On the origin of Tremor in parkinson's disease

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Dovzhenok, Andrey ^a   Rubchinsky, Leonid L ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE;

ARTICLE; BASAL GANGLION; CALCIUM SIGNALING; DISEASE ASSOCIATION; DOPAMINE BRAIN LEVEL; DOPAMINE RELEASE; FEEDBACK SYSTEM; MOTOR ACTIVITY; NERVOUS SYSTEM CONDUCTANCE; NEUROANATOMY; NEUROMODULATION; OSCILLATION; PARKINSON DISEASE; SUBCORTEX; THALAMOCORTICAL TRACT; TREMOR;

BASAL GANGLIA; CALCIUM; CEREBELLAR CORTEX; DOPAMINERGIC NEURONS; ELECTROPHYSIOLOGICAL PROCESSES; FEEDBACK, PHYSIOLOGICAL; HUMANS; KINETICS; MODELS, NEUROLOGICAL; PARKINSON DISEASE; POTASSIUM; SYNAPSES; THALAMUS; TREMOR;

PARKINSONIA;

EID: 84864592247     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041598     Document Type: Article

References (71)

1. Gelb DJ, Oliver E, Gilman S,((1999)) Diagnostic Criteria for Parkinson Disease. Arch Neurol 56:: 33--39.
2. Lenz F, Kwan H, Martin R, Tasker RR, Dostrovsky JO, et al.((1994)) Single unit analysis of the human ventral thalamic nuclear group. Tremor-related activity in functionally identified cells. Brain 117:: 531--543.
3. Elble RJ, Koller WG (1990) Tremor. Baltimore, MD: John Hopkins University Press.
4. Deuschl G, Raethjen J, Baron R, Lindemann M, Wilms H, et al.((2000)) The pathophysiology of parkinsonian tremor: a review. J Neurol 247 (Suppl 5): V33--V48.
5. Rubchinsky LL, Kuznetsov AS, Wheelock VL, Sigvardt KA (2007) Tremor. Scholarpedia 2(10): 1379. Available: http://www.scholarpedia.org/article/Tremor. Accessed 2012 March 28.
6. Jellinger KA,((1999)) Post mortem studies in Parkinson's disease: is it possible to detect brain areas for specific symptoms? J Neural Transm. Suppl 56pp. 1--29.
7. Rivlin-Etzion M, Marmor O, Heimer G, Raz A, Nini A, et al.((2006)) Basal ganglia oscillations and pathophysiology of movement disorders. Curr Opin Neurobiol 16:: 629--637.
8. Moran A, Bergman H, Israel Z, Bar-Gad I,((2008)) Subthalamic nucleus functional organization revealed by parkinsonian neuronal oscillations and synchrony. Brain 131:: 3395--3409.
9. Weinberger M, Hutchison WD, Lozano AM, Hodaie M, Dostrovsky JO,((2009)) Increased gamma oscillatory activity in the subthalamic nucleus during tremor in Parkinson's disease patients. J Neurophysiol 101:: 789--802.
10. Llinas R (1984) Rebound excitation as the physiological basis for tremor: a biophysical study of the oscillatory properties of mammalian central neurons in vitro. In: Finley LJ, Capildeo R, editors. Movement Disorders, Tremor. Macmillan, London. 339-351.
11. Guehl D, Pessiglione M, François C, Yelnik J, Hirsch EC, et al.((2003)) Tremor-related activity of neurons in the 'motor' thalamus: changes in firing rate and pattern in the MPTP vervet model of parkinsonism. Eur J Neurosci 17:: 2388--2400.
12. Pare D, Curro'Dossi R, Steriade M,((1990)) Neuronal basis of the parkinsonian resting tremor: a hypothesis and its implications for treatment. Neuroscience 35:: 217--226.
13. Wichmann T, DeLong MR,((1999)) Oscillations in the basal ganglia. Nature 400:: 621--622.
14. Zirh TA, Lenz FA, Reich SG, Dougherty PM,((1998)) Patterns of bursting occurring in thalamic cells during parkinsonian tremor. Neuroscience 83:: 107--121.
