메뉴 건너뛰기




Volumn 3, Issue 7, 2012, Pages 823-833

ROS-activated anticancer prodrugs: A new strategy for tumor-specific damage

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CHLORMETHINE; IMATINIB; PRODRUG; QUINONE DERIVATIVE; QUINONE METHIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

EID: 84864591550     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde.12.61     Document Type: Article
Times cited : (118)

References (84)
  • 1
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander ES, Linton LM, Birren B et al. Initial sequencing and analysis of the human genome. Nature 409, 860-921 (2001).
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1    Linton, L.M.2    Birren, B.3
  • 2
  • 3
    • 7244245762 scopus 로고    scopus 로고
    • Finishing the euchromatic sequence of the human genome
    • Collins FS, Lander ES, Rogers J et al. Finishing the euchromatic sequence of the human genome. Nature 431, 931-945 (2004).
    • (2004) Nature , vol.431 , pp. 931-945
    • Collins, F.S.1    Lander, E.S.2    Rogers, J.3
  • 4
    • 79951481957 scopus 로고    scopus 로고
    • Initial impact of the sequencing of the human genome
    • Lander ES. Initial impact of the sequencing of the human genome. Nature 470, 187-197 (2011).
    • (2011) Nature , vol.470 , pp. 187-197
    • Lander, E.S.1
  • 5
    • 79951475133 scopus 로고    scopus 로고
    • A decade's perspective on DNA sequencing technology
    • Mardis ER. A decade's perspective on DNA sequencing technology. Nature 470, 198-203 (2011).
    • (2011) Nature , vol.470 , pp. 198-203
    • Mardis, E.R.1
  • 6
    • 77956838065 scopus 로고    scopus 로고
    • Advances in understanding cancer genomes through second-generation sequencing
    • Meyerson M, Gabriel S, Getz G. Advances in understanding cancer genomes through second-generation sequencing. Nat. Rev. Genet. 11, 685-696 (2010).
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 685-696
    • Meyerson, M.1    Gabriel, S.2    Getz, G.3
  • 8
    • 84864599271 scopus 로고    scopus 로고
    • Small-molecule kinase inhibitors: From lab bench to clinic
    • Kenefick K. Small-molecule kinase inhibitors: From lab bench to clinic. Cell Notes 16, 26-29 (2006).
    • (2006) Cell Notes , vol.16 , pp. 26-29
    • Kenefick, K.1
  • 9
    • 33745489431 scopus 로고    scopus 로고
    • Oxidative and nitrative damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis
    • Kawanishi S, Hiraku Y, Pinlaor S, Ma N. Oxidative and nitrative damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis. Biol. Chem. 387(4), 365-372 (2006).
    • (2006) Biol. Chem. , vol.387 , Issue.4 , pp. 365-372
    • Kawanishi, S.1    Hiraku, Y.2    Pinlaor, S.3    Ma, N.4
  • 10
    • 0026021362 scopus 로고
    • Production of large amounts of hydrogen peroxide by human tumor cells
    • Szatrowski TP, Nathan CF. Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res. 51, 794-798 (1991).
    • (1991) Cancer Res. , vol.51 , pp. 794-798
    • Szatrowski, T.P.1    Nathan, C.F.2
  • 11
    • 1442360000 scopus 로고    scopus 로고
    • Intrinsic oxidative stress in cancer cells: A biochemical basis for therapeutic selectivity
    • Hileman EO, Liu J, Albitar M, Keating MJ, Huang P. Intrinsic oxidative stress in cancer cells: A biochemical basis for therapeutic selectivity. Cancer Chemother. Pharmacol. 53, 209-219 (2004).
    • (2004) Cancer Chemother. Pharmacol. , vol.53 , pp. 209-219
    • Hileman, E.O.1    Liu, J.2    Albitar, M.3    Keating, M.J.4    Huang, P.5
  • 13
    • 0035826733 scopus 로고    scopus 로고
    • Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1
    • Arnold RS, Shi J, Murad E et al. Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1. Proc. Natl Acad. Sci. USA 98, 5550-5555 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 5550-5555
    • Arnold, R.S.1    Shi, J.2    Murad, E.3
  • 14
    • 43249112094 scopus 로고    scopus 로고
    • ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis
    • Ishikawa K, Takenaga K, Akimoto M et al ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis. Science 320, 661-664 (2008).
    • (2008) Science , vol.320 , pp. 661-664
    • Ishikawa, K.1    Takenaga, K.2    Akimoto, M.3
  • 15
    • 64549096768 scopus 로고    scopus 로고
    • Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH:ubiquinone oxidoreductase (complex I) and production of reactive oxygen species
    • King MS, Sharpley MS, Hirst J. Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH:ubiquinone oxidoreductase (complex I) and production of reactive oxygen species. Biochemistry 48, 2053-2062 (2009).
