Biotin IgM antibodies in human blood: A previously unknown factor eliciting false results in biotinylation-based immunoassays

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Chen, Tingting ^a   Hedman, Lea ^a   Mattila, Petri S ^b   Jartti, Laura ^c   Jartti, Tuomas ^d   Ruuskanen, Olli ^d   Söderlund Venermo, Maria ^a   Hedman, Klaus ^a,b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c TURKU CITY HOSPITAL   (Finland)

^d TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

AVIDIN; BIOTIN; IMMUNOGLOBULIN M ANTIBODY; STREPTAVIDIN;

ADULT; AGE; AGED; ANTIBODY BLOOD LEVEL; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOTINYLATION; BOCAVIRUS; CHILD; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME IMMUNOASSAY; FALSE POSITIVE RESULT; HUMAN; HUMAN PARVOVIRUS B19; POLYOMA VIRUS; PRESCHOOL CHILD; QUANTITATIVE ANALYSIS; SCHOOL CHILD; SEROPREVALENCE; TRICHODYSPLASIA SPINULOSA POLYOMAVIRUS;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODY AFFINITY; ANTIGENS; BINDING, COMPETITIVE; BIOTIN; BIOTINYLATION; BLOTTING, WESTERN; CHILD; FALSE POSITIVE REACTIONS; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOGLOBULIN M; INHIBITORY CONCENTRATION 50; PROTEIN BINDING; SEROEPIDEMIOLOGIC STUDIES; STREPTAVIDIN;

ARMORACIA RUSTICANA;

EID: 84864563154     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042376     Document Type: Article

References (39)

