Targeting TGFβ superfamily ligand accessory proteins as novel therapeutics for chronic lung disorders

Pharmacology and Therapeutics

Volumn 135, Issue 3, 2012, Pages 279-291

  Budd, David C ^a   Holmes, Alan M ^b  

^a HOFFMANN LA ROCHE INC   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Ligand accessory proteins; Lung; Signaling; Transforming growth factor

Indexed keywords

BELAGENPUMATUCEL L; CAT 193; CONNECTIVE TISSUE GROWTH FACTOR; DISITERTIDE; ENDOTHELIN; FG 3019; FRESOLIMUMAB; FS 344; GREMLIN PROTEIN; IMATINIB; LY 2157299; LY 2382770; METELIMUMAB; MONOCLONAL ANTIBODY; P 114; PF 03446962; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN; RN 1001; ROMOSOZUMAB; SB 525334; TRABEDERSEN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3; TRC 105; UNCLASSIFIED DRUG;

ARTICLE; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; HEART MUSCLE FIBROSIS; HUMAN; IDIOPATHIC DISEASE; IN VITRO STUDY; IN VIVO STUDY; LIVER FIBROSIS; LUNG FIBROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PULMONARY HYPERTENSION; SIGNAL TRANSDUCTION;

EID: 84864456941     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2012.06.001     Document Type: Review

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