    • (2009) Biochemistry , vol.48 , pp. 2053-2062
    • King, M.S.1    Sharpley, M.S.2    Hirst, J.3
  • 16
    • 0042705073 scopus 로고    scopus 로고
    • Reactive oxygen species mediate doxorubicin induced p53-independent apoptosis
    • Tsang WP, Chau SP, Kong SK, Kwok TT. Reactive oxygen species mediate doxorubicin induced p53-independent apoptosis. Life Sci. 73, 2047-2058 (2003).
    • (2003) Life Sci. , vol.73 , pp. 2047-2058
    • Tsang, W.P.1    Chau, S.P.2    Kong, S.K.3    Kwok, T.T.4
  • 17
    • 0036285034 scopus 로고    scopus 로고
    • C-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: A mechanism for oncogene-induced genetic instability
    • Vafa O, Wade M, Kern S et al. c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: A mechanism for oncogene-induced genetic instability. Mol. Cell 9, 1031-1044 (2002).
    • (2002) Mol. Cell , vol.9 , pp. 1031-1044
    • Vafa, O.1    Wade, M.2    Kern, S.3
  • 18
    • 79951812916 scopus 로고    scopus 로고
    • Telomere dysfunction induces metabolic and mitochondrial compromise
    • Sahin E, Colla S, Liesa M et al. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature 470, 359-65 (2011).
    • (2011) Nature , vol.470 , pp. 359-365
    • Sahin, E.1    Colla, S.2    Liesa, M.3
  • 19
    • 84859987864 scopus 로고    scopus 로고
    • Reactive oxygen species signaling in cancer: Comparison with aging
    • Afanas'ev I. Reactive oxygen species signaling in cancer: Comparison with aging. Aging Dis. 2, 219-230 (2011).
    • (2011) Aging Dis. , vol.2 , pp. 219-230
    • Afanas'ev, I.1
  • 20
    • 13244277942 scopus 로고    scopus 로고
    • Cuznsod deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life
    • Elchuri S, Oberley TD, Qi WB et al. CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life. Oncogene 24, 367-380 (2005).
    • (2005) Oncogene , vol.24 , pp. 367-380
    • Elchuri, S.1    Oberley, T.D.2    Qi, W.B.3
  • 21
    • 79957977169 scopus 로고    scopus 로고
    • Do reactive oxygen species play a role in myeloid leukemias
    • Hole PS, Darley RL, Tonks A Do reactive oxygen species play a role in myeloid leukemias? Blood 117, 5816-5826 (2011).
    • (2011) Blood , vol.117 , pp. 5816-5826
    • Hole, P.S.1    Darley, R.L.2    Tonks, A.3
  • 22
    • 0034699513 scopus 로고    scopus 로고
    • Superoxide dismutase as a target for the selective killing of cancer cells
    • Huang P, Feng L, Oldham EA, Keating MJ, Plunkett W. Superoxide dismutase as a target for the selective killing of cancer cells. Nature 407, 390-395 (2000).
    • (2000) Nature , vol.407 , pp. 390-395
    • Huang, P.1    Feng, L.2    Oldham, E.A.3    Keating, M.J.4    Plunkett, W.5
  • 23
    • 33748146888 scopus 로고    scopus 로고
    • Selective killing of oncogenically transformed cells through a ros-mediated mechanism by beta-phenylethyl isothiocyanate
    • Trachootham D, Zhou Y, Zhang H et al. Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate. Cancer Cell 10, 241-252 (2006).
    • (2006) Cancer Cell , vol.10 , pp. 241-252
    • Trachootham, D.1    Zhou, Y.2    Zhang, H.3
  • 24
    • 3042739537 scopus 로고    scopus 로고
    • Activation of antioxidant pathways in ras-mediated oncogenic transformation of human surface ovarian epithelial cells revealed by functional proteomics and mass spectrometry
    • Young TW, Mei FC, Yang G, Thompson- Lanza JA, Liu J, Cheng X. Activation of antioxidant pathways in ras-mediated oncogenic transformation of human surface ovarian epithelial cells revealed by functional proteomics and mass spectrometry. Cancer Res. 64, 4577-4584 (2004).
    • (2004) Cancer Res. , vol.64 , pp. 4577-4584
    • Young, T.W.1    Mei, F.C.2    Yang, G.3    Thompson- Lanza, J.A.4    Liu, J.5    Cheng, X.6
  • 25
    • 20844447150 scopus 로고    scopus 로고
    • Controlling tumor growth by modulating endogenous production of reactive oxygen species
    • Laurent A, Nicco C, Chéreau C et al. Controlling tumor growth by modulating endogenous production of reactive oxygen species. Cancer Res. 65, 948-956 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 948-956
    • Laurent, A.1    Nicco, C.2    Chéreau, C.3
  • 26
    • 18044364401 scopus 로고    scopus 로고
    • Differential modulation of normal and tumor cell proliferation by reactive oxygen species
    • Nicco C, Laurent A, Chereau C, Weill B, Batteux F. Differential modulation of normal and tumor cell proliferation by reactive oxygen species. Biomed Pharmacother. 59, 169-74 (2005).
