Serum biomarkers for predicting pregnancy outcome in women undergoing IVF: Human chorionic gonadotropin, progesterone, and inhibin A level at 11 days post-ET

Clinical and Experimental Reproductive Medicine

Volumn 39, Issue 1, 2012, Pages 28-32

  Kim, Jee Hyun ^a   Shin, Mi Sun ^a   Yi, Gwang ^a   Jee, Byung Chul ^a,b   Lee, Jung Ryeol ^a,b   Suh, Chang Suk ^a,b   Kim, Seok Hyun ^b,c  

^a Seoul National University Bundang Hospital   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c Seoul National University Hospital   (South Korea)

Author keywords

Chorionic Gonadotropin; Embryo Transfer; In Vitro Fertilization; Inhibins; Outcomes; Pregnancy; Progesterone

Indexed keywords

EID: 84864613243     PISSN: 22338233     EISSN: 22338241     Source Type: Journal    
DOI: 10.5653/cerm.2012.39.1.28     Document Type: Article

References (20)

1. Simón C, Landeras J, Zuzuarregui JL, Martín JC, Remohí J, Pellicer A. Early pregnancy losses in in vitro fertilization and oocyte donation. Fertil Steril 1999;72:1061-5.
2. Ochsenkühn R, Arzberger A, von Schönfeldt V, Engel J, Thaler CJ, Noss U. Predictive value of early serum beta-hCG levels after single blastocyst transfer. Acta Obstet Gynecol Scand 2009;88:1382-8.
3. Poikkeus P, Hiilesmaa V, Tiitinen A. Serum HCG 12 days after embryo transfer in predicting pregnancy outcome. Hum Reprod 2002;17:1901-5.
4. Urbancsek J, Hauzman E, Fedorcsák P, Halmos A, Dévényi N, Papp Z. Serum human chorionic gonadotropin measurements may predict pregnancy outcome and multiple gestation after in vitro fertilization. Fertil Steril 2002;78:540-2.
5. Papageorgiou TC, Leondires MP, Miller BT, Chang AS, Armstrong AB, Scott LA, et al. Human chorionic gonadotropin levels after blastocyst transfer are highly predictive of pregnancy outcome. Fertil Steril 2001;76:981-7.
6. Homan G, Brown S, Moran J, Homan S, Kerin J. Human chorionic gonadotropin as a predictor of outcome in assisted reproductive technology pregnancies. Fertil Steril 2000;73:270-4.
7. Treetampinich C, O'Connor AE, MacLachlan V, Groome NP, de Kretser DM. Maternal serum inhibin A concentrations in early pregnancy after IVF and embryo transfer reflect the corpus luteum contribution and pregnancy outcome. Hum Reprod 2000; 15:2028-32.
8. Hauzman E, Fedorcsák P, Klinga K, Papp Z, Rabe T, Strowitzki T, et al. Use of serum inhibin A and human chorionic gonadotropin measurements to predict the outcome of in vitro fertilization pregnancies. Fertil Steril 2004;81:66-72.
9. Ioannidis G, Sacks G, Reddy N, Seyani L, Margara R, Lavery S, et al. Day 14 maternal serum progesterone levels predict pregnancy outcome in IVF/ICSI treatment cycles: a prospective study. Hum Reprod 2005;20:741-6.
10. Elson J, Salim R, Tailor A, Banerjee S, Zosmer N, Jurkovic D. Prediction of early pregnancy viability in the absence of an ultrasonically detectable embryo. Ultrasound Obstet Gynecol 2003;21: 57-61.
11. Chetty M, Sawyer E, Dew T, Chapman AJ, Elson J. The use of novel biochemical markers in predicting spontaneously resolving 'pregnancies of unknown location'. Hum Reprod 2011;26:1318-23.
12. Yamoto M, Minami S, Nakano R. Immunohistochemical localization of inhibin subunits in human corpora lutea during menstrual cycle and pregnancy. J Clin Endocrinol Metab 1991;73:470-7.
13. Petraglia F, Garuti GC, Calza L, Roberts V, Giardino L, Genazzani AR, et al. Inhibin subunits in human placenta: localization and messenger ribonucleic acid levels during pregnancy. Am J Obstet Gynecol 1991;165:750-8.
14. Muttukrishna S, George L, Fowler PA, Groome NP, Knight PG. Measurement of serum concentrations of inhibin-A (alpha-beta A di-mer) during human pregnancy. Clin Endocrinol (Oxf) 1995;42: 391-7.
15. Muttukrishna S, Child TJ, Groome NP, Ledger WL. Source of circulating levels of inhibin A, pro alpha C-containing inhibins and activin A in early pregnancy. Hum Reprod 1997;12:1089-93.
16. Lockwood GM, Ledger WL, Barlow DH, Groome NP, Muttukrishna S. Measurement of inhibin and activin in early human pregnancy: demonstration of fetoplacental origin and role in prediction of early-pregnancy outcome. Biol Reprod 1997;57:1490-4.
17. Hauzman E, Murber A, Fancsovits P, Papp Z, Urbancsek J. Use of biochemical markers to predict the outcome of pregnancies conceived by in vitro fertilization. Orv Hetil 2006;147:1409-20.
18. Carmona F, Balasch J, Creus M, Fabregues F, Casamitjana R, Civico S, et al. Early hormonal markers of pregnancy outcome after in vitro fertilization and embryo transfer. J Assist Reprod Genet 2003;20:521-6.
19. Chen CD, Ho HN, Wu MY, Chao KH, Chen SU, Yang YS. Paired human chorionic gonadotrophin determinations for the prediction of pregnancy outcome in assisted reproduction. Hum Reprod 1997;12:2538-41.
20. Alahakoon TI, Crittenden J, Illingworth P. Value of single and paired serum human chorionic gonadotropin measurements in predicting outcome of in vitro fertilisation pregnancy. Aust N Z J Obstet Gynaecol 2004;44:57-61.