CARD15 and Toll-like receptor 4 mutations in Italian patients with inflammatory bowel disease

Digestive and Liver Disease

Volumn 44, Issue 9, 2012, Pages 800-801

  Guagnozzi, Danila ^a,c   Pagnini, Cristiano ^b,c   Fave, Gianfranco Delle ^b   Corleto, Vito Domenico ^b,c  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c Research Center S Pietro   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; TOLL LIKE RECEPTOR 4;

ALLELE; CROHN DISEASE; ENTERITIS; GENE INTERACTION; GENE MUTATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; INTESTINE OBSTRUCTION; INTESTINE RESECTION; LETTER; MAJOR CLINICAL STUDY; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; ULCERATIVE COLITIS;

ADOLESCENT; ADULT; ALLELES; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; COLITIS, ULCERATIVE; CONFIDENCE INTERVALS; CROHN DISEASE; GENOTYPE; HUMANS; MIDDLE AGED; NOD2 SIGNALING ADAPTOR PROTEIN; ODDS RATIO; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RETROSPECTIVE STUDIES; TOLL-LIKE RECEPTOR 4; YOUNG ADULT;

EID: 84864402982     PISSN: 15908658     EISSN: 18783562     Source Type: Journal    
DOI: 10.1016/j.dld.2012.03.024     Document Type: Letter

References (5)

1. Braat H., Stokkers P., Hommes T., et al. Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn's disease patients. J Mol Med (Berl) 2005, 83:601-609.
2. Economou M., Trikalinos T.A., Loizou K.T., et al. Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. Am J Gastroenterol 2004, 99:2393-2404.
3. Shen X., Shi R., Zhang H., et al. The Toll-like receptor 4 D299G and T399I polymorphisms are associated with Crohn's disease and ulcerative colitis: a meta-analysis. Digestion 2010, 81:69-77.
4. Giachino D., van Duist M.M., Regazzoni S., et al. Analysis of the CARD15 variants R702W, G908R and L1007fs in Italian IBD patients. Eur J Hum Genet 2004, 12:206-212.
5. Rigoli L., Romano C., Caruso R.A., et al. Clinical significance of NOD2/CARD15 and Toll-like receptor 4 gene single nucleotide polymorphisms in inflammatory bowel disease. World J Gastroenterol 2008, 14:4454-4461.