    • (2005) Biomed Pharmacother. , vol.59 , pp. 169-174
    • Nicco, C.1    Laurent, A.2    Chereau, C.3    Weill, B.4    Batteux, F.5
  • 27
    • 0342327329 scopus 로고    scopus 로고
    • Adaptation to oxidative stress: Quinone-mediated protection of signaling in rat lung epithelial L2 cells
    • Choi J, Liu RM, Forman HJ. Adaptation to oxidative stress: Quinone-mediated protection of signaling in rat lung epithelial L2 cells. Biochem. Pharmacol. 53, 987-993 (1997).
    • (1997) Iochem. Pharmacol. , vol.53 , pp. 987-993
    • Choi, J.1    Liu, R.M.2    Forman, H.J.3
  • 28
    • 33750616552 scopus 로고    scopus 로고
    • Mitochondrial dysfunction, persistently elevated levels of reactive oxygen species and radiation-induced genomic instability: A review
    • Kim GJ, Chandrasekaran K, Morgan WF. Mitochondrial dysfunction, persistently elevated levels of reactive oxygen species and radiation-induced genomic instability: A review. Mutagenesis 21, 361-367 (2006).
    • (2006) Mutagenesis , vol.21 , pp. 361-367
    • Kim, G.J.1    Chandrasekaran, K.2    Morgan, W.F.3
  • 29
    • 58749084282 scopus 로고    scopus 로고
    • Nuclear oxidative damage correlates with poor survival in colorectal cancer
    • Sheridan J, Wang LM, Tosetto M et al. Nuclear oxidative damage correlates with poor survival in colorectal cancer. Br. J. Cancer 100, 381-388 (2009
    • (2009) Br. J. Cancer , vol.100 , pp. 381-388
    • Sheridan, J.1    Wang, L.M.2    Tosetto, M.3
  • 30
    • 0343776197 scopus 로고    scopus 로고
    • Role of reactive oxygen species in apoptosis: Implications for cancer therapy
    • Mates JM, Sanchez-Jimenez FM. Role of reactive oxygen species in apoptosis: Implications for cancer therapy. Int. J. Biochem. Cell. Biol. 32, 157-170 (2000).
    • (2000) Int. J. Biochem. Cell. Biol. , vol.32 , pp. 157-170
    • Mates, J.M.1    Sanchez-Jimenez, F.M.2
  • 31
    • 34447093423 scopus 로고    scopus 로고
    • Superoxide anion: Oncogenic reactive oxygen species
    • Pervaiz S, Clement MV. Superoxide anion: Oncogenic reactive oxygen species? Int. J. Biochem. Cell. Biol. 39, 1297-1304 (2007).
    • (2007) Int. Biochem. Cell. Biol. , vol.39 , pp. 1297-1304
    • Pervaiz, S.1    Clement, M.V.2
  • 32
    • 25444523184 scopus 로고    scopus 로고
    • Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity
    • Kong D, Park EJ, Stephen AG et al. Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity. Cancer Res. 65, 9047-9055 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 9047-9055
    • Kong, D.1    Park, E.J.2    Stephen, A.G.3
  • 33
    • 79959955993 scopus 로고    scopus 로고
    • Cancer therapeutic agents targeting hypoxia-inducible factor-1
    • Wang R, Zhou S, Li S. Cancer therapeutic agents targeting hypoxia-inducible factor-1. Curr. Med. Chem. 18, 3168-3189 (2011).
    • (2011) Curr. Med. Chem. , vol.18 , pp. 3168-3189
    • Wang, R.1    Zhou, S.2    Li, S.3
  • 34
    • 79952532412 scopus 로고    scopus 로고
    • Cancer epigenetics: Linking basic biology to clinical medicine
    • Tsai HC, Baylin SB. Cancer epigenetics: Linking basic biology to clinical medicine. Cell Res. 21, 502-517 (2011).
    • (2011) Cell Res. , vol.21 , pp. 502-517
    • Tsai, H.C.1    Baylin, S.B.2
  • 35
    • 81255162523 scopus 로고    scopus 로고
    • Oxidative damage targets complexes containing DNA methyltransferases SIRT1 and polycomb members to promoter CpG Islands
    • O'Hagan HM, Wang W, Sen S et al. Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands. Cancer Cell. 20, 606-619 (2011).
