The in vivo performance of osteochondral allografts in the goat is diminished with extended storage and decreased cartilage cellularity

American Journal of Sports Medicine

Volumn 40, Issue 8, 2012, Pages 1814-1823

  Pallante, Andrea L ^a   Chen, Albert C ^a   Ball, Scott T ^b   Amiel, David ^b   Masuda, Koichi ^b   Sah, Robert L ^b,c   Bugbee, William D ^b,c,d  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d SCRIPPS CLINIC   (United States)

Author keywords

animal models; cartilage repair; chondrocyte viability; fresh stored osteochondral allografts

Indexed keywords

ALLOTRANSPLANTATION; ANIMAL; ANIMAL MODEL; ARTICLE; BONE TRANSPLANTATION; CARTILAGE; CARTILAGE CELL; CELL SURVIVAL; GOAT; LABORATORY DIAGNOSIS; PATHOLOGY; TIME; TRANSPLANTATION;

ANIMALS; BONE TRANSPLANTATION; CARTILAGE; CELL SURVIVAL; CHONDROCYTES; GOATS; MODELS, ANIMAL; SPECIMEN HANDLING; TIME FACTORS; TRANSPLANTATION, HOMOLOGOUS;

EID: 84864650961     PISSN: 03635465     EISSN: 15523365     Source Type: Journal    
DOI: 10.1177/0363546512449321     Document Type: Article

References (44)

