Blood biomarkers and measures of pulmonary function-A study from the Swedish twin registry

Respiratory Medicine

Volumn 106, Issue 9, 2012, Pages 1250-1257

  Engström, Gunnar ^a,b   Lindberg, Claes ^a   Gerhardsson De Verdier, Maria ^a   Nihlén, Ulf ^a,c   Anderson, Martin ^d   Svartengren, Magnus ^e   Forsman Semb, Kristina ^a,f  

^a ASTRAZENECA R AND D   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c LUND UNIVERSITY   (Sweden)

^d STOCKHOLM SÖDER HOSPITAL   (Sweden)

^e KAROLINSKA INSTITUTE   (Sweden)

^f Truly Translational Sweden AB   (Sweden)

Author keywords

Biomarkers; COPD; Inflammation; Lung function

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; CARBON MONOXIDE; CLARA CELL PROTEIN; CLARA CELL PROTEIN 16; DESMOSINE; GELATINASE B; INTERLEUKIN 8; PLASMINOGEN ACTIVATOR INHIBITOR 1; SCATTER FACTOR; SURFACTANT PROTEIN D; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CORRELATION ANALYSIS; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; LUNG DIFFUSION CAPACITY; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; REGISTER; RESIDUAL VOLUME; SWEDEN; TOTAL LUNG CAPACITY; TWINS;

BIOLOGICAL MARKERS; BODY MASS INDEX; CROSS-SECTIONAL STUDIES; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; REGISTRIES; VITAL CAPACITY;

EID: 84864586574     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2012.05.004     Document Type: Article

References (30)