    • (2011) Cancer Cell. , vol.20 , pp. 606-619
    • O'Hagan, H.M.1    Wang, W.2    Sen, S.3
  • 36
    • 79953870540 scopus 로고    scopus 로고
    • Targeting hif1a eliminates cancer stem cells in hematological malignancies
    • Wang Y, Liu Y, Malek SN, Zheng P, Liu Y. Targeting HIF1a eliminates cancer stem cells in hematological malignancies. Cell Stem Cell. 8, 399-411 (2011).
    • (2011) Cell Stem. Cell. , vol.8 , pp. 399-411
    • Wang, Y.1    Liu, Y.2    Malek, S.N.3    Zheng, P.4    Liu, Y.5
  • 37
    • 35448982386 scopus 로고    scopus 로고
    • Dual effect of echinomycin on hypoxia-inducible factor-1 activity under normoxic and hypoxic conditions
    • Vlaminck B, Toffoli S, Ghislain B, Demazy C, Raes M, Michiels C. Dual effect of echinomycin on hypoxia-inducible factor-1 activity under normoxic and hypoxic conditions. FEBS J. 274, 5533-5542 (2007).
    • (2007) Febs J. , vol.274 , pp. 5533-5542
    • Vlaminck, B.1    Toffoli, S.2    Ghislain, B.3    Demazy, C.4    Raes, M.5    Michiels, C.6
  • 38
    • 0026718484 scopus 로고
    • Echinomycin (NSC 526417) in recurrent and metastatic nonsquamous cell carcinoma of the cervix. A Phase II trial of the gynecologic oncology group
    • Muss HB, Blessing JA, Hanjani P, Malfetano JH, Kemp GM, Webster K. Echinomycin (NSC 526417) in recurrent and metastatic nonsquamous cell carcinoma of the cervix. A Phase II trial of the gynecologic oncology group. Am. J. Clin. Oncol. 15, 363-364 (1992).
    • (1992) Am. J. Clin. Oncol. , vol.15 , pp. 363-364
    • Muss, H.B.1    Blessing, J.A.2    Hanjani, P.3    Malfetano, J.H.4    Kemp, G.M.5    Webster, K.6
  • 39
    • 0027132564 scopus 로고
    • Echinomycin in recurrent and metastatic endometrial carcinoma
    • A Phase II trial of the Gynecologic Oncology Group
    • Muss HB, Blessing JA, DuBeshter B. Echinomycin in recurrent and metastatic endometrial carcinoma. A Phase II trial of the Gynecologic Oncology Group. Am. J. Clin. Oncol. 16, 492-493 (1993).
    • (1993) Am. J. Clin. Oncol. , vol.16 , pp. 492-493
    • Muss, H.B.1    Blessing, J.A.2    DuBeshter, B.3
  • 40
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumor hypoxia in cancer treatment
    • Brown JM, Wilson WR. Exploiting tumor hypoxia in cancer treatment. Nat. Rev. Cancer 4, 437-447 (2004).
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 41
    • 80051628334 scopus 로고    scopus 로고
    • Pronounced hypoxia in models of murine and human leukemia: High efficacy of hypoxia-activated prodrug PR-104
    • Benito J, Shi Y, Szymanska B et al. Pronounced hypoxia in models of murine and human leukemia: High efficacy of hypoxia-activated prodrug PR-104. PloS ONE 6, e23108 (2011).
    • (2011) Plos One , vol.6
    • Benito, J.1    Shi, Y.2    Szymanska, B.3
  • 42
    • 34447122556 scopus 로고    scopus 로고
    • Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA cross-linking agent PR-104
    • Patterson AV, Ferry DM, Edmunds SJ et al. Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA cross-linking agent PR-104. Clin. Cancer Res. 13, 3922-3932 (2007)
    • (2007) Clin. Cancer Res. , vol.13 , pp. 3922-3932
    • Patterson, A.V.1    Ferry, D.M.2    Edmunds, S.J.3
  • 43
    • 58149105356 scopus 로고    scopus 로고
    • Cancer cell killing via ROS: To increase or decrease, that is the question
    • Wang J, Yi J. Cancer cell killing via ROS:T o increase or decrease, that is the question. Cancer Biol. Ther. 7, 1875-1884 (2008).
    • (2008) Cancer Biol. Ther. , vol.7 , pp. 1875-1884
    • Wang, J.1    Yi, J.2
  • 44
    • 33144488485 scopus 로고    scopus 로고
    • Improvement of the therapeutic index of anticancer drugs by the superoxide dismutase mimic mangafodipir
    • Alexandre J, Nicco C, Chéreau C. Improvement of the therapeutic index of anticancer drugs by the superoxide dismutase mimic mangafodipir. J. Natl Cancer Inst. 98, 236-244 (2006).
