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Volumn 23, Issue , 2012, Pages 289-299

Design, characterisation and in vivo testing of a new, adjustable stiffness, external fixator for the rat femur

Author keywords

Bone healing; Dynamisation; External fixator; Mechanical stiffness; Mechanobiology; Small animal model

Indexed keywords

BIOMEDICAL AND DENTAL MATERIALS; POLYETHYLETHYLKETONE; TITANIUM; UNCLASSIFIED DRUG; ALLOY;

EID: 84864593833     PISSN: 14732262     EISSN: None     Source Type: Journal    
DOI: 10.22203/eCM.v023a22     Document Type: Article
Times cited : (26)

References (32)
  • 2
    • 58149269121 scopus 로고    scopus 로고
    • Early dynamization by reduced fixation stiffness does not improve fracture healing in a rat femoral osteotomy model
    • Claes L, Blakytny R, Gockelmann M, Schoen M, Ignatius A, Willie B (2009) Early dynamization by reduced fixation stiffness does not improve fracture healing in a rat femoral osteotomy model. J Orthop Res 27: 22-27.
    • (2009) J Orthop Res , vol.27 , pp. 22-27
    • Claes, L.1    Blakytny, R.2    Gockelmann, M.3    Schoen, M.4    Ignatius, A.5    Willie, B.6
  • 3
    • 79959513219 scopus 로고    scopus 로고
    • Late dynamization by reduced fixation stiffness enhances fracture healing in a rat femoral osteotomy model
    • Claes L, Blakytny R, Besse J, Bausewein C, Ignatius A, Willie B (2011) Late dynamization by reduced fixation stiffness enhances fracture healing in a rat femoral osteotomy model. J Orthop Trauma 25: 169-174.
    • (2011) J Orthop Trauma , vol.25 , pp. 169-174
    • Claes, L.1    Blakytny, R.2    Besse, J.3    Bausewein, C.4    Ignatius, A.5    Willie, B.6
  • 4
    • 0029113324 scopus 로고
    • Differential fore- and hindpaw force transmission in the walking rat
    • Clarke KA (1995) Differential fore- and hindpaw force transmission in the walking rat. Physiol Behav 58: 415-419.
    • (1995) Physiol Behav , vol.58 , pp. 415-419
    • Clarke, K.A.1
  • 5
    • 0036433325 scopus 로고    scopus 로고
    • The effect of recombinant human osteogenic protein-1 (bone morphogenetic protein-7) impregnation on allografts in a canine intercalary bone defect
    • Cullinane DM, Lietman SA, Inoue N, Deitz LW, Chao EY (2002) The effect of recombinant human osteogenic protein-1 (bone morphogenetic protein-7) impregnation on allografts in a canine intercalary bone defect. J Orthop Res 20: 1240-1245.
    • (2002) J Orthop Res , vol.20 , pp. 1240-1245
    • Cullinane, D.M.1    Lietman, S.A.2    Inoue, N.3    Deitz, L.W.4    Chao, E.Y.5
  • 6
    • 0043270436 scopus 로고    scopus 로고
    • Effects of the local mechanical environment on vertebrate tissue differentiation during repair: Does repair recapitulate development?
    • Cullinane DM, Salisbury KT, Alkhiary Y, Eisenberg S, Gerstenfeld L, Einhorn TA (2003) Effects of the local mechanical environment on vertebrate tissue differentiation during repair: does repair recapitulate development? J Exp Biol 206: 2459-2471.
    • (2003) J Exp Biol , vol.206 , pp. 2459-2471
    • Cullinane, D.M.1    Salisbury, K.T.2    Alkhiary, Y.3    Eisenberg, S.4    Gerstenfeld, L.5    Einhorn, T.A.6
  • 7
    • 43649083326 scopus 로고    scopus 로고
    • Microcomputed tomography imaging in a rat model of delayed union/non-union fracture
    • Dickson GR, Geddis C, Fazzalari N, Marsh D, Parkinson I (2008) Microcomputed tomography imaging in a rat model of delayed union/non-union fracture. J Orthop Res 26: 729-736.
    • (2008) J Orthop Res , vol.26 , pp. 729-736
    • Dickson, G.R.1    Geddis, C.2    Fazzalari, N.3    Marsh, D.4    Parkinson, I.5
  • 8
    • 0021347256 scopus 로고
    • The healing of segmental bone defects induced by demineralized bone matrix. A radiographic and biomechanical study
    • Einhorn TA, Lane JM, Burstein AH, Kopman CR, Vigorita VJ (1984) The healing of segmental bone defects induced by demineralized bone matrix. A radiographic and biomechanical study. J Bone Joint Surg Am 66: 274-279.
