Effect of bypassing the proximal gut on gut hormones involved with glycemic control and weight loss

Surgery for Obesity and Related Diseases

Volumn 8, Issue 4, 2012, Pages 371-374

  Pournaras, Dimitri J ^a,b   Aasheim, Erlend T ^a   Bueter, Marco ^a   Ahmed, Ahmed R ^a   Welbourn, Richard ^b   Olbers, Torsten ^a   Le Roux, Carel W ^a  

^a CHARING CROSS HOSPITAL   (United Kingdom)

^b MUSGROVE PARK HOSPITAL   (United Kingdom)

Author keywords

Bariatric surgery; Diabetes remission; Gastric bypass; GLP 1; Glucagon like peptide 1; Gut hormones; Incretins; Metabolic surgery

Indexed keywords

GASTROINTESTINAL HORMONE; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; INSULIN; PEPTIDE YY;

ARTICLE; CLINICAL ARTICLE; GASTROSTOMY; GLUCAGON BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLYCEMIC CONTROL; HUMAN; HUMAN TISSUE; INSULIN BLOOD LEVEL; PRIORITY JOURNAL; STOMACH BYPASS; WEIGHT REDUCTION;

ADMINISTRATION, ORAL; ANALYSIS OF VARIANCE; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; ENTERAL NUTRITION; GASTRIC BYPASS; GASTROSTOMY; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE; HOMEOSTASIS; HUMANS; INSULIN; INTESTINE, SMALL; PEPTIDE YY; REMISSION INDUCTION; WEIGHT LOSS;

EID: 84864414363     PISSN: 15507289     EISSN: 18787533     Source Type: Journal    
DOI: 10.1016/j.soard.2012.01.021     Document Type: Article

References (20)

1. J.B. Buse, S. Caprio, W.T. Cefalu How do we define cure of diabetes? Diabetes Care 32 2009 2133 2135
2. F. Rubino, L.M. Kaplan, P.R. Schauer, D.E. Cummings Diabetes Surgery Summit Delegates The Diabetes Surgery Summit Consensus Conference: recommendations for the evaluation and use of gastrointestinal surgery to treat type 2 diabetes mellitus Ann Surg 251 2010 399 405
3. D.J. Pournaras, A. Osborne, S.C. Hawkins Remission of type 2 diabetes after gastric bypass and banding: mechanisms and 2 year outcomes Ann Surg 252 2010 966 971
4. F. Rubino, A. Forgione, D.E. Cummings The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes Ann Surg 244 2006 741 749 (Pubitemid 44629948)
5. M. Tarnoff, L. Rodriguez, A. Escalona Open label, prospective, randomized controlled trial of an endoscopic duodenal-jejunal bypass sleeve versus low calorie diet for pre-operative weight loss in bariatric surgery Surg Endosc 23 2009 650 656
6. R. Schouten, C.S. Rijs, N.D. Bouvy A multicenter, randomized efficacy study of the endobarrier gastrointestinal liner for presurgical weight loss prior to bariatric surgery Ann Surg 251 2010 236 243
7. S.M. Wyles, A.R. Ahmed Tips and tricks in bariatric surgical procedures: a review article Minerva Chir 64 2009 253 264
8. R.L. Batterham, M.A. Cohen, S.M. Ellis Inhibition of food intake in obese subjects by peptide YY3-36 N Engl J Med 349 2003 941 948 (Pubitemid 37064767)
9. A.P. Savage, T.E. Adrian, G. Carolan, V.K. Chatterjee, S.R. Bloom Effects of peptide YY (PYY) on mouth to caecum intestinal transit time and on the rate of gastric emptying in healthy volunteers Gut 28 1987 166 170 (Pubitemid 17027386)
10. B. Kreymann, G. Williams, M.A. Ghatei, S.R. Bloom Glucagon-like peptide-1 7-36: a physiological incretin in man Lancet 2 1987 1300 1304 (Pubitemid 17156636)
11. S.R. Bloom, R.G. Long Radioimmunoassay of gut regulatory peptides 1982 WB Saunders London
12. D.E. Cummings Endocrine mechanisms mediating remission of diabetes after gastric bypass surgery Int J Obes (Lond) 33 Suppl 1 2009 S33 S40
13. D.J. Pournaras, C.W. le Roux Obesity, gut hormones, and bariatric surgery World J Surg 33 2009 1983 1988
14. J. Korner, W. Inabnet, G. Febres Prospective study of gut hormone and metabolic changes after adjustable gastric banding and Roux-en-Y gastric bypass Int J Obes (Lond) 33 2009 786 795
15. B. Laferrère, S. Heshka, K. Wang Incretin levels and effect are markedly enhanced 1 month after Roux-en-Y gastric bypass surgery in obese patients with type 2 diabetes Diabetes Care 30 2007 1709 1716 (Pubitemid 47036341)
16. J. Korner, M. Bessler, W. Inabnet, C. Taveras, J.J. Holst Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding Surg Obes Relat Dis 3 2007 597 601 (Pubitemid 350091417)
17. C.W. le Roux, R. Welbourn, M. Werling Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass Ann Surg 246 2007 780 785 (Pubitemid 350035654)
18. D.J. Pournaras, A. Osborne, S.C. Hawkins The gut hormone response following Roux-en-Y gastric bypass: cross-sectional and prospective study Obes Surg 20 2010 56 60
19. F. Rubino, J. Marescaux Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease Ann Surg 239 2004 1 11 (Pubitemid 38176365)
20. C. Dirksen, D.L. Hansen, S. Madsbad Postprandial diabetic glucose tolerance is normalized by gastric bypass feeding as opposed to gastric feeding and is associated with exaggerated GLP-1 secretion: a case report Diabetes Care 33 2010 375 377