    • (2006) J. Natl Cancer Inst. , vol.98 , pp. 236-244
    • Alexandre, J.1    Nicco, C.2    Chéreau, C.3
  • 45
    • 0141509869 scopus 로고    scopus 로고
    • Inhibition of mitochondrial respiration: A novel strategy to enhance drug-induced apoptosis in human cells by a reactive oxygen species-mediated mechanism
    • Pelicano H, Feng L, Zhou Y et al. Inhibition of mitochondrial respiration: A novel strategy to enhance drug-induced apoptosis in human cells by a reactive oxygen species-mediated mechanism. J. Biol. Chem. 278, 37832-37839 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 37832-37839
    • Pelicano, H.1    Feng, L.2    Zhou, Y.3
  • 46
    • 67650071137 scopus 로고    scopus 로고
    • Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic appoach
    • Trachootham, D, Alexandre J, Huang P. Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic appoach? Nat. Rev. Drug. Discov. 8, 579-591 (2009).
    • (2009) Nat. Rev. Drug. Discov. , vol.8 , pp. 579-591
    • Trachootham, D.1    Alexandre, J.2    Huang, P.3
  • 47
    • 2942593991 scopus 로고    scopus 로고
    • Ros stress in cancer cells and the therapeutic implications
    • Pelicano H, Carney D, Huang P. ROS stress in cancer cells and the therapeutic implications. Drug Resist. Update 7, 97-110 (2004).
    • (2004) Drug Resist. Update , vol.7 , pp. 97-110
    • Pelicano, H.1    Carney, D.2    Huang, P.3
  • 48
    • 34248396033 scopus 로고    scopus 로고
    • Dual role of hydrogen peroxide in cancer: Possible relevance to cancer chemoprevention and therapy
    • Lopez-Lazaro M. Dual role of hydrogen peroxide in cancer: Possible relevance to cancer chemoprevention and therapy. Cancer Lett. 252, 1-8 (2007).
    • (2007) Cancer Lett. , vol.252 , pp. 1-8
    • Lopez-Lazaro, M.1
  • 49
    • 64149087422 scopus 로고    scopus 로고
    • Therapeutic strategies by modulating oxygen stress in cancer and inflammation
    • Fang J, Seki T, Maeda H. Therapeutic strategies by modulating oxygen stress in cancer and inflammation. Adv. Drug Deliv. Rev. 61, 290-302 (2009).
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 290-302
    • Fang, J.1    Seki, T.2    Maeda, H.3
  • 50
    • 33748165596 scopus 로고    scopus 로고
    • Reactive oxygen species in cancer cells: Live by the sword die by the sword
    • Schumacker PT. Reactive oxygen species in cancer cells: Live by the sword, die by the sword. Cancer Cell. 10, 175-176 (2006).
    • (2006) Cancer Cell. , vol.10 , pp. 175-176
    • Schumacker, P.T.1
  • 51
    • 0033568238 scopus 로고    scopus 로고
    • Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway
    • Jing Y, Dai J, Chalmers-Redman RM, Tatton WG, Waxman S. Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway. Blood 94, 2102-2111 (1999).
    • (1999) Blood , vol.94 , pp. 2102-2111
    • Jing, Y.1    Dai, J.2    Chalmers-Redman, R.M.3    Tatton, W.G.4    Waxman, S.5
  • 52
    • 0031011174 scopus 로고    scopus 로고
    • Role of reactive oxygen species in cis-diclorodiammineplatinum-induced cytotoxicity on bladder cancer cells
    • Miyajima A, Nakashima J, Yoshioka K, Tachibana M, Tazaki H, Murai M. Role of reactive oxygen species in cis-diclorodiammineplatinum-induced cytotoxicity on bladder cancer cells. Br. J. Cancer 76, 206-210 (1997).
    • (1997) Br. J. Cancer , vol.76 , pp. 206-210
    • Miyajima, A.1    Nakashima, J.2    Yoshioka, K.3    Tachibana, M.4    Tazaki, H.5    Murai, M.6
  • 53
    • 82755166890 scopus 로고    scopus 로고
    • Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses
    • Anastasious D, Poulogiannis G, Asara JM et al. Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. Science 334, 1278-1283 (2011).
    • (2011) Science , vol.334 , pp. 1278-1283
    • Anastasious, D.1    Poulogiannis, G.2    Asara, J.M.3
  • 54
    • 0035874967 scopus 로고    scopus 로고
    • Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins
    • Lee SH, Oe T, Blair IA. Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins. Science 292, 2083-2086 (2001).
    • (2001) Science , vol.292 , pp. 2083-2086
    • Lee, S.H.1    Oe, T.2    Blair, I.A.3
  • 55
    • 33845472110 scopus 로고    scopus 로고
    • Preventive effects of vitamin c on carcinogenesis
    • Lee KW, Lee HJ, Kang KS, Lee CY. Preventive effects of vitamin C on carcinogenesis. Lancet 359, 172 (2002).
