Cell of origin determines tumor phenotype in an oncogenic ras/p53 knockout transgenic model of high-grade glioma

Journal of Neuropathology and Experimental Neurology

Volumn 71, Issue 8, 2012, Pages 729-740

  Ghazi, Sabah O ^a   Stark, Michelle ^a   Zhao, Zhiguo ^a   Mobley, Bret C ^a   Munden, Alex ^a   Hover, Laura ^a   Abel, Ty William ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

GFAP Cre; Glioma; High grade glioma; Kras; Neural stem progenitor cells; p53; Transgenic mice

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; HERMES ANTIGEN; K RAS PROTEIN; NESTIN; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; PROTEIN P53; TRANSCRIPTION FACTOR SOX2; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL DIFFERENTIATION; GLIOMA; HISTOPATHOLOGY; IN VITRO STUDY; KNOCKOUT MOUSE; MOUSE; NEURAL STEM CELL; NONHUMAN; OLIGODENDROGLIA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUBVENTRICULAR ZONE; TRANSGENIC MOUSE;

ANIMALS; ASTROCYTES; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL LINEAGE; FLUORESCENT ANTIBODY TECHNIQUE; GENES, P53; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOMA; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NEOPLASM TRANSPLANTATION; RAS PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; RECOMBINATION, GENETIC; SURVIVAL ANALYSIS;

EID: 84864453267     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/NEN.0b013e3182625c02     Document Type: Article

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