Isocitrate dehydrogenase 1R132H mutation in microglia/macrophages in gliomas: Indication of a significant role of microglia/macrophages in glial tumorigenesis

Cancer Biology and Therapy

Volumn 13, Issue 10, 2012, Pages 836-839

  Zheng, Ping Pin ^a   Van Der Weiden, Marcel ^a   Van Der Spek, Peter J ^a   Vincent, Arnaud J P E ^a   Kros, Johan M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Cell motility; Glioma; IDH1 mutation; Macrophages; Microglia

Indexed keywords

CD68 ANTIGEN; CHEMOKINE RECEPTOR CX3CR1; GLIAL FIBRILLARY ACIDIC PROTEIN; ISOCITRATE DEHYDROGENASE 1;

ARTERIOVENOUS MALFORMATION; ARTICLE; ASTROCYTE; CANCER PROGNOSIS; CARCINOGENESIS; CELL FUNCTION; CELL LINEAGE; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CONTROLLED STUDY; DNA DETERMINATION; DNA SEQUENCE; GENE MUTATION; GLIOMA; HUMAN; HUMAN CELL; MACROPHAGE; MAJOR CLINICAL STUDY; MICROGLIA; MITOSIS; PHAGOCYTOSIS; PROTEIN EXPRESSION; TUMOR GROWTH;

CELL TRANSFORMATION, NEOPLASTIC; COHORT STUDIES; GLIOMA; HUMANS; ISOCITRATE DEHYDROGENASE; MACROPHAGES; MICROGLIA; MUTATION; PROGNOSIS;

EID: 84864546784     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.20836     Document Type: Article

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