Serum phosphorus as a predictor of low-grade albuminuria in a general population without evidence of chronic kidney disease

Nephrology Dialysis Transplantation

Volumn 27, Issue 7, 2012, Pages 2799-2806

  Lee, Hajeong ^a   Oh, Se Won ^b   Heo, Nam Ju ^c   Chin, Ho Jun ^b   Na, Ki Young ^b   Kim, Suhnggwon ^a   Chae, Dong Wan ^b  

^a Seoul National University Hospital   (South Korea)

^b Seoul National University Bundang Hospital   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

Author keywords

general population; low grade albuminuria; serum phosphorus concentration

Indexed keywords

PHOSPHORUS;

ADULT; AGE; ALBUMINURIA; ARTICLE; BODY MASS; CHRONIC KIDNEY DISEASE; DIABETES MELLITUS; FEMALE; GENDER; GLOMERULUS FILTRATION RATE; HUMAN; HYPERTENSION; LOW GRADE ALBUMINURIA; MAJOR CLINICAL STUDY; MALE; PHOSPHATE BLOOD LEVEL; POPULATION RESEARCH; PRIORITY JOURNAL; RENAL SYSTEM PARAMETERS; URINARY ALBUMIN TO CREATININE RATIO;

ADULT; AGED; ALBUMINURIA; BIOLOGICAL MARKERS; CROSS-SECTIONAL STUDIES; FEMALE; FOLLOW-UP STUDIES; GLOMERULAR FILTRATION RATE; HUMANS; MALE; MIDDLE AGED; PHOSPHORUS; PROGNOSIS; RENAL INSUFFICIENCY, CHRONIC; RISK FACTORS;

EID: 84864403883     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfr762     Document Type: Article

References (42)