    • (2002) Lancet , vol.359 , pp. 172
    • Lee, K.W.1    Lee, H.J.2    Kang, K.S.3    Lee, C.Y.4
  • 56
    • 19344368071 scopus 로고    scopus 로고
    • Chemopreventive and therapeutic effects of curcumin
    • Duvoix A, Blasius R, Delhalle S et al. Chemopreventive and therapeutic effects of curcumin. Cancer Lett. 223, 181-190 (2005).
    • (2005) Cancer Lett. , vol.223 , pp. 181-190
    • Duvoix, A.1    Blasius, R.2    Delhalle, S.3
  • 57
    • 0034176645 scopus 로고    scopus 로고
    • The antioxidant paradox
    • Halliwell B. The antioxidant paradox. Lancet 355, 1179-1180 (2000).
    • (2000) Lancet , vol.355 , pp. 1179-1180
    • Halliwell, B.1
  • 58
    • 33646517942 scopus 로고    scopus 로고
    • Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo
    • Alexandre J, Batteux F, Nicco C et al. Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo. Int. J. Cancer 119, 41-48 (2006).
    • (2006) Int. J. Cancer , vol.119 , pp. 41-48
    • Alexandre, J.1    Batteux, F.2    Nicco, C.3
  • 59
    • 37849018320 scopus 로고    scopus 로고
    • Antioxidants block proteasome inhibitor function in endometrial carcinoma cells
    • Llobet D, Eritja N, Encinas M et al. Antioxidants block proteasome inhibitor function in endometrial carcinoma cells. Anticancer Drugs 19, 115-124 (2008).
    • (2008) Anticancer Drugs , vol.19 , pp. 115-124
    • Llobet, D.1    Eritja, N.2    Encinas, M.3
  • 60
    • 33144466181 scopus 로고    scopus 로고
    • Redox modulation of chemotherapy-induced tumor cell killing and normal tissue toxicity
    • Doroshow JH. Redox modulation of chemotherapy-induced tumor cell killing and normal tissue toxicity. J. Natl. Cancer Inst. 98, 223-225 (2006).
    • (2006) J. Natl. Cancer Inst. , vol.98 , pp. 223-225
    • Doroshow, J.H.1
  • 61
    • 0035415493 scopus 로고    scopus 로고
    • Prodrugs strategies in cancer therapy
    • Denny WA. Prodrugs strategies in cancer therapy. Eur. J. Med. Chem. 36, 577-595 (2001).
    • (2001) Eur. J. Med. Chem. , vol.36 , pp. 577-595
    • Denny, W.A.1
  • 62
    • 79960427057 scopus 로고    scopus 로고
    • Selective killing of cancer cells by a small molecule targeting the stress response to ros
    • Raj L, Ide T, Gurkar AU et al. Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature 475, 231-234.
    • Nature , vol.475 , pp. 231-234
    • Raj, L.1    Ide, T.2    Gurkar, A.U.3
  • 63
    • 77957903553 scopus 로고    scopus 로고
    • Synthesis and selective anticancer activity of organochalcogen based redox catalysts
    • Doering M, Ba LA, Lilienthal N et al. Synthesis and selective anticancer activity of organochalcogen based redox catalysts. J. Med. Chem. 53, 6954-6963 (2010).
    • (2010) J. Med. Chem. , vol.53 , pp. 6954-6963
    • Doering, M.1    Ba, L.A.2    Lilienthal, N.3
  • 64
    • 77951081423 scopus 로고    scopus 로고
    • Chemistry and biology of deoxynyboquinone, a potent inducer of cancer cell death
    • Bair JS, Palchaudhuri R, Hergenrother PJ. Chemistry and biology of deoxynyboquinone, a potent inducer of cancer cell death, J. Am. Chem. Soc. 132, 5469-5478 (2010).
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 5469-5478
    • Bair, J.S.1    Palchaudhuri, R.2    Hergenrother, P.J.3
  • 65
    • 77956598957 scopus 로고    scopus 로고
    • Hydrogen peroxide activated matrix metalloproteinase inhibitors: A prodrug approach
    • Major Jourden JL, Cohen SM. Hydrogen peroxide activated matrix metalloproteinase inhibitors: A prodrug approach. Angew. Chem. Int. Ed. 49, 6795-6797 (2010).
    • (2010) Angew. Chem. Int. Ed. , vol.49 , pp. 6795-6797
    • Major Jourden, J.L.1    Cohen, S.M.2
  • 66
    • 82555170608 scopus 로고    scopus 로고
    • Peroxide inducible DNA cross-linking agents:T argeted anticancer prodrugs
    • Kuang Y, Balakrishnan K, Gandhi V, Peng X. Hydrogen peroxide inducible DNA cross-linking agents:T argeted anticancer prodrugs. J. Am. Chem. Soc. 133, 19278-19231 (2011).
