Effect of short-term infusive dobutamine therapy on thyroid hormone profile and hemodynamic parameters in patients with acute worsening heart failure and low-triiodothyronine syndrome

Journal of Investigative Medicine

Volumn 60, Issue 6, 2012, Pages 907-910

  D'Aloia, Antonio ^a   Vizzardi, Enrico ^a   Bugatti, Silvia ^a   Rovetta, Riccardo ^a   Bonadei, Ivano ^a   Del Magro, Francesca ^a   Curnis, Antonio ^a   Dei Cas, Livio ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Dobutamine; Heart failure; Low triiodothyronine syndrome (LT3S)

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; DIURETIC AGENT; DOBUTAMINE; LIOTHYRONINE; NITRATE; THYROID HORMONE; THYROTROPIN; THYROXINE;

ACUTE HEART FAILURE; AGED; ARTICLE; CLINICAL EVALUATION; CONGESTIVE CARDIOMYOPATHY; DISEASE COURSE; DISEASE SEVERITY; DRUG EFFECT; HEART HEMODYNAMICS; HEART INDEX; HEART LEFT VENTRICLE EJECTION FRACTION; HEART RIGHT ATRIUM PRESSURE; HEART VENTRICLE FUNCTION; HOSPITALIZATION; HUMAN; ISCHEMIC CARDIOMYOPATHY; LOW TRIIODOTHYRONINE SYNDROME; LUNG CAPILLARY PRESSURE; MAJOR CLINICAL STUDY; PATHOPHYSIOLOGY; PROSPECTIVE STUDY; SHORT COURSE THERAPY; THYROID DISEASE; TRANSTHORACIC ECHOCARDIOGRAPHY;

EID: 84864623539     PISSN: 17088267     EISSN: 17088267     Source Type: Journal    
DOI: 10.2310/JIM.0b013e31825cec9c     Document Type: Article

References (22)

1. Wartofsky L, Barman KD. Alteration in thyroid function in patients with systemic illness: the "euthyroid sick syndrome". Endocr Rev. 1982;3:164-217.
2. Ascheim DD, Hryniewicz K. Thyroid hormone metabolism in patient with congestive heart failure: the low triiodothyronine state. Thyroid. 2002;12:511-515.
3. Haddad F, Baldwin KM, Morris G. Dietary effects on cardiac metabolism properties on rodents. J Mol Cell Cardiol. 1990;22:353-359.
4. Gustafson TA, Markham BE, Morkin E. Effects of thyroid hormone on actin and myosin heavy chain gene expression in cardiac and skeletal muscles of rat: measurement of mRNA content using synthetic oligonucleotide probes. Circ Res. 1986;59:353-359.
5. Pingitore A, Galli E. Acute effects of triiodothyronine (T3) replacement therapy in patients with chronic heart failure and low-T3 syndrome: a randomized, placebo-controlled study. J Clin Endocrinol Metab. 2008;93:1351-1358.
6. Schilling T, Grunding M, Strang CM, et al. Effects of dopexamine, dobutamine or dopamine on prolactin and thyreotropin serum concentrations in high-risk surgical patients. Intensive Care Med. 2004;30:1127-1133.
7. Van den Berghe G, de Zegher F, Vlasselaers D, et al. Thyrotropin- releasing hormone in critical illness: from a dopamine-dependent test to a strategy for increasing low serum triiodothyronine, prolactin, and growth hormone concentrations. Crit Care Med. 1996;24(4):590-595.
8. Lee E, Chen P, Rao H, et al. Effect of acute high dose dobutamine administration on serum thyrotrophin (TSH). Clin Endocrinol. 1999;50(4):487-492.
9. Grossman W. Evaluation of systolic and diastolic function of the myocardium. In: Grossman W, Baim DS, eds. Cardiac Catheterization, Angiography and Intervention. 4th ed. Philadelphia, PA: Lea and Febiger; 1994:52-79.
10. Hamilton MA, Warner Stevenson L, Luu M, et al. Altered thyroid hormone metabolism in advanced heart failure. JACC. 1990;16:91-95.
11. Mahdavi V, Izumo S, Nadal-Ginard B, et al. Developmental and hormonal regulation of sarcomeric myosin heavy chain gene family. Circ Res. 1987;60:804-814.
12. Pfister R. Strack N, Wielckens K, et al. The relationship and prognostic impact of low-T3 syndrome and NT-proBNP in cardiovascular patients. Int J Cardiol. 2010;144:187-190.
13. Iervasi G, Pingitore A, Landi P, et al. Low-T3 syndrome: a strong prognostic predictor of death in patients with heart disease. Circulation. 2003;107:708-713.
14. Pingitore A, Landi P, Taddie MC, et al. Triiodothyronine levels for risk stratification of patients with chronic heart failure. Am J Med. 2005;118:132-136.
15. Henderson KK, Danzi S, Paul JT, et al. Physiological replacement of T3 improves left ventricular function in an animal model of myocardial infarction-induced congestive heart failure. Circ Heart Fail. 2009;2(3):243-252.
16. Hamilton M, Lynne W. Safety and hemodynamic effects of intravenous triiodothyronine in advanced heart failure. Am J Cardiol. 1998;81:443-447.
17. Opasich C, Pacini F, Ambrosino N, et al. Sick euthyroid syndrome in patients with moderate-to-severe chronic heart failure. Eur Heart J. 1996;17: 860-866.
18. Sonnenblick EH, Frishman WH, LeJemtel TH. Dobutamine: a new synthetic cardioactive sympathetic amine. N Engl J Med. 1979;300(1):17-22.
19. Bakke J, Lawrence N, Roy S. Disappearance rate of exogenous thyroid-stimulating hormone (TSH) in man. J Clin Endocr Metab. 1961;22:352-363.
20. Al-Damluji S, Francis D. Activation of central alphal-adrenoceptors in humans stimulates secretion of prolactin and TSH, as well as ACTH. Am J Physiol. 1993;264: E208YE214.
21. Burrow G, May P, Spaulding SW, et al. TRH and dopamine interactions affecting pituitary hormone secretion. J Clin Endocr Metab. 1977;45:65-72.
22. Weber R, Tuttle R. Dobutamine. In: M. Goldberg, ed. Pharmacological and Biochemical of Drug Substances, Vol 1. Washington DC: American Pharmaceutical Association; 1977:109-124.