    • (1984) J Bone Joint Surg Am , vol.66 , pp. 274-279
    • Einhorn, T.A.1    Lane, J.M.2    Burstein, A.H.3    Kopman, C.R.4    Vigorita, V.J.5
  • 9
    • 0030175608 scopus 로고    scopus 로고
    • The influence of external fixators on fracture motion during simulated walking
    • Gardner TN, Evans M, Kenwright J (1996) The influence of external fixators on fracture motion during simulated walking. Med Eng Phys 18: 305-313.
    • (1996) Med Eng Phys , vol.18 , pp. 305-313
    • Gardner, T.N.1    Evans, M.2    Kenwright, J.3
  • 10
    • 70350764949 scopus 로고    scopus 로고
    • Ability of recombinant human bone morphogenetic protein 2 to enhance bone healing in the presence of tobramycin: Evaluation in a rat segmental defect model
    • Glatt V, Kwong FN, Park K, Parry N, Griffin D, Vrahas M, Evans CH, Harris M (2009) Ability of recombinant human bone morphogenetic protein 2 to enhance bone healing in the presence of tobramycin: evaluation in a rat segmental defect model. J Orthop Trauma 23: 693-701.
    • (2009) J Orthop Trauma , vol.23 , pp. 693-701
    • Glatt, V.1    Kwong, F.N.2    Park, K.3    Parry, N.4    Griffin, D.5    Vrahas, M.6    Evans, C.H.7    Harris, M.8
  • 12
    • 0025857773 scopus 로고
    • Comparative biomechanical studies of conventional and self-tapping cortical bone screws
    • Hess T, Hopf T, Fritsch E, Mittelmeier H (1991) [Comparative biomechanical studies of conventional and self-tapping cortical bone screws.] Z Orthop Grenz 129: 278-282.
    • (1991) Z Orthop Grenz , vol.129 , pp. 278-282
    • Hess, T.1    Hopf, T.2    Fritsch, E.3    Mittelmeier, H.4
  • 13
    • 77957851833 scopus 로고    scopus 로고
    • Mechanotransduction in bone repair and regeneration
    • Huang C, Ogawa R (2010) Mechanotransduction in bone repair and regeneration. FASEB J 24: 3625-3632.
    • (2010) FASEB J , vol.24 , pp. 3625-3632
    • Huang, C.1    Ogawa, R.2
  • 14
    • 24144470818 scopus 로고    scopus 로고
    • The critical size bony defect in a small animal for bone healing studies (II): Implant evolution and surgical technique on a rat's femur
    • Jager M, Sager M, Lensing-Hohn S, Krauspe R (2005) The critical size bony defect in a small animal for bone healing studies (II): implant evolution and surgical technique on a rat's femur. Biomed Tech (Berl) 50: 137-142.
    • (2005) Biomed Tech (Berl) , vol.50 , pp. 137-142
    • Jager, M.1    Sager, M.2    Lensing-Hohn, S.3    Krauspe, R.4
  • 15
    • 36749075662 scopus 로고    scopus 로고
    • An easily reproducible and biomechanically standardized model to investigate bone healing in rats, using external fixation
    • Kaspar K, Schell H, Toben D, Matziolis G, Bail HJ (2007) An easily reproducible and biomechanically standardized model to investigate bone healing in rats, using external fixation. Biomed Tech (Berl) 52: 383-390.
    • (2007) Biomed Tech (Berl) , vol.52 , pp. 383-390
    • Kaspar, K.1    Schell, H.2    Toben, D.3    Matziolis, G.4    Bail, H.J.5
  • 17
    • 1442280075 scopus 로고    scopus 로고
    • Effects of fracture fixation stability on ossification in healing fractures
    • Mark H, Nilsson A, Nannmark U, Rydevik B (2004) Effects of fracture fixation stability on ossification in healing fractures. Clin Orthop Relat Res 419: 245-250.
    • (2004) Clin Orthop Relat Res , vol.419 , pp. 245-250
    • Mark, H.1    Nilsson, A.2    Nannmark, U.3    Rydevik, B.4
  • 18
    • 22844446506 scopus 로고    scopus 로고
    • Torsional stiffness in healing fractures: Influence of ossification: An experimental study in rats
    • Mark H, Rydevik B (2005) Torsional stiffness in healing fractures: influence of ossification: an experimental study in rats. Acta Orthop 76: 428-433.
    • (2005) Acta Orthop , vol.76 , pp. 428-433
    • Mark, H.1    Rydevik, B.2
  • 21
    • 0036723976 scopus 로고    scopus 로고
    • Physiologic weight-bearing and consolidation of new bone in a rat model of distraction osteogenesis