    • (2011) J. Am. Chem. Soc. , vol.133 , pp. 19278-19231
    • Kuang, Y.1    Balakrishnan, K.2    Gandhi, V.3    Peng, X.4
  • 67
    • 84856400292 scopus 로고    scopus 로고
    • Aminoferrocene-based prodrugs activated by reactive oxygen species
    • Hagen H, Marzenell P, Jentzsch E et al. Aminoferrocene-based prodrugs activated by reactive oxygen species. J. Med. Chem. 55(2), 924-934 (2012).
    • (2012) J. Med. Chem. , vol.55 , Issue.2 , pp. 924-934
    • Hagen, H.1    Marzenell, P.2    Jentzsch, E.3
  • 68
    • 79955034398 scopus 로고    scopus 로고
    • Oxidatively activated DNA-modifying agents for selective cytotoxicity
    • Li G, Bell T, Merino EJ. Oxidatively activated DNA-modifying agents for selective cytotoxicity. Chem. Med. Chem. 6, 869-875 (2011).
    • (2011) Chem. Med. Chem. , vol.6 , pp. 869-875
    • Li, G.1    Bell, T.2    Merino, E.J.3
  • 69
    • 29544436942 scopus 로고    scopus 로고
    • Ferrocene-mediated proton-coupled electron transfer in a series of ferrocifen-typed breast cancer drug candidates
    • Hillard E, Vessieres A, Thouin L, Jaouen G, Amatore C. Ferrocene-mediated proton-coupled electron transfer in a series of ferrocifen-typed breast cancer drug candidates. Angew. Chem. Int. Ed. 45, 285-290 (2006).
    • (2006) Angew. Chem. Int. Ed. , vol.45 , pp. 285-290
    • Hillard, E.1    Vessieres, A.2    Thouin, L.3    Jaouen, G.4    Amatore, C.5
  • 70
    • 20444389353 scopus 로고    scopus 로고
    • Modification of the estrogenic properties of diphenols by the incorporation of ferrocene generation of antiproliferative effects in vitro
    • Vessieres A, Top S, Pigeon P et al. Modification of the estrogenic properties of diphenols by the incorporation of ferrocene. Generation of antiproliferative effects in vitro. J. Med. Chem. 48, 3937-3940 (2005).
    • (2005) J. Med. Chem. , vol.48 , pp. 3937-3940
    • Vessieres, A.1    Top, S.2    Pigeon, P.3
  • 71
    • 70449555098 scopus 로고    scopus 로고
    • Ferrocenyl quinone methides as strong antipfoliferative agents: Formation by metabolic and chemical oxidation of ferrocenyl phenols. Angew
    • Hamels D, Dansette PM, Hillard EA et al. Ferrocenyl quinone methides as strong antipfoliferative agents: Formation by metabolic and chemical oxidation of ferrocenyl phenols. Angew. Chem. Int. Ed. 48, 9124-9126 (2009).
    • (2009) Chem. Int. Ed. , vol.48 , pp. 9124-9126
    • Hamels, D.1    Dansette, P.M.2    Hillard, E.A.3
  • 72
    • 84861159405 scopus 로고    scopus 로고
    • Deciphering the activation sequence of ferrociphenol anticancer drug candidates. Chem
    • Messina P, Labbe E, Buriez O et al. Deciphering the activation sequence of ferrociphenol anticancer drug candidates. Chem. Eur. J. 18(21), 6581-6587 (2012).
    • (2012) Eur. J. , vol.18 , Issue.21 , pp. 6581-6587
    • Messina, P.1    Labbe, E.2    Buriez, O.3
  • 73
    • 0037724313 scopus 로고
    • Electrophilic displacement reactions. IX Effects of substituents on rates of reactions between hydrogen peroxide and benzeneboronic acid
    • Kuivila HG, Armour AG. Electrophilic displacement reactions. IX. Effects of substituents on rates of reactions between hydrogen peroxide and benzeneboronic acid. J. Am. Chem. Soc. 79, 5659-5662 (1957).
    • (1957) J. Am. Chem. Soc. , vol.79 , pp. 5659-5662
    • Kuivila, H.G.1    Armour, A.G.2
  • 74
    • 85157234778 scopus 로고    scopus 로고
    • Boronic Acids Hall DG (Ed.), Weinheim, Germany
    • Yang WQ, Gao X, Wang BH. Boronic Acids Hall DG (Ed.). Wiley-VCH, Weinheim, Germany, 481-512 (2005).
    • (2005) Wiley-VCH , pp. 481-512
    • Yang, W.Q.1    Gao, X.2    Wang, B.H.3
  • 75
    • 48249118740 scopus 로고    scopus 로고
    • A targetable fluorescent probe for imaging hydrogen peroxide in the mitochondria of living cells. J
    • Dickinson BC, Chang CJ. A targetable fluorescent probe for imaging hydrogen peroxide in the mitochondria of living cells. J. Am. Chem. Soc. 130, 9638-9639 (2008).
