Human aldosterone synthase: Recombinant expression in E. coli and purification enables a detailed biochemical analysis of the protein on the molecular level

Journal of Steroid Biochemistry and Molecular Biology

Volumn 132, Issue 1-2, 2012, Pages 57-65

  Hobler, Anna ^a   Kagawa, Norio ^a,c   Hutter, Michael C ^a   Hartmann, Michaela F ^b   Wudy, Stefan A ^b   Hannemann, Frank ^a   Bernhardt, Rita ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Aldosterone; CYP11B2; Hypertension; Steroidogenesis

Indexed keywords

ALDOSTERONE SYNTHASE; CORTICOSTERONE; DEOXYCORTICOSTERONE; HYDROGEN; KETOCONAZOLE; STEROID 11BETA MONOOXYGENASE;

ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ESCHERICHIA COLI; IN VITRO STUDY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; STEROID HYDROXYLATION;

ALDOSTERONE SYNTHASE; CORTICOSTERONE; ENZYME INHIBITORS; ESCHERICHIA COLI; HUMANS; KETOCONAZOLE; MODELS, MOLECULAR; RECOMBINANT PROTEINS;

EID: 84864458519     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2012.03.002     Document Type: Article

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