Discriminative ability of LDL-cholesterol to identify patients with familial hypercholesterolemia: A cross-sectional study in 26 406 individuals tested for genetic FH

Circulation: Cardiovascular Genetics

Volumn 5, Issue 3, 2012, Pages 354-359

  Huijgen, Roeland ^a   Hutten, Barbara A ^a   Kindt, Iris ^b   Vissers, Maud N ^a   Kastelein, John J P ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b Foundation for the Identification of Persons with Inherited Hypercholesterolemia   (Netherlands)

Author keywords

Cascade testing; Familial hypercholesterolemia; Genotyping; LDL C; LDL receptor

Indexed keywords

LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; ARTICLE; CHOLESTEROL BLOOD LEVEL; DISEASE SEVERITY; FAMILIAL HYPERCHOLESTEROLEMIA; FAMILY STUDY; FEMALE; GENE MUTATION; GENETIC EPIDEMIOLOGY; GENETIC SCREENING; HETEROZYGOTE; HUMAN; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NETHERLANDS; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

ADULT; AREA UNDER CURVE; CHOLESTEROL, LDL; COHORT STUDIES; CROSS-SECTIONAL STUDIES; DISCRIMINANT ANALYSIS; FEMALE; GENOTYPE; HUMANS; HYPERLIPOPROTEINEMIA TYPE II; MALE; MIDDLE AGED; MUTATION; PREVALENCE; RECEPTORS, LDL; ROC CURVE;

EID: 84864579096     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.111.962456     Document Type: Article

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