Perfusion MRI for the prediction of treatment response after preoperative chemoradiotherapy in locally advanced rectal cancer

European Radiology

Volumn 22, Issue 8, 2012, Pages 1693-1700

  Lim, Joon Seok ^a   Kim, Daehong ^b   Baek, Song Ee ^a   Myoung, Sungmin ^c   Choi, Junjeong ^a   Shin, Sang Joon ^a   Kim, Myeong Jin ^a   Kim, Nam Kyu ^a   Suh, Jinsuk ^a   Kim, Ki Whang ^a   Keum, Ki Chang ^a  

^a Yonsei University College of Medicine   (South Korea)

^b National Cancer Center   (South Korea)

^c Jungwon University   (South Korea)

Author keywords

Chemoradiotherapy (CRT); Dynamic contrast enhanced MRI; Magnetic resonance imaging (MRI); Perfusion imaging; Rectal cancer

Indexed keywords

FLUOROURACIL; FOLINIC ACID; GADOLINIUM PENTETATE;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER STAGING; CHEMORADIOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTRAST ENHANCEMENT; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; MALE; MULTIPLE CYCLE TREATMENT; NUCLEAR MAGNETIC RESONANCE SCANNER; PERFUSION WEIGHTED IMAGING; PREDICTION; PREDICTIVE VALUE; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECTUM CARCINOMA; THREE DIMENSIONAL IMAGING; TREATMENT RESPONSE; TUMOR REGRESSION;

ADULT; AGED; BIOLOGICAL MARKERS; CARCINOMA; CHEMORADIOTHERAPY; COMBINED MODALITY THERAPY; CONTRAST MEDIA; FEMALE; HUMANS; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MIDDLE AGED; PERFUSION; PERMEABILITY; PROSPECTIVE STUDIES; RECTAL NEOPLASMS; TREATMENT OUTCOME;

EID: 84864699017     PISSN: 09387994     EISSN: 14321084     Source Type: Journal    
DOI: 10.1007/s00330-012-2416-3     Document Type: Article

References (23)

1. Padhani AR, Liu G, Koh DM et al (2009) Diffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recommendations. Neoplasia 11:102-125
2. Gray LH, Conger AD, Ebert M, Hornsey S, Scott OC (1953) The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. Br J Radiol 26:638-648
3. Overgaard J, Horsman MR (1996) Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers. Semin Radiat Oncol 6:10-21. doi:10.1053/SRAO0060010
4. Wolmark N, Piedbois P, Rougier P et al (1998) Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. J Clin Oncol 16:301-308
5. Vaupel P, Kallinowski F, Okunieff P (1989) Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res 49:6449-6465
6. Jain RK (2005) Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307:58-62. doi:10.1126/science.1104819
7. Tofts PS, Brix G, Buckley DL et al (1999) Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging 10:223-232
8. Janssen MH, Aerts HJ, Kierkels RG et al (2010) Tumor perfusion increases during hypofractionated short-course radiotherapy in rectal cancer: sequential perfusion-CT findings. Radiother Oncol 94:156-160. doi:10.1016/j.radonc.2009.12. 013
9. Bellomi M, Petralia G, Sonzogni A, Zampino MG, Rocca A (2007) CT perfusion for the monitoring of neoadjuvant chemotherapy and radiation therapy in rectal carcinoma: initial experience. Radiology 244:486-493. doi:10.1148/radiol.2442061189
10. Sahani DV, Kalva SP, Hamberg LM et al (2005) Assessing tumor perfusion and treatment response in rectal cancer with multisection CT: initial observations. Radiology 234:785-792. doi:10.1148/radiol.2343040286
11. Tofts PS (1997) Modeling tracer kinetics in dynamic Gd-DTPA MR imaging. J Magn Reson Imaging 7:91-101
12. George ML, Dzik-Jurasz AS, Padhani AR et al (2001) Noninvasive methods of assessing angiogenesis and their value in predicting response to treatment in colorectal cancer. Br J Surg 88:1628-1636. doi:10.1046/j.0007-1323.2001.01947.x
13. Tofts PS, Kermode AG (1991) Measurement of the blood-brain barrier permeability and leakage space using dynamic MR imaging. 1. Fundamental concepts. Magn Reson Med 17:357-367
14. Weinmann HJ, Laniado M, Mutzel W (1984) Pharmacokinetics of GdDTPA/dimeglumine after intravenous injection into healthy volunteers. Physiol Chem Phys Med NMR 16:167-172
15. Mandard AM, Dalibard F, Mandard JC et al (1994) Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma. Clinicopathologic correlations. Cancer 73:2680-2686
16. Vecchio FM, Valentini V, Minsky BD et al (2005) The relationship of pathologic tumor regression grade (TRG) and outcomes after preoperative therapy in rectal cancer. Int J Radiat Oncol Biol Phys 62:752-760. doi:10.1016/j.ijrobp. 2004.11.017
17. Cooper RA, Carrington BM, Loncaster JA et al (2000) Tumour oxygenation levels correlate with dynamic contrast-enhanced magnetic resonance imaging parameters in carcinoma of the cervix. Radiother Oncol 57:53-59
18. Janjan NA, Crane C, Feig BW et al (2001) Improved overall survival among responders to preoperative chemoradiation for locally advanced rectal cancer. Am J Clin Oncol 24:107-112
19. Sun YS, Zhang XP, Tang L et al (2010) Locally advanced rectal carcinoma treated with preoperative chemotherapy and radiation therapy: preliminary analysis of diffusion-weighted MR imaging for early detection of tumor histopathologic downstaging. Radiology 254:170-178. doi:10.1148/radiol. 2541082230
20. Mayr NA, Yuh WT, Magnotta VA et al (1996) Tumor perfusion studies using fast magnetic resonance imaging technique in advanced cervical cancer: a new noninvasive predictive assay. Int J Radiat Oncol Biol Phys 36:623-633
21. Harvey C, Dooher A, Morgan J, Blomley M, Dawson P (1999) Imaging of tumour therapy responses by dynamic CT. Eur J Radiol 30:221-226
22. Wheeler JM, Warren BF, Jones AC, Mortensen NJ (1999) Preoperative radiotherapy for rectal cancer: implications for surgeons, pathologists and radiologists. Br J Surg 86:1108-1120. doi:10.1046/j.1365-2168.1999.01209.x
23. Dworak O, Keilholz L, Hoffmann A (1997) Pathological features of rectal cancer after preoperative radiochemotherapy. Int J Colorectal Dis 12:19-23