1. Zempleni J, Mock DM, (1999) Biotin biochemistry and human requirements. J Nutr Biochem 10 (3): 128-138.
2. McMahon R, (2002) Biotin in metabolism and molecular biology. Annu Rev Nutr 22: 221-239.
3. Balnave D, (1977) Clinical symptoms of biotin deficiency in animals. Am J Clin Nutr 30 (9): 1408-1413.
4. Shils ME, Shike M, Ovid Technologies I (2006) Modern nutrition in health and disease. Philadelphia: Lippincott Williams & Wilkins. 2069 p.
5. Wolf B, (2010) Clinical issues and frequent questions about biotinidase deficiency. Mol Genet Metab 100 (1): 6-13: 10.1016/j.ymgme.2010.01.003.
6. Sydenstricker VP, Singal SA, Briggs AP, Devaughn NM, Isbell H, (1942) Preliminary observations on "egg white injury" in man and its cure with a biotin concentrate. Science95 (2459): 176-177: 10.1126/science.95.2459.176.
7. Peters JM, (1967) A separation of the direct toxic effects of dietary raw egg white powder from its action in producing biotin deficiency. Br J Nutr 21 (4): 801-809.
8. Peters JM, Boyd EM, (1969) Toxic effects from a rancid diet containing large amounts of raw egg-white powder. Food Cosmet Toxicol 7 (3): 197-207.
9. Grier RE, Heard GS, Watkins P, Wolf B, (1990) Low biotinidase activities in the sera of patients with impaired liver function: Evidence that the liver is the source of serum biotinidase. Clin Chim Acta 186 (3): 397-400.
10. Hofmann K, Wood SW, Brinton CC, Montibeller JA, Finn FM, (1980) Iminobiotin affinity columns and their application to retrieval of streptavidin. Proc Natl Acad Sci U S A 77 (8): 4666-4668.
11. Sutton A, Vann WF, Karpas AB, Stein KE, Schneerson R, (1985) An avidin-biotin based ELISA for quantitation of antibody to bacterial polysaccharides. J Immunol Methods 82 (2): 215-224.
12. Diamandis EP, Christopoulos TK, (1991) The biotin-(strept)avidin system: Principles and applications in biotechnology. Clin Chem 37 (5): 625-636.
13. Pengo P, Veggiani G, Rattanamanee K, Gallotta A, Beneduce L, et al. (2010) Solid-phase preparation of protein complexes. J Mol Recognit 23 (6): 551-558: 10.1002/jmr.1095.
14. Bratthauer GL, (2010) The avidin-biotin complex (ABC) method and other avidin-biotin binding methods. Methods Mol Biol. 588: 257-270. 10.1007/978-1-59745-324-0_26.
15. Kaikkonen L, Lankinen H, Harjunpaa I, Hokynar K, Söderlund-Venermo M, et al. (1999) Acute-phase-specific heptapeptide epitope for diagnosis of parvovirus B19 infection. J Clin Microbiol 37 (12): 3952-3956.
16. Söderlund-Venermo M, Lahtinen A, Jartti T, Hedman L, Kemppainen K, et al. (2009) Clinical assessment and improved diagnosis of bocavirus-induced wheezing in children, Finland. Emerg Infect Dis 15 (9): 1423-1430.
17. Hedman L, Söderlund-Venermo M, Jartti T, Ruuskanen O, Hedman K, (2010) Dating of human bocavirus infection with protein-denaturing IgG-avidity assays-secondary immune activations are ubiquitous in immunocompetent adults. J Clin Virol 48 (1): 44-48: 10.1016/j.jcv.2010.02.003.
18. Lahtinen A, Kivela P, Hedman L, Kumar A, Kantele A, et al. (2011) Serodiagnosis of primary infections with human parvovirus 4, Finland. Emerg Infect Dis 17 (1): 79-82: 10.3201/eid/1701.100750.
19. Muratsugu M, Yazawa A, Fujiwara S, Nishida S, Fukui T, (2008) Quantitation of biotin-binding immunoglobulins G, A, and M in human sera using F(ab')2anti-human immunoglobulin-coated microplates. Biol Pharm Bull 31 (3): 507-510.
20. Muratsugu M, Muramoto E, Fukui T, (2003) Quantitative measurement of biotin-binding immunoglobulin G in human sera using F(ab')2 anti-human IgG-coated multi-well plates. Biol Pharm Bull 26 (11): 1605-1608.
21. Carvalho JF, Blank M, Kiss E, Tarr T, Amital H, et al. (2007) Anti-vitamin D, vitamin D in SLE: Preliminary results. Ann N Y Acad Sci 1109: 550-557: 10.1196/annals.1398.061.
22. Ailus K, Melamies L, Tuomi T, Palosuo T, Aho K, (1991) Measuring rheumatoid factor in nonrheumatoid subjects: Immunoturbidimetric assay, latex slide test, and enzyme-linked immunosorbent assay compared. Clin Chem 37 (10 Pt 1): 1766-1769.
23. Korpilähde T, Heliövaara M, Kaipiainen-Seppänen O, Knekt P, Aho K, (2003) Regional differences in finland in the prevalence of rheumatoid factor in the presence and absence of arthritis. Ann Rheum Dis 62 (4): 353-355.
24. Shim CN, Hwang JW, Lee J, Koh EM, Cha HS, et al. (2012) Prevalence of rheumatoid factor and parameters associated with rheumatoid factor positivity in korean health screening subjects and subjects with hepatitis B surface antigen. Mod Rheumatol. 10.1007/s10165-012-0603-3.
25. Mock DM, Lankford GL, Mock NI, (1995) Biotin accounts for only half of the total avidin-binding substances in human serum. J Nutr 125 (4): 941-946.
26. Mock DM, (1999) Biotin status: Which are valid indicators and how do we know? J Nutr 129 (2S Suppl): 498S-503S.
27. Bobrovnik SA, (2003) Determination of antibody affinity by ELISA. theory. J Biochem Biophys Methods 57 (3): 213-236.
28. Notkins AL, (2004) Polyreactivity of antibody molecules. Trends Immunol 25 (4): 174-179: 10.1016/j.it.2004.02.004.
29. Burastero SE, Casali P, Wilder RL, Notkins AL, (1988) Monoreactive high affinity and polyreactive low affinity rheumatoid factors are produced by CD5+ B cells from patients with rheumatoid arthritis. J Exp Med 168 (6): 1979-1992.
30. Ternynck T, Avrameas S, (1986) Murine natural monoclonal autoantibodies: A study of their polyspecificities and their affinities. Immunol Rev 94: 99-112.
31. Casali P, Notkins AL, (1989) Probing the human B-cell repertoire with EBV: Polyreactive antibodies and CD5+ B lymphocytes. Annu Rev Immunol 7: 513-535. 10.1146/annurev.iy.07.040189.002501.
32. Nakamura M, Burastero SE, Ueki Y, Larrick JW, Notkins AL, et al. (1988) Probing the normal and autoimmune B cell repertoire with epstein-barr virus. frequency of B cells producing monoreactive high affinity autoantibodies in patients with hashimoto's disease and systemic lupus erythematosus. J Immunol 141 (12): 4165-4172.
33. Ehrenstein MR, Notley CA, (2010) The importance of natural IgM: Scavenger, protector and regulator. Nat Rev Immunol 10 (11): 778-786: 10.1038/nri2849.
34. Dakshinamurti K, Chauhan J, (1990) Nonavidin biotin-binding proteins. Methods Enzymol 184: 93-102.
35. Chatterjee NS, Kumar CK, Ortiz A, Rubin SA, Said HM, (1999) Molecular mechanism of the intestinal biotin transport process. Am J Physiol 277 (4 Pt1): C605-13.
36. Chen T, Hedman L, Mattila PS, Jartti T, Ruuskanen O, et al. (2011) Serological evidence of merkel cell polyomavirus primary infections in childhood. J Clin Virol 50 (2): 125-129: 10.1016/j.jcv.2010.10.015.
37. Chen T, Mattila PS, Jartti T, Ruuskanen O, Söderlund-Venermo M, et al. (2011) Seroepidemiology of the newly found trichodysplasia spinulosa-associated polyomavirus. J Infect Dis. 10.1093/infdis/jir614.
38. Friguet B, Chaffotte AF, Djavadi-Ohaniance L, Goldberg ME, (1985) Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay. J Immunol Methods 77 (2): 305-319.
39. Devey ME, Bleasdale-Barr KM, McLachlan SM, Bradbury J, Clark F, et al. (1989) Serial studies on the affinity and heterogeneity of human autoantibodies to thyroglobulin. Clin Exp Immunol 77 (2): 191-195.