메뉴 건너뛰기




Volumn 53, Issue 2, 2012, Pages 50-55

Neisseria meningitidis: Pathogenetic mechanisms to overcome the human immune defences

Author keywords

Immune system; Neisseria meningitidis; Pathogenetic factors; Vaccines; Virulence

Indexed keywords

ADHESIN; BACTERIAL ANTIGEN; FICOLIN; HEPARIN; INTEGRIN; LIPOPOLYSACCHARIDE; MANNAN BINDING LECTIN; NEISSERIAL ADHESIN A; NEISSERIAL HEPARIN BINDING ANTIGEN; PILIN; PORIN A; UNCLASSIFIED DRUG; VITRONECTIN;

EID: 84864687895     PISSN: 11212233     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (15)

References (36)
  • 1
    • 69049111804 scopus 로고    scopus 로고
    • Quest for a broad-range vaccine against Neisseria meningitidis serogroup B: Implications of genetic variations of the surface-exposed proteins
    • De Filippis I. Quest for a broad-range vaccine against Neisseria meningitidis serogroup B: implications of genetic variations of the surface-exposed proteins. J Med Microbiol 2009;58(Pt 9):1127-32.
    • (2009) J Med Microbiol , vol.58 , Issue.PART 9 , pp. 1127-1132
    • De Filippis, I.1
  • 2
    • 67349229381 scopus 로고    scopus 로고
    • Editorial: An update on bacterial stress response
    • Ron EZ. Editorial: An update on bacterial stress response. Res Microbiol 2009;160:243-4.
    • (2009) Res Microbiol , vol.160 , pp. 243-244
    • Ron, E.Z.1
  • 3
    • 67449095212 scopus 로고    scopus 로고
    • Mechanisms of avoidance of host immunity by Neisseria meningitidis and its effect on vaccine development
    • Lo H, Tang CM, Exley RM. Mechanisms of avoidance of host immunity by Neisseria meningitidis and its effect on vaccine development. Lancet Infect Dis 2009;9:418-27.
    • (2009) Lancet Infect Dis , vol.9 , pp. 418-427
    • Lo, H.1    Tang, C.M.2    Exley, R.M.3
  • 4
    • 67349278813 scopus 로고    scopus 로고
    • On the relationship between meningococcal transmission dynamics and disease: Remarks on humoral immunity
    • Guzzetta G, Manfredi P, Gasparini R, et al. On the relationship between meningococcal transmission dynamics and disease: remarks on humoral immunity. Vaccine 2009;27:3429-34.
    • (2009) Vaccine , vol.27 , pp. 3429-3434
    • Guzzetta, G.1    Manfredi, P.2    Gasparini, R.3
  • 5
    • 67349249790 scopus 로고    scopus 로고
    • Seroprevalence of bactericidal antibody against Neisseria meningitidis serogroup C in pre-vaccinal era: The Italian epidemiological scenario
    • 27
    • Gasparini R, Rizzetto R, Sasso T, et al. Seroprevalence of bactericidal antibody against Neisseria meningitidis serogroup C in pre-vaccinal era: the Italian epidemiological scenario. Vaccine. 2009;26:27:3435-8.
    • (2009) Vaccine , vol.26 , pp. 3435-3438
    • Gasparini, R.1    Rizzetto, R.2    Sasso, T.3
  • 6
    • 80052725374 scopus 로고    scopus 로고
    • Carriage of Neisseria meningitidis in Europe: A review of studies undertaken in the region
    • Soriano-Gabarrò M, Wolter J, Hogea C, et al. Carriage of Neisseria meningitidis in Europe: a review of studies undertaken in the region. Expert Rev Anti Infect Ther 2011;9:761-74.
