Phenylpropanoid glycosides from plant cell cultures induce heme oxygenase 1 gene expression in a human keratinocyte cell line by affecting the balance of NRF2 and BACH1 transcription factors

Chemico-Biological Interactions

Volumn 199, Issue 2, 2012, Pages 87-95

  Sgarbossa, Anna ^a   Dal Bosco, Martina ^a   Pressi, Giovanna ^b   Cuzzocrea, Salvatore ^c   Dal Toso, Roberto ^b   Menegazzi, Marta ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b Istituto di Ricerche Biotecnologiche Srl   (Italy)

^c UNIVERSITY OF MESSINA   (Italy)

Author keywords

BACH1; Heme oxygenase 1; NRF2; Oxidative stress; Phenylpropanoid glycosides

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ACTEOSIDE; CAMPNEOSIDE 1; CCAAT ENHANCER BINDING PROTEIN; ECHINACOSIDE; FORSYTHOSIDE B; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEME OXYGENASE 1; PHENYLPROPANOID GLYCOSIDE; PLANT GLYCOSIDE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BACH1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL LINE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; GENE EXPRESSION; GENE INDUCTION; HALF LIFE TIME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; KERATINOCYTE; NUCLEAR LOCALIZATION SIGNAL; OXIDATIVE STRESS; PLANT CELL CULTURE; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SKIN PROTECTION; UPREGULATION; WESTERN BLOTTING;

ANTIOXIDANTS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL LINE; CYTOKINES; CYTOPROTECTION; ECHINACEA; FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS; GLYCOSIDES; HEME OXYGENASE-1; HUMANS; KERATINOCYTES; NF-E2-RELATED FACTOR 2; PHENOLS; PHENYLETHYL ALCOHOL; PLANT EXTRACTS; RNA, MESSENGER; SYRINGA; UP-REGULATION;

ANIMALIA;

EID: 84864411479     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.06.006     Document Type: Article

References (49)

