The uncertainty of rituximab and steroid dosing in refractory steroid-resistant nephrotic syndrome

Clinical Nephrology

Volumn 77, Issue 6, 2012, Pages 510-512

  Hirano, Daishi ^a,b   Fujinaga, Shuichiro ^a   Nishizaki, Naoto ^a,c  

^a SAITAMA CHILDREN'S MEDICAL CENTER   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; METHYLPREDNISOLONE; PREDNISOLONE; RITUXIMAB; STEROID; IMMUNOSUPPRESSIVE AGENT; MONOCLONAL ANTIBODY;

ABDOMINAL DISTENSION; CASE REPORT; CHILD; CONGENITAL NEPHROTIC SYNDROME; DRUG MEGADOSE; EDEMA; HUMAN; HYPOVOLEMIA; KIDNEY BIOPSY; LETTER; OLIGURIA; PHYSICAL EXAMINATION; PRESCHOOL CHILD; PROTEINURIA; REFRACTORY PERIOD; REMISSION; URINALYSIS; DRUG ADMINISTRATION; DRUG COMBINATION; DRUG RESISTANCE; FEMALE; MULTIMODALITY CANCER THERAPY; NEPHROTIC SYNDROME; PLASMAPHERESIS; TIME; TREATMENT OUTCOME;

ANTIBODIES, MONOCLONAL, MURINE-DERIVED; CHILD, PRESCHOOL; COMBINED MODALITY THERAPY; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; NEPHROTIC SYNDROME; PLASMA EXCHANGE; REMISSION INDUCTION; STEROIDS; TIME FACTORS; TREATMENT OUTCOME;

EID: 84864562645     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: 10.5414/CN107336     Document Type: Letter

References (12)

1. Ehrich JHH, Geerlings C, Zivicnjak M, Franke D, Geerlings H, Gellermann J. Steroid-resistant idiopathic childhood nephrosis: overdiagnosed and undertreated. Nephrol Dial Transplant. 2007; 22: 2183-2193.
2. Prytuła A, Iijima K, Kamei K, Geary D, Gottlich E, Majeed A, Taylor M, Marks SD, Tuchman S, Camilla R, Ognjanovic M, Filler G, Smith G, Tullus K. Rituximab in refractory nephrotic syndrome. Pediatr Nephrol. 2010; 25: 461-468.
3. Bagga A, Sinha A, Moudgil AN. Rituximab in patients with the steroid-resistant nephrotic syndrome. N Engl J Med. 2007; 356: 2751-2752.
4. Suri M, Tran K, Sharma AP, Filler G, Grimmer J. Remission of steroid-resistant nephrotic syndrome due to focal and segmental glomerulosclerosis using rituximab. Int Urol Nephrol. 2008; 40: 807-810.
5. Kaito H, Kamei K, Kikuchi E, Ogura M, Matsuoka K, Nagata M, Iijima K, Ito S. Successful treatment of collapsing focal segmental glomerulosclerosis with a combination of rituximab, steroids and ciclosporin. Pediatr Nephrol. 2010; 25: 957-959.
6. Nakayama M, Kamei K, Nozu K, Matsuoka K, Nakagawa A, Sako M, Iijima K. Rituximab for refractory focal segmental glomerulosclerosis. Pediatr Nephrol. 2008; 23: 481-485.
7. Fujinaga S, Hirano D, Nishizaki N, Kamei K, Ito S, Ohtomo Y, Shimizu T, Kaneko K. Single infusion of rituximab for persistent steroid-dependent minimal-change nephrotic syndrome after long-term cyclosporine. Pediatr Nephrol. 2010; 25: 539-544.
8. Gulati A, Sinha A, Jordan SC, Hari P, Dinda AK, Sharma S, Srivastava RN, Moudgil A, Bagga A. Efficacy and safety of treatment with rituximab for difficult steroid-resistant and -dependent nephrotic syndrome: multicentric report. Clin J Am Soc Nephrol. 2010; 5: 2207-2212.
9. Kari JA, El-Morshedy SM, El-Desoky S, Alshaya HO, Rahim KA, Edrees BM. Rituximab for refractory cases of childhood nephrotic syndrome. Pediatr Nephrol. 2011; 26: 733-737.
10. Cravedi P, Ruggenenti P, Sghirlanzoni MC, Remuzzi G. Titrating rituximab to circulating B cells to optimize lymphocytolytic therapy in idiopathic membranous nephropathy. Clin J Am Soc Nephrol. 2007; 2: 932-937.
11. Guigonis V, Dallocchio A, Baudouin V, Dehennault M, Hachon-Le Camus C, Afanetti M, Groothoff J, Llanas B, Niaudet P, Nivet H, Raynaud N, Taque S, Ronco P, Bouissou F. Rituximab treatment for severe steroid- or cyclosporine-dependent nephrotic syndrome: a multicentric series of 22 cases. Pediatr Nephrol. 2008; 23: 1269-1279.
12. Fernandez-Fresnedo G, Segarra A, González E, Alexandru S, Delgado R, Ramos N, Egido J, Praga M Trabajo de Enfermedades Glomerulares de la Sociedad Española de Nefrología (GLOSEN). Rituximab treatment of adult patients with steroid-resistant focal segmental glomerulosclerosis. Clin J Am Soc Nephrol. 2009; 4: 1317-1323.