    • (2011) Expert Rev Anti Infect Ther , vol.9 , pp. 761-774
    • Soriano-Gabarrò Wolter M, J.1    Hogea, C.2
  • 7
    • 0034629478 scopus 로고    scopus 로고
    • Complete genome sequence of Neisseria meningitidis serogroup B strain MC58
    • DOI 10.1126/science.287.5459.1809
    • Tettelin H, Saunders NJ, Heidelberg J, et al. Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. Science 2000;287:1809-15. (Pubitemid 30143964)
    • (2000) Science , vol.287 , Issue.5459 , pp. 1809-1815
    • Tettelin, H.1
  • 8
    • 76849105930 scopus 로고    scopus 로고
    • Cellular and molecular biology of Neisseria meningitidis colonization and invasive disease
    • Hill DJ, Griffiths NJ, Borodina E, et al. Cellular and molecular biology of Neisseria meningitidis colonization and invasive disease. Clin Sci (Lond) 2010;118:547-64.
    • (2010) Clin Sci (Lond) , vol.118 , pp. 547-564
    • Hill, D.J.1    Griffiths, N.J.2    Borodina, E.3
  • 9
    • 33747872707 scopus 로고    scopus 로고
    • Type IV pilus structure by cryo-electron microscopy and crystallography: Implications for pilus assembly and functions
    • DOI 10.1016/j.molcel.2006.07.004, PII S1097276506004813
    • Craig L, Volkmann N, Arvai AS, et al. Type IV pilus structure by cryo-electron microscopy and crystallography: implications for pilus assembly and functions. Mol Cell 2006;23:651-62. (Pubitemid 44292553)
    • (2006) Molecular Cell , vol.23 , Issue.5 , pp. 651-662
    • Craig, L.1    Volkmann, N.2    Arvai, A.S.3    Pique, M.E.4    Yeager, M.5    Egelman, EdwardH.6    Tainer, J.A.7
  • 10
    • 18444380597 scopus 로고    scopus 로고
    • The PilC adhesin of the Neisseria type IV pilus - binding specificities and new insights into the nature of the host cell receptor
    • DOI 10.1111/j.1365-2958.2005.04600.x
    • Kirchner M, Meyer TF. The PilC adhesin of the Neisseria type IV pilus-binding specificities and new insights into the nature of the host cell receptor. Mol Microbiol 2005;56:945-57. (Pubitemid 40646767)
    • (2005) Molecular Microbiology , vol.56 , Issue.4 , pp. 945-957
    • Kirchner, M.1    Meyer, T.F.2
  • 11
    • 67651007158 scopus 로고    scopus 로고
    • Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models
    • Orihuela CJ, Mahdavi J, Thornton J, et al. Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models. J Clin Invest 2009;119:1638-46.
    • (2009) J Clin Invest , vol.119 , pp. 1638-1646
    • Orihuela, C.J.1    Mahdavi, J.2    Thornton, J.3
  • 12
    • 0029848536 scopus 로고    scopus 로고
    • Carcinoembryonic antigens (CD66) on epithelial cells and neutrophils are receptors for Opa proteins of pathogenic neisseriae
    • Virji M, Makepeace K, Ferguson DJ, et al. Carcinoembryonic antigens (CD66) on epithelial cells and neutrophils are receptors for Opa proteins of pathogenic neisseriae. Mol Microbiol 1996;22:941-50. (Pubitemid 26411338)
    • (1996) Molecular Microbiology , vol.22 , Issue.5 , pp. 941-950
    • Virji, M.1    Makepeace, K.2    Ferguson, D.J.P.3    Watt, S.M.4
  • 13
    • 0029844602 scopus 로고    scopus 로고
    • The N-domain of the human CD66a adhesion molecule is a target for Opa proteins of Neisseria meningitidis and Neisseria gonorrhoeae
    • Virji M, Watt SM, Barker S, et al. The N-domain of the human CD66a adhesion molecule is a target for Opa proteins of Neisseria meningitidis and Neisseria gonorrhoeae. Mol Microbiol 1996;22:929-39. (Pubitemid 26411337)
    • (1996) Molecular Microbiology , vol.22 , Issue.5 , pp. 929-939
    • Virji, M.1    Watt, S.M.2    Barker, S.3    Makepeace, K.4    Doyonnas, R.5
  • 14
    • 0032752835 scopus 로고    scopus 로고
    • Critical determinants of host receptor targeting by Neisseria meningitidis and Neisseria gonorrhoeae: Identification of Opa adhesiotopes on the N-domain of CD66 molecules
    • DOI 10.1046/j.1365-2958.1999.01620.x
    • Virji M, Evans D, Hadfield A, et al. Critical determinants of host receptor targeting by Neisseria meningitidis and Neisseria gonorrhoeae: identification of Opa adhesiotopes on the Ndomain of CD66 molecules. Mol Microbiol 1999;34:538-51. (Pubitemid 29507314)
    • (1999) Molecular Microbiology , vol.34 , Issue.3 , pp. 538-551
    • Virji, M.1    Evans, D.2    Hadfield, A.3    Grunert, F.4    Telxeira, A.M.5    Watt, S.M.6
  • 15
    • 59849114947 scopus 로고    scopus 로고
    • Neisseria meningitidis Opc invasin binds to the cytoskeletal protein α-actinin
    • Cunha CS, Griffiths NJ, Murillo I, et al. Neisseria meningitidis Opc invasin binds to the cytoskeletal protein α-actinin. Cell Microbiol 2009;11:389-405.
