Soluble biomarkers may differentiate psoriasis from psoriatic arthritis

Journal of Rheumatology

Volumn 39, Issue SUPPL. 89, 2012, Pages 65-66

  Chandran, Vinod ^a,b,c  

^a TORONTO WESTERN HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Biomarkers; Psoriasis; Psoriatic arthritis; Screening; Soluble

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; CARTILAGE OLIGOMERIC MATRIX PROTEIN; COLLAGEN TYPE 2; DICKKOPF 1 PROTEIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HERPESVIRUS ENTRY MEDIATOR LIGAND; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 17; INTERLEUKIN 6; KALLIKREIN 10; KALLIKREIN 11; KALLIKREIN 13; KALLIKREIN 5; KALLIKREIN 6; NEUROPSIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; STRATUM CORNEUM CHYMOTRYPTIC ENZYME; STROMELYSIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; MMP3 PROTEIN, HUMAN; PEPTIDE FRAGMENT; PROCOLLAGEN; PROCOLLAGEN TYPE II CARBOXY TERMINAL PEPTIDE; PROCOLLAGEN TYPE II CARBOXY-TERMINAL PEPTIDE; TNFRSF11B PROTEIN, HUMAN;

CARDIOVASCULAR RISK; COMORBIDITY; CONFERENCE PAPER; DIFFERENTIAL DIAGNOSIS; EARLY DIAGNOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; OUTCOME ASSESSMENT; PREVALENCE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PSORIASIS; PSORIATIC ARTHRITIS; QUALITY OF LIFE; SCREENING TEST; ARTICLE; BLOOD; PREDICTIVE VALUE; PROGNOSIS; RECEIVER OPERATING CHARACTERISTIC;

ARTHRITIS, PSORIATIC; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; DIAGNOSIS, DIFFERENTIAL; HUMANS; MATRIX METALLOPROTEINASE 3; OSTEOPROTEGERIN; PEPTIDE FRAGMENTS; PREDICTIVE VALUE OF TESTS; PROCOLLAGEN; PROGNOSIS; PSORIASIS; ROC CURVE;

EID: 84864403918     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.120247     Document Type: Conference Paper

References (12)

1. Naldi L, Mercuri SR. Epidemiology of comorbidities in psoriasis. Dermatol Ther 2010;23:114-8.
2. Mease PJ. Psoriatic arthritis: update on pathophysiology, assessment and management. Ann Rheum Dis 2011;70 Suppl 1:i77-84.
3. Husted JA, Thavaneswaran A, Chandran V, Eder L, Rosen CF, Cook RJ, et al. Cardiovascular and other comorbidities in patients with psoriatic arthritis: a comparison with patients with psoriasis. Arthritis Care Res 2011;63:1729-35.
4. Gladman DD, Thavaneswaran A, Chandran V, Cook RJ. Do patients with psoriatic arthritis who present early fare better than those presenting later in the disease? Ann Rheum Dis 2011;70:2152-4.
5. Radtke MA, Reich K, Blome C, Rustenbach S, Augustin M. Prevalence and clinical features of psoriatic arthritis and joint complaints in 2009 patients with psoriasis: results of a German national survey. J Eur Acad Dermatol Venereol 2009;23:683-91.
6. Leonardi CL, Powers JL, Matheson RT, Goffe BS, Zitnik R, Wang A, et al Etanercept Psoriasis Study Group. Etanercept as monotherapy in patients with psoriasis. N Engl J Med 2003;349:2014-22. (Pubitemid 37448924)
7. Strober B, Teller C, Yamauchi P, Miller JL, Hooper M, Yang YC, et al. Effects of etanercept on C-reactive protein levels in psoriasis and psoriatic arthritis. Br J Dermatol 2008;159:322-30. (Pubitemid 352009830)
8. Skoumal M, Haberhauer G, Fink A, Steiner A, Klingler A, Varga F, et al. Increased serum levels of cartilage oligomeric matrix protein in patients with psoriasis vulgaris: a marker for unknown peripheral joint involvement? Clin Exp Rheumatol 2008;26:1087-90.
9. Alenius GM, Eriksson C, Rantapää Dahlqvist S. Interleukin-6 and soluble interleukin-2 receptor alpha-markers of inflammation in patients with psoriatic arthritis? Clin Exp Rheumatol 2009; 27:120-3.
10. Dalbeth N, Pool B, Smith T, Callon KE, Lobo M, Taylor WJ, et al. Circulating mediators of bone remodeling in psoriatic arthritis: implications for disordered osteoclastogenesis and bone erosion. Arthritis Res Ther 2010;12:R164.
11. Chandran V, Cook RJ, Edwin J, Shen H, Pellett FJ, Shanmugarajah S, et al. Soluble biomarkers differentiate patients with psoriatic arthritis from those with psoriasis without arthritis. Rheumatology 2010;49:1399-405.
12. Eissa A, Gladman DD, Thavaneswaran A, Pellett F, Diamandis E, Chandran V. Serum kallikreins as biomarkers in psoriatic disease. Arthritis Rheum 2011;63 Suppl:S521.