1. M.S. Cooke, M.D. Evans, M. Dizdaroglu, and J. Lunec Oxidative DNA damage: mechanisms, mutation, and disease FASEB J. 17 2003 1195 1214
2. I. Bogdan Allemann, and L. Baumann Antioxidants used in skin care formulations Skin Ther. Lett. 13 2008 5 9
3. T.H. Rushmore, and A.N. Kong Pharmacogenomics, regulation and signalling pathways of phase I and phase II drug metabolizing enzymes Curr. Drug Metab. 3 2002 481 490
4. S. Briganti, and M. Picardo Antioxidant activity, lipid peroxidation and skin diseases. What's new J. Eur. Acad. Dermatol. Venereol. 17 2003 663 669
5. C. Hanselmann, C. Mauch, and S. Werner Haem oxygenase-1: a novel player in cutaneous wound repair and psoriasis? Biochem. J. 353 2001 459 466
6. Y. Shindo, E. Witt, D. Han, W. Epstein, and L. Packer Enzymic and non-enzymic antioxidants in epidermis and dermis of human skin J. Invest. Dermatol. 102 1994 122 124
7. S. Immenschuh, V. Hinke, A. Ohlmann, S. Gifhorn-Katz, N. Katz, K. Jungermann, and T. Kietzmann Transcriptional activation of the haem oxygenase-1 gene by cGMP via a cAMP response element/activator protein-1 element in primary cultures of rat hepatocytes Biochem. J. 334 1998 141 146
8. J. Alam, E. Killeen, P. Gong, R. Naquin, B. Hu, D. Stewart, J.R. Ingelfinger, and K.A. Nath Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2 Am. J. Physiol. 284 2003 F743 F752
9. M. Bauer, and I. Bauer Heme oxygenase-1: redox regulation and role in the hepatic response to oxidative stress Antioxid. Redox Signal. 4 2002 749 758
10. 2+, and phospholipase A2 in endothelial cells Am. J. Physiol. 276 1999 H1493 H1501
11. G. Scapagnini, R. Foresti, V. Calabrese, A.M. Giuffrida Stella, C.J. Green, and R. Motterlini Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers Mol. Pharmacol. 61 2002 554 561
12. M.D. Maines Bile pigments: newcomers to the cell signaling arena Toxicol. Sci. 71 2003 9 10
13. T. Nguyen, C.S. Yang, and C.B. Pickett The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress Free Radic. Biol. Med. 37 2004 433 441
14. T. Satoh, S.I. Okamoto, J. Cui, Y. Watanabe, K. Furuta, and M. Suzuki Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic phase II inducers Proc. Natl. Acad. Sci. USA 103 2006 768 773
15. R. Yu, C. Chen, Y.Y. Mo, V. Hebbar, E.D. Owuor, T.H. Tan, and A.N. Kong Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism J. Biol. Chem. 275 2000 39907 39913
16. D. Martin, A.I. Rojo, M. Salinas, R. Diaz, G. Gallardo, J. Alam, C.M. De Galarreta, and A. Cuadrado Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol J. Biol. Chem. 279 2004 8919 8929
17. J. Pi, Y. Bai, J.M. Reece, J. Williams, D. Liu, M.L. Freeman, W.E. Fahl, D. Shugar, J. Liu, W. Qu, S. Collins, and M.P. Waalkes Molecular mechanism of human Nrf2 activation and degradation: role of sequential phosphorylation by protein kinase CK2 Free Radic. Biol. Med. 42 2007 1797 1806
18. S. Braun, C. Hanselmann, M.G. Gassmann, U. auf dem Keller, C. Born-Berclaz, K. Chan, Y.W. Kan, and S. Werner Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound Mol. Cell. Biol. 22 2002 5492 5505
19. K.J. Hintze, Y. Katoh, K. Igarashi, and E.C. Theil Bach1 repression of ferritin and thioredoxin reductase1 is heme-sensitive in cells and in vitro and coordinates expression with heme oxygenase1, beta-globin, and NADP(H) quinone (oxido)reductase 1 J. Biol. Chem. 282 2007 34365 34371
20. M. Ishikawa, S. Numazawa, and T. Yoshida Redox regulation of the transcriptional repressor Bach1 Free Radic. Biol. Med. 38 2005 1344 1352
21. L.G. Korkina Phenylpropanoids as naturally occurring antioxidants: from plant defence to human health Cell. Mol. Biol. (Noisy-le-grand) 53 2007 15 25
22. J.Y. Lee, E.R. Woo, and K.W. Kang Inhibition of lipopolysaccharide- inducible nitric oxide synthase expression by acteoside through blocking of AP-1 activation J. Ethnopharmacol. 97 2005 561 566
23. S. Pastore, A. Potapovich, V. Kostyuk, V. Mariani, D. Lulli, C. De Luca, and L. Korkina Plant polyphenols effectively protect HaCaT cells from ultraviolet C-triggered necrosis and suppress inflammatory chemokine expression Ann. N.Y. Acad. Sci. USA 1171 2009 305 313
24. C.H. Chen, T.Y. Song, Y.C. Liang, and M.L. Hu Acteoside and 6-O-acetylacteoside downregulate cell adhesion molecules induced by IL-1beta through inhibition of ERK and JNK in human vascular endothelial cells J. Agric. Food Chem. 57 2009 8852 8859