    • (2009) Cell Microbiol , vol.11 , pp. 389-405
    • Cunha, C.S.1    Griffiths, N.J.2    Murillo, I.3
  • 16
    • 38649093998 scopus 로고    scopus 로고
    • 2. Dendritic cells as regulators of immunity and tolerance
    • DOI 10.1016/j.jaci.2007.06.001, PII S0091674907010433
    • Novak N, Bieber T. 2: Dendritic cells as regulators of immunity and tolerance. J Allergy Clin Immunol 2008;121(2 suppl):S370-74. (Pubitemid 351172419)
    • (2008) Journal of Allergy and Clinical Immunology , vol.121 , Issue.2 SUPPL. 2
    • Novak, N.1    Bieber, T.2
  • 18
    • 0036120419 scopus 로고    scopus 로고
    • Lipooligosaccharide and polysaccharide capsule: Virulence factors of Neisseria meningitidis that determine meningococcal interaction with human dendritic cells
    • DOI 10.1128/IAI.70.5.2454-2462.2002
    • Unkmeir A, Kammerer U, Stade A, et al. Lipooligosaccharide and polysaccharide capsule: virulence factors of Neisseria meningitides that determine meningococcal interaction with human dendritic cells. Infect Immun 2002;70:2454-62. (Pubitemid 34408387)
    • (2002) Infection and Immunity , vol.70 , Issue.5 , pp. 2454-2462
    • Unkmeir, A.1    Kammerer, U.2    Stade, A.3    Hubner, C.4    Haller, S.5    Kolb-Maurer, A.6    Frosch, M.7    Dietrich, G.8
  • 19
    • 23844536486 scopus 로고    scopus 로고
    • Carbohydrate composition of meningococcal lipopolysaccharide modulates the interaction of Neisseria meningitidis with human dendritic cells
    • DOI 10.1111/j.1462-5822.2005.00559.x
    • Kurzai O, Schmitt C, Claus H, et al. Carbohydrate composition of meningococcal lipopolysaccharide modulates the interaction of Neisseria meningitidis with human dendritic cells. Cell Microbiol 2005;7:1319-34. (Pubitemid 41179424)
    • (2005) Cellular Microbiology , vol.7 , Issue.9 , pp. 1319-1334
    • Kurzai, O.1    Schmitt, C.2    Claus, H.3    Vogel, U.4    Frosch, M.5    Kolb-Maurer, A.6
  • 20
    • 35948950236 scopus 로고    scopus 로고
    • The differential response of human dendritic cells to live and killed Neisseria meningitidis
    • DOI 10.1111/j.1462-5822.2007.01001.x
    • Jones HE, Uronen-Hansson H, Callard RE, et al. The differential response of human dendritic cells to live and killed Neisseria meningitidis. Cell Microbiol 2007;9:2856-69. (Pubitemid 350066570)
    • (2007) Cellular Microbiology , vol.9 , Issue.12 , pp. 2856-2869
    • Jones, H.E.1    Uronen-Hansson, H.2    Callard, R.E.3    Klein, N.4    Dixon, G.L.J.5
  • 21
    • 34447561633 scopus 로고    scopus 로고
    • Neutrophil granules: A library of innate immunity proteins
    • DOI 10.1016/j.it.2007.06.002, PII S1471490607001561
    • Borregaard N, Sorensen OE, Theilgaard-Monch K. Neutrophil granules: a library of innate immunity proteins. Trends Immunol 2007;28:340-5. (Pubitemid 47077924)
    • (2007) Trends in Immunology , vol.28 , Issue.8 , pp. 340-345
    • Borregaard, N.1    Sorensen, O.E.2    Theilgaard-Monch, K.3
  • 22
    • 57649162572 scopus 로고    scopus 로고
    • Discrimination between host and pathogens by the complement system
    • Pangburn MK, Ferreira V, Cortes C. Discrimination between host and pathogens by the complement system. Vaccine 2008;26S:I15-I21.
