Homocysteine is not so paradoxical

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 28, Issue 10, 2008, Pages

  Klevay, Leslie M ^a  

^a UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; HOMOCYSTEINE; VITAMIN B COMPLEX;

ANIMAL; BLOOD; CARDIOVASCULAR DISEASE; DIET SUPPLEMENTATION; HUMAN; HYPERHOMOCYSTEINEMIA; NOTE;

ANIMALS; CARDIOVASCULAR DISEASES; COPPER; DIETARY SUPPLEMENTS; HOMOCYSTEINE; HUMANS; HYPERHOMOCYSTEINEMIA; VITAMIN B COMPLEX;

EID: 84864565533     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.108.172072     Document Type: Letter

References (16)

1. Rodionov RN, Lentz SR. The homocysteine paradox. Arterioscler Thromb Vasc Biol. 2008;28:1031-1033.
2. Jakubowski H. Calcium-dependent human serum homocysteine thiolactone hydrolase. A protective mechanism against protein N-homocysteinylation. J Biol Chem. 2000;275:3957-3962. (Pubitemid 30094622)
3. Liu G, Nellaiappan K, Kagan HM. Irreversible inhibition of lysyl oxidase by homocysteine thiolactone and its selenium and oxygen analogues. Implications for homocystinuria. J Biol Chem. 1997;272:32370-32377. (Pubitemid 28011919)
4. O'Dell BL. Copper. In: Brown ML, ed. Present knowledge in nutrition. Washington, D.C.: International Life Sciences Institute-Nutrition Foundation, 1990:261-267.
5. Tamura T, Turnlund JR. Effect of long-term, high-copper intake on the concentrations of plasma homocysteine and B vitamins in young men. Nutrition. 2004;20:757-759. (Pubitemid 39120032)
6. Klevay LM. Lack of a recommended dietary allowance for copper may be hazardous to your health. J Am Coll Nutr. 1998;17:322-326.
7. Pang Y, MacIntosh DL, Ryan PB. A longitudinal investigation of aggregate oral intake of copper. J Nutr. 2001;131:2171-2176. (Pubitemid 32720648)
8. Anon. Copper. Section 7, In: Dietary reference intakes for vitamin A. vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. Washington, D.C.: National Academy of Sciences, 2001:1-27.
9. Klevay LM. How dietary deficiency, genes and a toxin can cooperate to produce arteriosclerosis and ischemic heart disease. Cell Mol Biol (Noisy-le-grand). 2006;52:11-15. (Pubitemid 46683310)
10. Klevay LM. Trace element and mineral nutrition in disease: Ischemic heart disease. In: Bogden JD, Klevay LM, eds. Clinical Nutrition of the Essential Trace Elements and Minerals: The Guide for Health Professionals. Totowa, NJ: Humana Press Inc., 2000:251-271.
11. Klevay LM. Advances in cardiovascular-copper research. In: First International Bio-Minerals Symposium: Trace Elements in Nutrition, Health and Disease, Schrauzer, GN, ed., Montreal, Canada, Institut Rosell, 2002:64-71.
12. Klevay LM. Endothelial dysfunction, isoprostanes and copper deficiency. Hypertension. In press.
13. Witte KLA, Nikitin NP, Parker AC, von Haehling S, Volk H-D, Anker SD, Clark AL, Cleland JGF. The effect of micronutrient supplementation on quality-of-life and left ventricular function in elderly patients with chronic heart failure. Eur Heart J. 2005;26:2238-2244. (Pubitemid 41541386)
14. Klevay LM. Heart failure improvement from a supplement containing copper. Eur Heart J. 2006;27:117.
15. Clemons TE, Kurinij N, Sperduto RD. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13. Arch Ophthalmol. 2004;122:716-726. (Pubitemid 38607400)
16. Klevay LM. Ischemic heart disease as deficiency disease. Cell Mol Biol (Noisy-le-grand). 2004;50:877-884.