly(lactic acid) homo and co-polymers.2. In vitro degradation Polymer 22 4 1981 494 498
40. M.Y. Kozlov, N.S. Melik-Nubarov, E.V. Batrakova, and A.V. Kabanov Relationship between pluronic block copolymer structure, critical micellization concentration and partitioning coefficients of low molecular mass solutes Macromolecules 33 9 2000 3305 3313
41. R. Gref, M. Luck, P. Quellec, M. Marchand, E. Dellacherie, S. Harnisch, T. Blunk, and R.H. Muller 'Stealth' corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption Colloid Surf. B 18 3-4 2000 301 313
42. P. Harder, M. Grunze, R. Dahint, G.M. Whitesides, and P.E. Laibinis Molecular conformation in oligo(ethylene glycol)-terminated self-assembled monolayers on gold and silver surfaces determines their ability to resist protein adsorption J. Phys. Chem. B 102 2 1998 426 436
43. C.L. He, J. Sun, C. Deng, T. Zhao, M.X. Deng, X.S. Chen, and X.B. Jing Study of the synthesis, crystallization, and morphology of poly(ethylene glycol)-poly(epsilon-caprolactone) diblock copolymers Biomacromolecules 5 5 2004 2042 2047
44. G. Biresaw, and C.J. Carriere Correlation between mechanical adhesion and interfacial properties of starch/biodegradable polyester blends J. Polym. Sci. Pol. Phys. 39 9 2001 920 930
45. F. Normand, A. Granier, P. Leprince, J. Marec, M.K. Shi, and F. Clouet Polymer treatment in the flowing afterglow of an oxygen microwave-discharge - active species profile concentrations and kinetics of the functionalization Plasma Chem. Plasma Process. 15 2 1995 173 198
46. H.Y. Erbil, B. Yasar, S. Suzer, and B.M. Baysal Surface characterization of the hydroxy-terminated poly(epsilon-caprolactone)/poly(dimethylsiloxane) triblock copolymers by electron spectroscopy for chemical analysis and contact angle measurements Langmuir 13 20 1997 5484 5493
47. M. Yasin, and B.J. Tighe Polymers for biodegradable medical devices.8. Hydroxybutyrate hydroxyvalerate copolymers - physical and degradative properties of blends with polycaprolactone Biomaterials 13 1 1992 9 16
48. S. Wu Surface and interfacial tensions of polymer melts.2. Poly(methyl methacrylate), poly(normal-butyl methacrylate), and polystyrene J. Phys. Chem. 74 3 1970 632
49. S. Wu Surface and interfacial tensions of polymer melts.I. Polyethylene, polyisobutylene, and polyvinyl acetate J. Colloid Interf. Sci. 31 2 1969 153
50. G. Biresaw, and C.J. Carriere Interfacial tension of poly(lactic acid)/polystyrene blends J. Polym. Sci. Pol. Phys. 40 19 2002 2248 2258
51. M.A. Dobrovolskaia, P. Aggarwal, J.B. Hall, and S.E. McNeil Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution Mol. Pharm. 5 4 2008 487 495