    • (2008) Vaccine , vol.26 S
    • Pangburn, M.K.1    Ferreira, V.2    Cortes, C.3
  • 23
    • 47249130305 scopus 로고    scopus 로고
    • Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation
    • Xu W, Berger SP, Trouw LA, et al. Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation. J Immunol 2008;180:7613-21.
    • (2008) J Immunol , vol.180 , pp. 7613-7621
    • Xu, W.1    Berger, S.P.2    Trouw, L.A.3
  • 24
    • 34548321364 scopus 로고    scopus 로고
    • Complement activating soluble pattern recognition molecules with collagen-like regions, mannan-binding lectin, ficolins and associated proteins
    • DOI 10.1016/j.molimm.2007.06.005, PII S0161589007002593, XIth European meeting on Complement in Human Disease
    • Thiel S. Complement activating soluble pattern recognition molecules with collagen-like regions, mannan-binding lectin, ficolins and associated proteins. Mol Immunol 2007;44:3875-88. (Pubitemid 47337117)
    • (2007) Molecular Immunology , vol.44 , Issue.16 , pp. 3875-3888
    • Thiel, S.1
  • 26
    • 34247627993 scopus 로고    scopus 로고
    • Interactions between Neisseria meningitidis and the complement system
    • DOI 10.1016/j.tim.2007.03.005, PII S0966842X07000480
    • Schneider MC, Exely RM, Ram S, et al. Interactions between Neisseria meningitidis and the complement system. Trends Microbiol 2007;15:233-40. (Pubitemid 46671509)
    • (2007) Trends in Microbiology , vol.15 , Issue.5 , pp. 233-240
    • Schneider, M.C.1    Exley, R.M.2    Ram, S.3    Sim, R.B.4    Tang, C.M.5
  • 27
    • 0037352743 scopus 로고    scopus 로고
    • Large-scale analysis of the meningococcus genome by gene distruption: Resistance to complement-mediated lysis
    • DOI 10.1101/gr.664303
    • Geoffroy MC, Floquet S, Metais A, et al. Large-scale analysis of the meningococcus genome by gene disruption: resistance to complement-mediated lysis. Genome Res 2003;13:391-8. (Pubitemid 36395396)
    • (2003) Genome Research , vol.13 , Issue.3 , pp. 391-398
    • Geoffroy, M.-C.1    Floquet, S.2    Metais, A.3    Nassif, X.4    Pelicic, V.5
  • 28
    • 57649220619 scopus 로고    scopus 로고
    • Factor H and Neisserial pathogenesis
    • Welsch JA, Ram S. Factor H and Neisserial pathogenesis. Vaccine 2008;26(Suppl 8):I40-145.