1. J. Vestbo, and S. Rennard Chronic obstructive pulmonary disease biomarker(s) for disease activity needed-urgently Am J Respir Crit Care Med 182 2010 863 864
2. R.E. Walter, J.B. Wilk, M.G. Larson, R.S. Vasan, J.F. Keaney Jr., and I. Lipinska Systemic inflammation and COPD: the Framingham heart study Chest 133 1 2008 19 25
3. G. Engström, N. Segelstorm, M. Ekberg-Aronsson, P.M. Nilsson, F. Lindgärde, and C.G. Löfdahl Plasma markers of inflammation and incidence of hospitalisations for COPD: results from a population-based cohort study Thorax 64 3 2009 211 215
4. W.Q. Gan, S.F. Man, A. Senthilselvan, and D.D. Sin Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis Thorax 59 7 2004 574 580 (Pubitemid 38901515)
5. Y. Higashimoto, T. Iwata, M. Okada, H. Satoh, K. Fukuda, and Y. Tohda Serum biomarkers as predictors of lung function decline in chronic obstructive pulmonary disease Respir Med 103 8 2009 1231 1238
6. F. Garcia-Rio, M. Miravitlles, J.B. Soriano, L. Muñoz, E. Duran-Tauleria, and G. Sánchez Systemic inflammation in chronic obstructive pulmonary disease: a population-based study Respir Res 11 2010 63
7. S.B. Shaker, K.A. von Wachenfeldt, S. Larsson, I. Mile, S. Persdotter, and M. Dahlbäck Identification of patients with chronic obstructive pulmonary disease (COPD) by measurement of plasma biomarkers Clin Respir J 2 1 2008 17 25
8. J.S. Lakind, S.T. Holgate, D.R. Ownby, A.H. Mansur, P.J. Helms, and D. Pyatt A critical review of the use of Clara cell secretory protein (CC16) as a biomarker of acute or chronic pulmonary effects Biomarkers 12 5 2007 445 467 (Pubitemid 47304652)
9. D.A. Lomas, E.K. Silverman, L.D. Edwards, N.W. Locantore, B.E. Miller, and D.H. Horstman Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD Eur Respir J 34 1 2009 95 102
10. C. Lindberg, G. Engström, M. Gerhardsson de Verdier, U. Nihlén, M. Anderson, and K. Forsman-Semb Total desmosines in plasma and urine correlate with lung function Eur Respir J 39 4 2012 839 845
11. W. Ito, M. Takeda, S. Ueki, T. Tanigai, H. Kayaba, and J. Chihara Effect of the hepatocyte growth factor on allergic inflammatory cells Int Arch Allergy Immunol 152 Suppl. 1 2010 96 100
12. R.A. Panganiban, and R.M. Day Hepatocyte growth factor in lung repair and pulmonary fibrosis Acta Pharmacol Sin 32 1 2011 12 20
13. M. Cesari, M. Pahor, and R.A. Incalzi Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions Cardiovasc Ther 28 5 2010 e72 e91
14. Y. Jiang, W. Xiao, Y. Zhang, and Y. Xing Urokinase-type plasminogen activator system and human cationic antimicrobial protein 18 in serum and induced sputum of patients with chronic obstructive pulmonary disease Respirology 15 6 2010 939 946
15. P. Lichtenstein, P.F. Sullivan, S. Cnattingius, M. Gatz, S. Johansson, and E. Carlström The Swedish twin registry in the third millennium: an update Twin Res Hum Genet 9 2006 875 882 (Pubitemid 46093773)
16. J. Hallberg, A. Iliadou, M. Anderson, M.G. de Verdier, U. Nihlén, and M. Dahlbäck Genetic and environmental influence on lung function impairment in Swedish twins Respir Res 11 2010 92
17. J. Vestbo, L.D. Edwards, P.D. Scanlon, J.C. Yates, A. Agusti, and P. Bakke Changes in forced expiratory volume in 1 second over time in COPD N Engl J Med 365 2011 1184 1192
18. V. Pinto-Plata, J. Toso, K. Lee, D. Park, J. Bilello, and H. Mullerova Profiling serum biomarkers in patients with COPD: associations with clinical parameters Thorax 62 7 2007 595 601 (Pubitemid 47056886)
19. J. Sunyer, R. Pistelli, E. Plana, M. Andreani, F. Baldari, and M. Kolz Systemic inflammation, genetic susceptibility and lung function Eur Respir J 32 1 2008 92 97
20. C.E. Bolton, W. Schumacher, J.R. Cockcroft, N.J. Timpson, G.D. Smith, and J. Gallacher The CRP genotype, serum levels and lung function in men: the Caerphilly prospective study Clin Sci (Lond) 120 8 2011 347 355
21. Y.M. van Durme, K.M. Verhamme, A.J. Aarnoudse, G.R. Van Pottelberge, A. Hofman, and J.C. Witteman C-reactive protein levels, haplotypes, and the risk of incident chronic obstructive pulmonary disease Am J Respir Crit Care Med 179 2009 375 382
22. I. Ito, S. Nagai, T. Handa, S. Muro, T. Hirai, and M. Tsukino Matrix metalloproteinase-9 promoter polymorphism associated with upper lung dominant emphysema Am J Respir Crit Care Med 172 2005 1378 1382 (Pubitemid 43069810)
23. H. Schirmer, L. Basso da Silva, P.J. Teixeira, J.S. Moreira, A.L. Moreira, and D. Simon Matrix metalloproteinase gene polymorphisms: lack of association with chronic obstructive pulmonary disease in a Brazilian population Genet Mol Res 8 3 2009 1028 1034
24. J.T. Huang, R. Chaudhuri, O. Albarbarawi, A. Barton, C. Grierson, and P. Rauchhaus Clinical validity of plasma and urinary desmosine as biomarkers for chronic obstructive pulmonary disease Thorax 67 6 2012 502 508
25. S. Ma, Y.Y. Lin, and G.M. Turino Measurements of desmosine and isodesmosine by mass spectrometry in COPD Chest 131 2007 1363 1371 (Pubitemid 46762340)
26. X. Xu, H. Wang, Z. Wang, and W. Xiao Plasminogen activator inhibitor-1 promotes inflammatory process induced by cigarette smoke extraction or lipopolysaccharides in alveolar epithelial cells Exp Lung Res 35 2009 795 805
27. G. Engström, B. Hedblad, P. Nilsson, P. Wollmer, G. Berglund, and L. Janzon Lung function, insulin resistance and incidence of cardiovascular disease: a longitudinal cohort study J Intern Med 253 5 2003 574 581 (Pubitemid 36543297)
28. M.C. Alessi, and I. Juhan-Vague PAI-1 and the metabolic syndrome: links, causes, and consequences Arterioscler Thromb Vasc Biol 26 10 2006 2200 2207 (Pubitemid 44465712)
29. L. Retterstol, L. Eikvar, and K. Berg A twin study of C-reactive protein compared to other risk factors for coronary heart disease Atherosclerosis 169 2003 279 282 (Pubitemid 37297474)
30. Global strategy for diagnosis, management, and prevention of COPD 2011 Available at: www.goldcopd.org