25. R. Bauer Chemistry, pharmacology and clinical applications of Echinacea products G. Mazza, B. Oomah, Herbs, Botanicals, and Teas, Functional Foods and Nutraceuticals Series 2000 Technomic Press Lancaster, UK 45 74
26. E. Speroni, P. Govoni, S. Guizzardi, C. Renzulli, and M.C. Guerra Anti-inflammatory and cicatrizing activity of Echinacea pallida Nutt. root extract J. Ethnopharmacol. 79 2002 265 272
27. R.M. Facino, M. Carini, G. Aldini, L. Saibene, P. Pietta, and P. Mauri Echinacoside and caffeoyl conjugates protect collagen from free radical-induced degradation: a potential use of Echinacea extracts in the prevention of skin photodamage Planta Med. 61 1995 510 514
28. Y. Kimura, H. Okuda, S. Nishibe, and S. Arichi Effects of caffeoylglycosides on arachidonate metabolism in leukocytes Planta Med. 53 1997 148 153
29. Y.H. Liao, P.J. Houghton, and J.R.S. Hoult Novel and known constituents from Buddleja species and their activity against leukocyte eicosanoid generation J. Nat. Prod. 62 1999 1241 1245
30. L.G. Korkina, E. Mikhal'chik, M.V. Suprun, S. Pastore, and R. Dal Toso Molecular mechanisms underlying wound healing and anti-inflammatory properties of naturally occurring biotechnologically produced phenylpropanoid glycosides Cell. Mol. Biol. (Noisy-le-grand) 53 2007 84 91
31. M. Yaar, and B.A. Gilchrest Photoageing: mechanism, prevention and therapy Br. J. Dermatol. 157 2007 874 887
32. M.K. Razdan Introduction to Plant Tissue Culture 2003 Science Publishers Enfield, NH
33. P. Molyneux The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity Songklanakarin J. Sci. Technol. 26 2004 211 219
34. F. Denizot, and R. Lang Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability J. Immunol. Methods 89 1986 271 277
35. L. Osborn, S. Kunkel, and G.L. Nabel Tumor necrosis factor alpha and Interleukin 1 stimulate immunodeficiency virus enhancer by activation of nuclear factor kappa B Proc. Natl. Acad. Sci. USA 86 1989 2336 2340
36. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of proteins utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
37. R. Kim, M. Emi, K. Tanabe, and S. Murakami Role of the unfolded protein response in cell death Apoptosis 11 2006 5 13
38. I. Numata, R. Okuyama, A. Memezawa, Y. Ito, K. Takeda, K. Furuyama, S. Shibahara, and S. Aiba Functional expression of heme oxygenase-1 in human differentiated epidermis and its regulation by cytokines J. Invest. Dermatol. 129 2009 2594 2603
39. R.M. Tyrrell, and V.E. Reeve Potential protection of skin by acute UVA irradiation. From cellular to animal model Prog. Biophys. Mol. Biol. 92 2006 86 91
40. R. Motterlini, R. Foresti, R. Bassi, V. Calabrese, J.E. Clark, and C.J. Green Endothelial heme oxygenase-1 induction by hypoxia: modulation by inducible nitric-oxide synthase and S-nitrosothiols J. Biol. Chem. 275 2000 13613 13620
41. H.Y. Lin, S.H. Juan, S.C. Shen, F.L. Hsu, and Y.C. Chen Inhibition of lipopolysaccharide-induced nitric oxide production by flavonoids in RAW264.7 macrophages involves heme oxygenase-1 Biochem. Pharmacol. 66 2003 1821 1832
42. V. Kostyuk, A. Potapovich, T. Suhan, C. De Luca, G. Pressi, R. Dal Toso, and L. Korkina Plant polyphenols against UV-C-induced cell death Planta Med. 74 2008 509 514
43. F. Bolognani, and N.I. Perrone-Bizzozero RNA-protein interactions and control of mRNA stability in neurons J. Neurosci. Res. 86 2008 481 489
44. J.M. Lee, and J.A. Johnson An important role of Nrf2-ARE pathway in the cellular defense mechanism J. Biochem. Mol. Biol. 37 2004 139 143
45. T. Nguyen, P.J. Sherratt, H.C. Huang, C.S. Yang, and C.B. Pickett Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26S proteasome J. Biol. Chem. 278 2003 4536 4541
46. P. Gong, B. Hu, D. Stewart, M. Ellerbe, Y.G. Figueroa, V. Blank, B.S. Beckman, and J. Alam Cobalt induces heme oxygenase-1 expression by a hypoxia-inducible factor-independent mechanism in Chinese hamster ovary cells: regulation by Nrf2 and MafG transcription factors J. Biol. Chem. 276 2001 27018 27025
47. J. Alam, and J.L. Cook Transcriptional regulation of the heme oxygenase- 1 gene via the stress response element pathway Curr. Pharm. Des. 9 2003 2499 2511
48. S. Okada, A. Muto, E. Ogawa, A. Nakanome, Y. Katoh, S. Ikawa, S. Aiba, K. Igarashi, and R. Okuyama Bach1-dependent and -independent regulation of heme oxygenase-1 in keratinocytes J. Biol. Chem. 285 2010 23581 23589
49. R. Motterlini, R. Foresti, R. Bassi, and C.J. Green Curcumin, an anti-oxidant agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress Free Radic. Biol. Med. 28 2000 1303 1312