15. Raethjen J, Govindan RB, Muthuraman M, Kopper F, Volkmann J, et al.((2009)) Cortical correlates of the basic and first harmonic frequency of Parkinsonian tremor. Clin Neurophysiol 120:: 1866--1872.
16. Volkmann J, Joliot M, Mogilner A, Ioannides AA, Lado F, et al.((1996)) Central motor loop oscillations in parkinsonian resting tremor revealed by magnetoencephalography. Neurology 46:: 1359--1370.
17. Timmermann L, Gross J, Dirks M, Volkmann J, Freund HJ, et al.((2003)) The cerebral oscillatory network of parkinsonian resting tremor. Brain 126:: 199--212.
18. Surmeier DJ, Mercer JN, Chan CS,((2005)) Autonomous pacemakers in the basal ganglia: who needs excitatory synapses anyway? Curr Opin Neurobiol 15:: 312--318.
19. Bevan MD, Atherton JF, Baufreton J,((2006)) Cellular principles underlying normal and pathological activity in the subthalamic nucleus. Curr Opin Neurobiol 16:: 621--628.
20. Levy R, Hutchison WD, Lozano AM, Dostrovsky JO,((2000)) High-frequency synchronization of neuronal activity in the subthalamic nucleus of parkinsonian patients with limb tremor. J Neurosci 20:: 7766--7775.
21. Hutchison WD, Lozano AM, Tasker RR, Lang AE, Dostrovsky JO,((2007)) Identification and characterization of neurons with tremor-frequency activity in human globus pallidus. Exp Brain Res 113:: 557--563.
22. Alvarez L, Macias R, Lopez G, Alvarez E, Pavon N, et al.((2005)) Bilateral subthalamotomy in Parkinson's disease: initial and long-term response. Brain 128:: 570--583.
23. Tarsy D, Vitek JL, Lozano AM,((2003)) Surgical Treatment of Parkinson's Disease and Other Movement Disorders. Totowa, NJ: Humana Press. 274 p.
24. Beiser DG, Houk JC,((1998)) Model of cortical-basal ganglionic processing: encoding the serial order of sensory events. J Neurophysiol 79:: 3168--3188.
25. Humphries MD, Stewart RD, Gurney KN,((2006)) A physiologically plausible model of action selection and oscillatory activity in the basal ganglia. J Neurosci 26:: 12921--12942.
26. Leblois A, Boraud T, Meissner W, Bergman H, Hansel D,((2006)) Competition between feedback loops underlies normal and pathological dynamics in the basal ganglia. J Neurosci 26:: 3567--3583.
27. Plenz D, Kitai ST,((1999)) A basal ganglia pacemaker formed by the subthalamic nucleus and external globus pallidus. Nature 400:: 677--682.
28. Terman D, Rubin JE, Yew AC, Wilson CJ,((2002)) Activity patterns in a model for subthalamopallidal network of basal ganglia. J Neurosci 22:: 2963--2976.
29. Wilson CJ,((2004)) Basal Ganglia. In: Shepherd GM, editor. The Synaptic Organization of the Brain. New York: Oxford University Press. pp. 361--413.
30. Smith Y, Raju DV, Pare JF, Sidibe M,((2004)) The thalamostriatal system: a highly specific network of the basal ganglia circuitry. Trends Neurosci 27:: 520--527.
31. Rubchinsky LL, Kopell N, Sigvardt KA,((2003)) Modeling facilitation and inhibition of competing motor programs in basal ganglia subthalamic nucleus- pallidal circuits. Proc Nat Acad Sci USA 100:: 14427--14432.