1. Guidance for Industry: Screening and Testing of Human Tissue Intended for Transplantation. Rockville, MD: Food and Drug Administration Center for Biologics Evaluation and Research ; 2002
2. Ateshian GA, Lai WM, Zhu WB, Mow VC. An asymptotic solution for the contact of two biphasic cartilage layers. J Biomech. 1994 ; 27: 1347-1360
3. Ball ST, Amiel D, Williams SK, et al. The effects of storage media on fresh human osteochondral allografts. Clin Orthop Relat Res. 2004 ; 418: 246-252
4. Beaver RJ, Mahomed M, Backstein D, Davis A, Zukor DJ, Gross AE. Fresh osteochondral allografts for post-traumatic defects in the knee. J Bone Joint Surg Br. 1992 ; 74: 105-110
5. Bian L, Stoker AM, Marberry KM, Ateshian GA, Cook JL, Hung CT. Effects of dexamethasone on the functional properties of cartilage explants during long-term culture. Am J Sports Med. 2010 ; 38: 78-85
6. Borazjani BH, Chen AC, Bae WC, et al. The effect of impact on chondrocyte viability during the insertion of human osteochondral grafts. J Bone Joint Surg. 2006 ; 88: 1934-1943
7. Bugbee WD. Fresh osteochondral allografts. J Knee Surg. 2002 ; 15: 191-195
8. Chen CT, Burton-Wurster N, Borden C, Hueffer K, Bloom SE, Lust G. Chondrocyte necrosis and apoptosis in impact damaged articular cartilage. J Orthop Res. 2001 ; 19: 703-711
9. Chu CR, Convery FR, Akeson WH, Meyers M, Amiel D. Articular cartilage transplantation: clinical results in the knee. Clin Orthop Relat Res. 1999 ; 360: 159-168
10. Chu CR, Szczodry M, Bruno S. Animal models for cartilage regeneration and repair. Tissue Eng Part B Rev. 2010 ; 16: 105-115
11. Davidson PA, Rivenburgh DW, Dawson PE, Rozin R. Clinical, histologic, and radiographic outcomes of distal femoral resurfacing with hypothermically stored osteoarticular allografts. Am J Sports Med. 2007 ; 35: 1082-1090
12. Emmerson BC, Gortz S, Jamali AA, Chung C, Amiel D, Bugbee WD. Fresh osteochondral allografting in the treatment of osteochondritis dissecans of the femoral condyle. Am J Sports Med. 2007 ; 35: 907-914
13. Fortier LA, Mohammed HO, Lust G, Nixon AJ. Insulin-like growth factor-I enhances cell-based repair of articular cartilage. J Bone Joint Surg Br. 2002 ; 84: 276-288
14. Glantz SA Primer of Biostatistics. 3 rd ed.San Francisco, CA: McGraw-Hill; 1992. San Francisco, CA: McGraw-Hill ; 1992
15. Gulotta LV, Rudzki JR, Kovacevic D, et al. Chondrocyte death and cartilage degradation after autologous osteochondral transplantation surgery in a rabbit model. Am J Sports Med. 2009 ; 37: 1324-1333
16. Jackson DW, Lalor PA, Aberman HM, Simon TM. Spontaneous repair of full-thickness defects of articular cartilage in a goat model: a preliminary study. J Bone Joint Surg Am. 2001 ; 83: 53-64
17. Jadin KD, Wong BL, Bae WC, et al. Depth-varying density and organization of chondrocyte in immature and mature bovine articular cartilage assessed by 3-D imaging and analysis. J Histochem Cytochem. 2005 ; 53: 1109-1119
18. Jamali AA, Emmerson BC, Chung C, Convery FR, Bugbee WD. Fresh osteochondral allografts: results in the patellofemoral joint. Clin Orthop Relat Res. 2005 ; 437: 176-185
19. Kang RW, Friel NA, Williams JM, Cole BJ, Wimmer MA. Effect of impaction sequence on osteochondral graft damage: the role of repeated and varying loads. Am J Sports Med. 2010 ; 38: 105-113
20. LaPrade RF, Botker J, Herzog M, Agel J. Refrigerated osteoarticular allografts to treat articular cartilage defects of the femoral condyles: a prospective outcomes study. J Bone Joint Surg Am. 2009 ; 91: 805-811
21. Malinin T, Temple HT, Buck BE. Transplantation of osteochondral allografts after cold storage. J Bone Joint Surg Am. 2006 ; 88: 762-770
22. McCarty WJ, Pallante AL, Rone RJ, Bugbee WD, Sah RL. The proteoglycan metabolism of articular cartilage in joint-scale culture. Tissue Eng Part A. 2010 ; 16: 1717-1727
23. McCulloch PC, Kang RW, Sobhy MH, Hayden JK, Cole BJ. Prospective evaluation of prolonged fresh osteochondral allograft transplantation of the femoral condyle: minimum 2-year follow-up. Am J Sports Med. 2007 ; 35: 411-420
24. McDermott AG, Langer F, Pritzker KP, Gross AE. Fresh small-fragment osteochondral allografts: long-term follow-up study on first 100 cases. Clin Orthop Relat Res. 1985 ; 197: 96-102
25. Nunamaker DM Textbook of Small Animal Orthopaedics. Newton CD Nunamaker DM, ed. Ithaca, NY: International Veterinary Information ; 1985
26. Oates KM, Chen AC, Young EP, Kwan MK, Amiel D, Convery FR. Effect of tissue culture storage on the in vivo survival of canine osteochondral allografts. J Orthop Res. 1995 ; 13: 562-569
27. Pallante AL, Bae WC, Chen AC, Gortz S, Bugbee WD, Sah RL. Chondrocyte viability is higher after prolonged storage at 37 degrees C than at 4 degrees C for osteochondral grafts. Am J Sports Med. 2009 ; 37: 24S - 32S
28. Pallante AL, Gortz S, Chen AC, et al. Association of osteochondral allograft efficacy with PRG4 secretion in vivo in the goat. Trans Orthop Res Soc. 2011 2099 ; 36
29. Pallante AL, Gortz S, Chen AC, et al. Treatment of articular cartilage defects in the goat with frozen versus fresh osteochondral allografts: effects on cartilage stiffness, zonal composition, and structure at six months. J Bone Joint Surg.
30. Palmer AW, Guldberg RE, Levenston ME. Analysis of cartilage matrix fixed charge density and three-dimensional morphology via contrast-enhanced microcomputed tomography. Proc Natl Acad Sci USA. 2006 ; 103: 19255-19260
31. Patil S, Butcher W, D'Lima DD, Steklov N, Bugbee WD, Hoenecke HR. Effect of osteochondral graft insertion forces on chondrocyte viability. Am J Sports Med. 2008 ; 36: 1726-1732
32. Pearsall AW, Tucker JA, Hester RB, Heitman RJ. Chondrocyte viability in refrigerated osteochondral allografts used for transplantation within the knee. Am J Sports Med. 2004 ; 32: 125-131
33. Pennock AT, Wagner F, Robertson CM, Harwood FL, Bugbee WD, Amiel D. Prolonged storage of osteochondral allografts: does the addition of fetal bovine serum improve chondrocyte viability?. J Knee Surg. 2006 ; 19: 265-272
34. Ranawat AS, Vidal AF, Chen CT, Zelken JA, Turner AS, Williams RJ. Material properties of fresh cold-stored allografts for osteochondral defects at 1 year. Clin Orthop Relat Res. 2008 ; 466: 1826-1836
35. Schmidt TA, Gastelum NS, Nguyen QT, Schumacher BL, Sah RL. Boundary lubrication of articular cartilage: role of synovial fluid constituents. Arthritis Rheum. 2007 ; 56: 882-891
36. Schumacher BL, Hughes CE, Kuettner KE, Caterson B, Aydelotte MB. Immunodetection and partial cDNA sequence of the proteoglycan, superficial zone protein, synthesized by cells lining synovial joints. J Orthop Res. 1999 ; 17: 110-120
37. Shahgaldi BF, Amis AA, Heatley FW, McDowell J, Bentley G. Repair of cartilage lesions using biological implants. J Bone Joint Surg Br. 1991 ; 73: 57-64
38. Shapiro F, Glimcher MJ. Induction of osteoarthrosis in the rabbit knee joint: histologic changes following menisectomy and meniscal lesions. Clin Orthop Relat Res. 1980 ; 147: 287-295
39. Szczodry M, Coyle CH, Kramer SJ, Smolinski P, Chu CR. Progressive chondrocyte death after impact injury indicates a need for chondroprotective therapy. Am J Sports Med. 2009 ; 37: 2318-2322
40. Torga Spak R, Teitge RA. Fresh osteochondral allografts for patellofemoral arthritis: long-term followup. Clin Orthop Relat Res. 2006 ; 444: 193-200
41. Torzilli PA, Grigiene R, Borrelli J, Helfet DL. Effect of impact load on articular cartilage: cell metabolism and viability, and matrix water content. J Biomech Eng. 1999 ; 121: 433-441
42. Williams JM, Virdi AS, Pylawka TK, Edwards RB, Markel MD, Cole BJ. Prolonged-fresh preservation of intact whole canine femoral condyles for the potential use as osteochondral allografts. J Orthop Res. 2005 ; 23: 831-837
43. Williams RJ, Dreese JC, Chen CT. Chondrocyte survival and material properties of hypothermically stored cartilage: an evaluation of tissue used for osteochondral allograft transplantation. Am J Sports Med. 2004 ; 32: 132-139
44. Williams RJ, Ranawat AS, Potter HG, Carter T, Warren RF. Fresh stored allografts for the treatment of osteochondral defects of the knee. J Bone Joint Surg Am. 2007 ; 89: 718-726