    • Pacicca DM, Moore DC, Ehrlich MG (2002) Physiologic weight-bearing and consolidation of new bone in a rat model of distraction osteogenesis. J Pediatr Orthop 22: 652-659.
    • (2002) J Pediatr Orthop , vol.22 , pp. 652-659
    • Pacicca, D.M.1    Moore, D.C.2    Ehrlich, M.G.3
  • 22
    • 0035215805 scopus 로고    scopus 로고
    • Weight-bearing alters the expression of collagen types I and II, BMP 2/4 and osteocalcin in the early stages of distraction osteogenesis
    • Radomisli TE, Moore DC, Barrach HJ, Keeping HS, Ehrlich MG (2001) Weight-bearing alters the expression of collagen types I and II, BMP 2/4 and osteocalcin in the early stages of distraction osteogenesis. J Orthop Res 19: 1049-1056.
    • (2001) J Orthop Res , vol.19 , pp. 1049-1056
    • Radomisli, T.E.1    Moore, D.C.2    Barrach, H.J.3    Keeping, H.S.4    Ehrlich, M.G.5
  • 23
    • 0033386844 scopus 로고    scopus 로고
    • Marrow-derived progenitor cell injections enhance new bone formation during distraction
    • Richards M, Huibregtse BA, Caplan AI, Goulet JA, Goldstein SA (1999) Marrow-derived progenitor cell injections enhance new bone formation during distraction. J Orthop Res 17: 900-908.
    • (1999) J Orthop Res , vol.17 , pp. 900-908
    • Richards, M.1    Huibregtse, B.A.2    Caplan, A.I.3    Goulet, J.A.4    Goldstein, S.A.5
  • 25
    • 0032970328 scopus 로고    scopus 로고
    • Mechanical tension-stress induces expression of bone morphogenetic protein (BMP)-2 and BMP-4, but not BMP-6, BMP-7, and GDF-5 mRNA, during distraction osteogenesis
    • Sato M, Ochi T, Nakase T, Hirota S, Kitamura Y, Nomura S, Yasui N (1999) Mechanical tension-stress induces expression of bone morphogenetic protein (BMP)-2 and BMP-4, but not BMP-6, BMP-7, and GDF-5 mRNA, during distraction osteogenesis. J Bone Miner Res 14: 1084-1095.
    • (1999) J Bone Miner Res , vol.14 , pp. 1084-1095
    • Sato, M.1    Ochi, T.2    Nakase, T.3    Hirota, S.4    Kitamura, Y.5    Nomura, S.6    Yasui, N.7
  • 26
    • 1842832092 scopus 로고    scopus 로고
    • Intermittent parathyroid hormone (1-34) enhances mechanical strength and density of new bone after distraction osteogenesis in rats
    • Seebach C, Skripitz R, Andreassen TT, Aspenberg P (2004) Intermittent parathyroid hormone (1-34) enhances mechanical strength and density of new bone after distraction osteogenesis in rats. J Orthop Res 22: 472-478.
    • (2004) J Orthop Res , vol.22 , pp. 472-478
    • Seebach, C.1    Skripitz, R.2    Andreassen, T.T.3    Aspenberg, P.4
  • 28
    • 21344460246 scopus 로고    scopus 로고
    • Immunohistochemical study of vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2, -4 (BMP-2, -4) on lengthened rat femurs
    • Sojo K, Sawaki Y, Hattori H, Mizutani H, Ueda M (2005) Immunohistochemical study of vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2, -4 (BMP-2, -4) on lengthened rat femurs. J Craniomaxillofac Surg 33: 238-245.
    • (2005) J Craniomaxillofac Surg , vol.33 , pp. 238-245
    • Sojo, K.1    Sawaki, Y.2    Hattori, H.3    Mizutani, H.4    Ueda, M.5
  • 29
    • 49449101586 scopus 로고    scopus 로고
    • A new device to control mechanical environment in bone defect healing in rats
    • Strube P, Mehta M, Putzier M, Matziolis G, Perka C, Duda GN (2008) A new device to control mechanical environment in bone defect healing in rats. J Biomech 41: 2696-2702.
    • (2008) J Biomech , vol.41 , pp. 2696-2702
    • Strube, P.1    Mehta, M.2    Putzier, M.3    Matziolis, G.4    Perka, C.5    Duda, G.N.6
  • 31
    • 65249109767 scopus 로고    scopus 로고
    • Mechanical characterization of external fixator stiffness for a rat femoral fracture model
    • Willie B, Adkins K, Zheng X, Simon U, Claes L (2009) Mechanical characterization of external fixator stiffness for a rat femoral fracture model. J Orthop Res 27: 687-693.
    • (2009) J Orthop Res , vol.27 , pp. 687-693
    • Willie, B.1    Adkins, K.2    Zheng, X.3    Simon, U.4    Claes, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.