    • (2008) Am. Chem. Soc. , vol.130 , pp. 9638-9639
    • Dickinson, B.C.1    Chang, C.J.2
  • 76
    • 28444495141 scopus 로고    scopus 로고
    • Boronate-based fluorescent probes for imaging cellular hydrogen peroxide. J
    • Miller EW, Albers AE, Pralle A, Isacoff EY, Chang CJ. Boronate-based fluorescent probes for imaging cellular hydrogen peroxide. J. Am. Chem. Soc. 127, 16652-16659 (2005).
    • (2005) Am. Chem. Soc. , vol.127 , pp. 16652-16659
    • Miller, E.W.1    Albers, A.E.2    Pralle, A.3    Isacoff, E.Y.4    Chang, C.J.5
  • 77
    • 34247255302 scopus 로고    scopus 로고
    • Moleaular imaging of hydrogen peroxide produced for cell signalling. Nat
    • Miller EW, Tulyathan O, Isacoff EY, Chang CJ. Moleaular imaging of hydrogen peroxide produced for cell signalling. Nat. Chem. Biol. 3, 263-267 (2007).
    • (2007) Chem. Biol. , vol.3 , pp. 263-267
    • Miller, E.W.1    Tulyathan, O.2    Isacoff, E.Y.3    Chang, C.J.4
  • 78
    • 41849149664 scopus 로고    scopus 로고
    • An ICT-based approach to ratiometric fluorescence imaging of hydrogen peroxide produced in living cells
    • Srikun D, Miller EW, Domaille DW, Chang CJ. An ICT-based approach to ratiometric fluorescence imaging of hydrogen peroxide produced in living cells. J. Am. Chem. Soc. 130, 4596-4597 (2008).
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 4596-4597
    • Srikun, D.1    Miller, E.W.2    Domaille, D.W.3    Chang, C.J.4
  • 79
    • 23844551612 scopus 로고    scopus 로고
    • Glutathione peroxidase, glutathione-S-transferase, catalase, xanthine oxidase, Cu-Zn superoxide dismutase activities, total glutathione, nitric oxide, and malondialdehyde levels in erythrocytes of patients with small cell and non-small cell lung cancer
    • Kaynar H, Meral M, Turhanb H, Kelesc M, Celikb G, Akcayb F. Glutathione peroxidase, glutathione-S-transferase, catalase, xanthine oxidase, Cu-Zn superoxide dismutase activities, total glutathione, nitric oxide, and malondialdehyde levels in erythrocytes of patients with small cell and non-small cell lung cancer. Cancer Lett. 227, 133-139 (2005).
    • (2005) Cancer Lett. , vol.227 , pp. 133-139
    • Kaynar, H.1    Meral, M.2    Turhanb, H.3    Kelesc, M.4    Celikb, G.5    Akcayb, F.6
  • 80
    • 41849113037 scopus 로고    scopus 로고
    • Measurement of oxidative stress and antioxidant status in acute lymphoblastic leukemia patients
    • Battisti V, Maders LDK, Bagatini MD et al. Measurement of oxidative stress and antioxidant status in acute lymphoblastic leukemia patients. Clin. Biochem. 41, 511-518 (2008).
    • (2008) Clin. Biochem. , vol.41 , pp. 511-518
    • Battisti, V.1    Maders, L.D.K.2    Bagatini, M.D.3
  • 81
    • 84862806824 scopus 로고    scopus 로고
    • Status of oxidative stress in patients with renal cell carcinoma
    • Ganesamoni R, Bhattacharyya S, Kumar S et al. Status of oxidative stress in patients with renal cell carcinoma. J. Urol. 187, 1172-1176 (2012).
    • (2012) J. Urol. , vol.187 , pp. 1172-1176
    • Ganesamoni, R.1    Bhattacharyya, S.2    Kumar, S.3
  • 82
    • 0037926836 scopus 로고    scopus 로고
    • Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents
    • Zhou Y, Hileman EO, Plunkett W, Keating MJ, Huang P. Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents. Blood 101, 4098-4104 (2003).
    • (2003) Blood , vol.101 , pp. 4098-4104
    • Zhou, Y.1    Hileman, E.O.2    Plunkett, W.3    Keating, M.J.4    Huang, P.5
  • 83
    • 84858958604 scopus 로고    scopus 로고
    • ROS-inducible DNA cross-linking agent as a new anticancer prodrug building block
    • Cao S, Wang Y, Peng X. ROS-inducible DNA cross-linking agent as a new anticancer prodrug building block. Chem. Eur. J. 18, 3850-3854 (2012).
    • (2012) Chem. Eur. J. , vol.18 , pp. 3850-3854
    • Cao, S.1    Wang, Y.2    Peng, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.