Intracerebroventricular 4-methylcatechol (4-MC) ameliorates chronic pain associated with depression-like behavior via induction of brain-derived neurotrophic factor (BDNF)

Cellular and Molecular Neurobiology

Volumn 32, Issue 6, 2012, Pages 971-977

  Fukuhara, Kayoko ^a,b   Ishikawa, Kozo ^a   Yasuda, Seiko ^a   Kishishita, Yusuke ^a   Kim, Hae Kyu ^c   Kakeda, Takahiro ^d   Yamamoto, Misa ^a   Norii, Takafumi ^b   Ishikawa, Toshizo ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Ube Frontier University   (Japan)

^c Pusan National University School of Medicine   (South Korea)

^d KAWASAKI UNIVERSITY OF MEDICAL WELFARE   (Japan)

Author keywords

4 Methylcatechol; BDNF; CCI; ERK1 2; Mood disorder; Neuropathic pain

Indexed keywords

4 METHYLCATECHOL; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR ANTIBODY; K 252A; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N (2,3 DIHYDROXYPROPOXY) 3,4 DIFLUORO 2 (2 FLUORO 4 IODOANILINO)BENZAMIDE; NALOXONE; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ARTICLE; CHRONIC CONSTRICTION INJURY; CHRONIC PAIN; CONTINUOUS INFUSION; CONTROLLED STUDY; DEPRESSION; DRUG ANTAGONISM; EMOTION; ENZYME ACTIVATION; FORCED SWIMMING TEST; HYPERALGESIA; IMMOBILIZATION; NONHUMAN; PAIN ASSESSMENT; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT;

ANALGESICS; ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; BENZAMIDES; BRAIN-DERIVED NEUROTROPHIC FACTOR; CATECHOLS; CHRONIC PAIN; DEPRESSION; DIPHENYLAMINE; INJECTIONS, INTRAVENTRICULAR; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RESTRAINT, PHYSICAL;

RATTUS;

EID: 84864648584     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-011-9782-2     Document Type: Article

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