32. Rubin JE, Terman D,((2004)) High frequency stimulation of the subthalamic nucleus eliminates pathological thalamic rhythmicity in a computational model. J Comput Neurosci 16:: 211--235.
33. Best J, Park C, Terman D, Wilson C,((2007)) Transitions between irregular and rhythmic firing patterns in excitatory-inhibitory neuronal networks. J Comput Neurosci 23:: 217--235.
34. Izhikevich EM,((2007)) Dynamical Systems in Neuroscience: The Geometry of Excitability and Bursting. Cambridge, MA: The MIT Press. 441 p.
35. Romo R, Schultz W,((1992)) Role of primate basal ganglia and frontal cortex in the internal generation of movements. III Neuronal activity in the supplementary motor area. Exp Brain Res 91:: 396--407.
36. Guo Y, Rubin JE, McIntyre CC, Vitek JL, Terman D,((2008)) Thalamocortical relay fidelity varies across subthalamic nucleus deep brain stimulation protocols in a data-driven computational model. J Neurophysiol 99(3):: 1477--1492.
37. Elble RJ,((2002)) Tremor and dopamine agonists. Neurology 58:: S57--62.
38. Cooper AJ, Stanford IM,((2001)) Dopamine D2 receptor mediated presynaptic inhibition of striatopallidal GABA(A) IPSCs in vitro. Neuropharmacology 41:: 62--71.
39. Ogura M, Kita H,((2000)) Dynorphin exerts both postsynaptic and presynaptic effects in the Globus pallidus of the rat. J Neurophysiol 83:: 3366--3376.
40. Shen KZ, Zhu ZT, Munhall A, Johnson SW,((2003)) Dopamine receptor supersensitivity in rat subthalamus after 6-hydroxydopamine lesions. Eur J Neurosci 18:: 2967--2974.
41. Floran B, Floran L, Erlij D, Aceves J,((2004)) Dopamine D4 receptors inhibit depolarization-induced [3H]GABA release in the rat subthalamic nucleus. Eur J Pharmacol 498:: 97--102.
42. Cragg SJ, Baufreton J, Xue Y, Bolam JP, Bevan MD,((2004)) Synaptic release of dopamine in the subthalamic nucleus. Eur J Neurosci 20:: 1788--1802.
43. Shen KZ, Johnson SW,((2005)) Dopamine depletion alters responses to glutamate and GABA in the rat subthalamic nucleus. Neuroreport 16:: 171--174.
44. Baufreton J, Bevan MD,((2008)) D2-like dopamine receptor-mediated modulation of activity-dependent plasticity at GABAergic synapses in the subthalamic nucleus. J Physiol 586:: 2121--2142.
45. Shen KZ, Johnson SW,((2000)) Presynaptic dopamine D2 and muscarine M3 receptors inhibit excitatory and inhibitory transmission to rat subthalamic neurones in vitro. J Physiol. 525 (Pt 2):: 331--41.
46. Hernandez A, Ibanez-Sandoval O, Sierra A, Valdiosera R, Tapia D, et al.((2006)) Control of the subthalamic innervation of the rat globus pallidus by D2/3 and D4 dopamine receptors. J Neurophysiol 96:: 2877--2888.
47. Baufreton J, Zhu ZT, Garret M, Bioulac B, Johnson SW, et al.((2005)) Dopamine receptors set the pattern of activity generated in subthalamic neurons. FASEB J 19:: 1771--1777.
48. Ramanathan S, Tkatch T, Atherton JF, Wilson CJ, Bevan MD,((2008)) D2-like dopamine receptors modulate SKCa channel function in subthalamic nucleus neurons through inhibition of Cav2.2 channels. J Neurophysiol 99:: 442--459.
49. Hurtado JM, Rubchinsky LL, Sigvardt KA,((2004)) Statistical method for detection of phase locking episodes in neural oscillations. J Neurophysiol 91:: 1883--1898.
50. Pollock LJ, Davis L,((1930)) Muscle tone in parkinsonian states. Arch Neurol Psychiatry 23:: 303--319.
