Pharmacokinetics and bioavailability of cimicifugosides after oral administration of Cimicifuga foetida L. extract to rats

Journal of Ethnopharmacology

Volumn 143, Issue 1, 2012, Pages 249-255

  Gai, Yun Yun ^a,b   Liu, Wan Hui ^b   Sha, Chun Jie ^b   Wang, Ying Lin ^b   Sun, Yan Tong ^a   Li, Xiao Jiao ^a   Paul Fawcett, J ^c   Gu, Jing Kai ^a  

^a JILIN UNIVERSITY   (China)

^b State Key Laboratory of Long acting and Targeting Drug Delivery Technologies   (China)

^c UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Bioavailability; Cimicifugosides; LC MS MS; Pharmacokinetics; Rat plasma

Indexed keywords

23 EPI 26 DEOXYACTEIN; 25 O ACETYLCIMIGENOSIDE; CIMICIFUGA FOETIDA EXTRACT; CIMICIFUGOSIDE H 1; CIMIGENOLXYLOSIDE; HERBACEOUS AGENT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CIMICIFUGA; CIMICIFUGA FOETIDA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG ISOLATION; DRUG STRUCTURE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CIMICIFUGA; LANOSTEROL; LINEAR MODELS; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY;

CIMICIFUGA FOETIDA; RATTUS;

EID: 84864683730     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.06.031     Document Type: Article

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