Ny genteknologisk diagnostik af familiær gastrointestinal stromal tumor

Ugeskrift for Laeger

Volumn 174, Issue 21, 2012, Pages 1462-1464

  Wadt, Karin ^a   Andersen, Mette Klarskov ^a   Hansen, Thomas V O ^a   Gerdes, Anne Marie ^a  

^a International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; IMATINIB; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE; STEM CELL FACTOR RECEPTOR;

AGED; ARTICLE; CASE REPORT; FAMILY; FATALITY; FEMALE; GASTROINTESTINAL STROMAL TUMOR; GENETIC PREDISPOSITION; GENETICS; HUMAN; INTESTINE TUMOR; MALE; MIDDLE AGED; MISSENSE MUTATION; MUTATION; PIGMENT DISORDER;

AGED; ANTINEOPLASTIC AGENTS; FAMILY; FATAL OUTCOME; FEMALE; GASTROINTESTINAL STROMAL TUMORS; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HUMANS; INTESTINAL NEOPLASMS; MALE; MIDDLE AGED; MUTATION, MISSENSE; PIGMENTATION DISORDERS; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-KIT; PYRIMIDINES;

EID: 84864411247     PISSN: 00415782     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Monges G, Bisot-Locard S, Blay JY et al. The estimated incidence of gastrointestinal stromal tumors in France. Bull Cancer 2010;27;E16-22.
2. Heinrich MC, Corless CL, Demetri GD et al. Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. J Clin Oncol 2003;21;4342-9.
3. Veiga I, Silva M, Vieira J et al. Hereditary gastrointestinal stromal tumors sharing the KIT exon 17 germline mutation p.Asp820Tyr develop through different cytogenetic progression pathways. Genes Chromosomes Cancer 2010;49;91-8.
4. Vilain RE, Dudding T, Braye SG et al. Can a familial gastrointestinal tumour syndrome be allelic with Waardenburg syndrome? Clin Genet 2011;79;554-60.
5. Isozaki K, Terris B, Belghiti J et al. Germline-activating mutation in the kinase domain of KIT gene in familial gastrointestinal stromal tumors. Am J Pathol 2000;157;1581-5.