51. Rack PM, Ross HF,((1986)) The role of reflexes in the resting tremor of Parkinson's disease. Brain 109:: 115--141.
52. Chan CS, Glajch KE, Gertler TS, Guzman JN, Mercer JN, et al.((2011)) HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease. Nat Neurosci 14:: 85--92.
53. Mackey MC, Glass L,((1977)) Oscillations and chaos in physiological control system. Science 197:: 287--289.
54. Beuter A, Vasilakos K,((1995)) Tremor: Is Parkinson's disease a dynamical disease? Chaos 5:: 35--42.
55. Hassler R, Mundinger F, Riechert T,((1970)) Pathophysiology of tremor at rest derived from the correlation of anatomical and clinical data. Conf Neurol 32:: 79--87.
56. Burne JA,((1987)) Reflex origin of parkinsonian tremor. Exp Neurol 97:: 327--339.
57. Park C, Worth RM, Rubchinsky LL,((2011)) Neural dynamics in parkinsonian brain: the boundary between synchronized and nonsynchronized dynamics. Physical Review E 83,: 042901.
58. Kita H, Kita T,((2011)) Role of striatum in the Pause and Burst Generation in the Globus Pallidus of 6-OHDA-Treated Rats. Front Syst Neurosci 5:: 42.
59. Jones EG (2001) Morphology, nomenclature and connections of the thalamus and basal ganglia. In: Krauss JK, Jankovic J, Grossman RG, editors. Surgery for Parkinson's Disease and Movement Disorders. Philadelphia: Lippincott, Williams and Wilkins. 24-47.
60. Deuschl G, Bergman H,((2002)) Pathophysiology of nonparkinsonian tremors. Mov Disord 17 (Suppl 3): S41--S48.
61. Speelman JD, Schuurman R, de Bie RM, Esselink RA, Bosch DA,((2002)) Stereotactic neurosurgery for tremor. Mov Disord 17 (Suppl 3): S84--S88.
62. Raethjen J, Deuschl G,((2009)) Tremor. Curr Opin Neurol 22:: 400--405.
63. Bostan AC, Dum RP, Strick PL,((2010)) The basal ganglia communicate with the cerebellum. Proc Natl Acad Sci USA 107:: 8452--8456.
64. Miocinovic S, Parent M, Butson CR, Hahn PJ, Russo GS, et al.((2006)) Computational analysis of subthalamic nucleus and lenticular fasciculus activation during therapeutic deep brain stimulation. J Neurophysiol 96:: 1569--1580.
65. Lozano AM, Dostrovsky J, Chen R, Ashby P,((2002)) Deep brain stimulation for Parkinson's disease: disrupting the disruption. Lancet Neurol 1:: 225--231.
66. Grill WM, Snyder AN, Miocinovic S,((2004)) Deep brain stimulation creates an informational lesion of the stimulated nucleus. Neuroreport 15:: 1137--1140.
67. McIntyre CC, Mori S, Sherman DL, Thakor NV, Vitek JL,((2004)) Electric field and stimulating influence generated by deep brain stimulation of the subthalamic nucleus. Clin Neurophysiol 115:: 589--595.
68. Antonini A, Moeller JR, Nakamura T, Spetsieris P, Dhawan V, et al.((1998)) The metabolic anatomy of tremor in Parkinson's disease. Neurology 51:: 803--810.
69. Hurtado JM, Rubchinsky LL, Sigvardt KA, Wheelock VL, Pappas CTE,((2005)) Temporal evolution of oscillations and synchrony in GPi/muscle pairs in Parkinson's disease. J Neurophysiol 93:: 1569--1584.
70. Bergman H, Raz A, Feingold A, Nini A, Nelken I, et al.((1998)) Physiology of MPTP tremor. Mov Disord. (Suppl 3)pp. 29--34.
71. Wilms H, Sievers J, Deuschl G,((1999)) Animal models of tremor. Mov Disord 14:: 557--571.