1. Kestenbaum B, Sampson J, Rudser K et al. Serum phosphate levels and mortality risk among people with chronic kidney disease. J Am Soc Nephrol 2005; 16: 520-528.
2. Ishimura E, Taniwaki H, Tabata T et al. Cross-sectional association of serum phosphate with carotid intima-medial thickness in hemodialysis patients. Am J Kidney Dis 2005; 45: 859-865.
3. Block GA, Hulbert Shearon TE, Levin NW et al. Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national study. Am J Kidney Dis 1998; 31: 607-617.
4. Ix JH, De Boer IH, Peralta CA et al. Serum phosphorus concentrations and arterial stiffness among individuals with normal kidney function to moderate kidney disease in MESA. Clin J Am Soc Nephrol 2009; 4: 609-615.
5. Tonelli M, Sacks F, Pfeffer M et al. Relation between serum phosphate level and cardiovascular event rate in people with coronary disease. Circulation 2005; 112: 2627-2633.
6. Dhingra R, Sullivan L, Fox C et al. Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community. Arch Intern Med 2007; 167: 879-885.
7. Onufrak S, Bellasi A, Shaw L et al. Phosphorus levels are associated with subclinical atherosclerosis in the general population. Atherosclerosis 2008; 199: 424-431.
8. Foley RN, Collins AJ, Herzog CA et al. Serum phosphorus levels associate with coronary atherosclerosis in young adults. J Am Soc Nephrol 2009; 20: 397-404.
9. Jono S, McKee MD, Murry CE et al. Phosphate regulation of vascular smooth muscle cell calcification. Circ Res 2000; 87: E10-E17.
10. Watson KE, Abrolat ML, Malone LL et al. Active serum vitamin D levels are inversely correlated with coronary calcification. Circulation 1997; 96: 1755-1760.
11. de Boer IH, Rue TC, Kestenbaum B Serum phosphorus concentrations in the third national health and nutrition examination survey (NHANES III). Am J Kidney Dis 2009; 53: 399-407.
12. Winocour PH, Harland JO, Millar JP et al. Microalbuminuria and associated cardiovascular risk factors in the community. Atherosclerosis 1992; 93: 71-81.
13. Dinneen SF, Gerstein HC The association of microalbuminuria and mortality in non-insulin-dependent diabetes mellitus. A systematic overview of the literature. Arch Intern Med 1997; 157: 1413-1418.
14. Rudberg S, Osterby R, Dahlquist G et al. Predictors of renal morphological changes in the early stage of microalbuminuria in adolescents with IDDM. Diabetes Care 1997; 20: 265-271.
15. Mykknen L, Zaccaro DJ, Wagenknecht LE et al. Microalbuminuria is associated with insulin resistance in nondiabetic subjects: the insulin resistance atherosclerosis study. Diabetes 1998; 47: 793-800.
16. Gerstein HC, Mann JF, Yi Q et al. Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals. JAMA 2001; 286: 421-426.
17. Rachmani R, Levi Z, Lidar M et al. Considerations about the threshold value of microalbuminuria in patients with diabetes mellitus: lessons from an 8-year follow-up study of 599 patients. Diabetes Res Clin Pract 2000; 49: 187-194.
18. Hillege H, Fidler V, Diercks GFH et al. Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population. Circulation 2002; 106: 1777-1782.
19. Klausen K, Borch-Johnsen K, Feldt-Rasmussen B et al. Very low levels of microalbuminuria are associated with increased risk of coronary heart disease and death independently of renal function, hypertension, and diabetes. Circulation 2004; 110: 32-35.
20. Romundstad S, Holmen J, Hallan H et al. Microalbuminuria and allcause mortality in treated hypertensive individuals: does sex matter? The Nord-Trøndelag Health Study (HUNT), Norway. Circulation 2003; 108: 2783-2789.
21. Romundstad S, Holmen J, Kvenild K et al. Microalbuminuria and all-cause mortality in 2,089 apparently healthy individuals: a 4.4-year follow-up study. The Nord-Trøndelag Health Study (HUNT), Norway. Am J Kidney Dis 2003; 42: 466-473.
22. Yuyun M, Khaw KT, Luben R et al. Microalbuminuria, cardiovascular risk factors and cardiovascular morbidity in a British population: the EPIC-Norfolk population-based study. Eur J Cardiovasc Prev Rehabil 2004; 11: 207-213.
23. Ingelsson E, Sundstrm J, Lind L et al. Low-grade albuminuria and the incidence of heart failure in a community-based cohort of elderly men. Eur Heart J 2007; 28: 1739-1745.
24. Arnlv J, Evans J, Meigs J et al. Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart Study. Circulation 2005; 112: 969-975.
25. Verhave JC, Hillege HL, Burgerhof JG et al. Cardiovascular risk factors are differently associated with urinary albumin excretion in men and women. J Am Soc Nephrol 2003; 14: 1330-1335.
26. Stehouwer CDA, Smulders Y Microalbuminuria and risk for cardiovascular disease: analysis of potential mechanisms. J Am Soc Nephrol 2006; 17: 2106-2111.
27. Levey AS, Coresh J, Balk E et al. National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann Intern Med 2003; 139: 137-147.
28. Lee S, Park H, Kim D et al. Appropriate waist circumference cutoff points for central obesity in Korean adults. Diabetes Res Clin Pract 2007; 75: 72-80.
29. Heo N, Ahn J, Lee T et al. Very low-grade albuminuria reflects susceptibility to chronic kidney disease in combination with cardiovascular risk factors. Hypertens Res 2010; 33: 573-578.
30. Shuto E, Taketani Y, Tanaka R et al. Dietary phosphorus acutely impairs endothelial function. J Am Soc Nephrol 2009; 20: 1504-1512.
31. Rodondi N, Yerly P, Gabriel A et al. Microalbuminuria, but not cystatin C, is associated with carotid atherosclerosis in middle-aged adults. Nephrol Dial Transplant 2007; 22: 1107-1114.
32. Jørgensen L, Jenssen T, Johnsen S et al. Albuminuria as risk factor for initiation and progression of carotid atherosclerosis in non-diabetic persons: the Tromsø Study. Eur Heart J 2007; 28: 363-369.
33. Ballermann BJ, Stan RV Resolved: capillary endothelium is a major contributor to the glomerular filtration barrier. J Am Soc Nephrol 2007; 18: 2432-2438.
34. Clausen P, Jensen JS, Jensen G et al. Elevated urinary albumin excretion is associated with impaired arterial dilatory capacity in clinically healthy subjects. Circulation 2001; 103: 1869-1874.
35. Dogra G, Rich L, Stanton K et al. Endothelium-dependent and independent vasodilation studies at normoglycaemia in type I diabetes mellitus with and without microalbuminuria. Diabetologia 2001; 44: 593-601.
36. Ceravolo R, Maio R, Pujia A et al. Pulse pressure and endothelial dysfunction in never-treated hypertensive patients. J Am Coll Cardiol 2003; 41: 1753-1758.
37. He FJ, Markandu ND, Sagnella GA et al. Plasma sodium. Hypertension 2005; 45: 98-102.
38. de Wardener HE, He FJ, MacGregor GA Plasma sodium and hypertension. Kidney Int 2004; 66: 2454-2466.
39. Oberleithner H, Riethmüller C, Schillers H et al. Plasma sodium stiffens vascular endothelium and reduces nitric oxide release. Proc Natl Acad Sci USA 2007; 104: 16281-16286.
40. Sudhir K, Kurtz TW, Yock PG et al. Potassium preserves endothelial function and enhances aortic compliance in Dahl rats. Hypertension 1993; 22: 315-322.
41. Zhou MS, Kosaka H, Yoneyama H Potassium augments vascular relaxation mediated by nitric oxide in the carotid arteries of hypertensive Dahl rats. Am J Hypertens 2000; 13: 666-672.
42. Macdonald JE, Struthers AD What is the optimal serum potassium level in cardiovascular patients?. J Am Coll Cardiol 2004; 43: 155-161.