    • (2008) Vaccine , vol.26 , Issue.SUPPL. 8
    • Welsch, J.A.1    Ram, S.2
  • 29
    • 77957652922 scopus 로고    scopus 로고
    • The meningococcal vaccine candidate neisserial surface protein A (NspA) binds to factor H and enhances meningococcal resistance to complement
    • (2010)
    • Lewis LA, Ngampasutadol J, Wallace R, et al. The meningococcal vaccine candidate neisserial surface protein A (NspA) binds to factor H and enhances meningococcal resistance to complement. PLoS Pathog 2010.6(7),e1001027 (2010).
    • (2010) PLoS Pathog , vol.6 , Issue.7
    • Lewis, L.A.1    Ngampasutadol, J.2    Wallace, R.3
  • 30
    • 77649265923 scopus 로고    scopus 로고
    • Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans
    • Serruto D, Spadafina T, Ciucchi L, et al. Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans. Proc Natl Acad Sci USA 2010;107:3770-5.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 3770-3775
    • Serruto, D.1    Spadafina, T.2    Ciucchi, L.3
  • 31
    • 0031918338 scopus 로고    scopus 로고
    • Characterization of the gene cassette required for biosynthesis of the (α1→6)-linked N-acetyl-D-mannosamine-1-phosphate capsule of serogroup A Neisseria meningitidis
    • Swartley JS, Liu LJ, Miller YK, et al. Characterization of the gene cassette required for biosynthesis of the (α1→6)-linked N-acetyl-d-mannosamine-1-phosphate capsule of serogroup A Neisseria meningitidis. J. Bacteriol 1998;180:1533-9. (Pubitemid 28125739)
    • (1998) Journal of Bacteriology , vol.180 , Issue.6 , pp. 1533-1539
    • Swartley, J.S.1    Liu, L.-J.2    Miller, Y.K.3    Martin, L.E.4    Edupuganti, S.5    Stephens, D.S.6
  • 32
    • 34250795027 scopus 로고    scopus 로고
    • Epidemic meningitis, meningococcaemia, and Neisseria meningitidis
    • DOI 10.1016/S0140-6736(07)61016-2, PII S0140673607610162
    • Stephens DS, Greenwood B, Brandtzaeg P. Epidemic meningitis, meningococcaemia, and Neisseria meningitidis. Lancet 2007;369:2196-210. (Pubitemid 46977462)
    • (2007) Lancet , vol.369 , Issue.9580 , pp. 2196-2210
    • Stephens, D.S.1    Greenwood, B.2    Brandtzaeg, P.3
  • 34
    • 67349101201 scopus 로고    scopus 로고
    • Meningococcal interactions with the host
    • Carbonnelle E, Hill DJ, Morand P, et al. Meningococcal interactions with the host. Vaccine 2009;27(Suppl. 2): B78-B89.
    • (2009) Vaccine , vol.27 , Issue.SUPPL. 2
    • Carbonnelle, E.1    Hill, D.J.2    Morand, P.3
  • 35
    • 0029077758 scopus 로고
    • Investigations into the molecular basis of meningococcal toxicity for human endothelial and epithelial cells: The synergistic effect of LPS and pili
    • Dunn KL, Virji M, Moxon ER. Investigations into the molecular basis of meningococcal toxicity for human endothelial and epithelial cells: the synergistic effect of LPS and pili. Microb Pathog 1995;18:81-96.
    • (1995) Microb Pathog , vol.18 , pp. 81-96
    • Dunn, K.L.1    Virji, M.2    Moxon, E.R.3
  • 36
    • 33750469360 scopus 로고    scopus 로고
    • Comparison of the inflammatory responses of human meningeal cells following challenge with Neisseria lactamica and with Neisseria meningitidis
    • DOI 10.1128/IAI.00644-06
    • Fowler MI, Yin KY, Humphries HE, et al. Comparison of the inflammatory responses of human meningeal cells following challenge with Neisseria lactamica and with Neisseria meningitidis. Infect Immun 2006;74:6467-78. (Pubitemid 44657429)
    • (2006) Infection and Immunity , vol.74 , Issue.11 , pp. 6467-6478
    • Fowler, M.I.1    Ho Wang Yin, K.Y.2    Humphries, H.E.3    Heckels, J.E.4    Christodoulides, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.