Update in paroxysmal nocturnal hemoglobinuria

Clinical Advances in Hematology and Oncology

Volumn 10, Issue 6, 2012, Pages 391-393

  Hillmen, Peter ^a  

^a LEEDS TEACHING HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; CD59 ANTIGEN; COMPLEMENT COMPONENT C5; COUMARIN; CYCLOSPORIN; ECULIZUMAB; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; HEMOGLOBIN; LACTATE DEHYDROGENASE; WARFARIN;

ABDOMINAL PAIN; APLASTIC ANEMIA; ARTICLE; BLOOD TRANSFUSION; BONE MARROW DEPRESSION; BONE MARROW TRANSPLANTATION; CYTOPENIA; DYSPHAGIA; ERECTILE DYSFUNCTION; FLOW CYTOMETRY; GENE; GENE MUTATION; HEADACHE; HEMOLYSIS; HUMAN; INTERNATIONAL NORMALIZED RATIO; KIDNEY FAILURE; LETHARGY; NEISSERIACEAE INFECTION; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PIG A GENE; PREGNANCY; PROPHYLAXIS; THROMBOSIS;

ANTIBODIES, MONOCLONAL; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTICOAGULANTS; BONE MARROW TRANSPLANTATION; HEMOGLOBINURIA, PAROXYSMAL; HUMANS; PROGNOSIS; RESEARCH;

EID: 84864392930     PISSN: 15430790     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Kelly RJ, Hill A, Arnold LM, et al. Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: sustained efficacy and improved survival. Blood. 2011;117:6786-6792.
2. Kelly RJ, Hill A, Arnold LM, Khursigara G, Kanagasundaram NS, Hillmen P. Eculizumab for patients with paroxysmal nocturnal hemoglobinuria (PNH) is effective during the maintenance of hemodialysis for end stage renal failure. Leuk Res. 2011;35:560-562.
3. Hill A, Rother RP, Arnold L, et al. Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization. Haematologica. 2010;95:567-573.
4. Hillmen P, Lewis SM, Bessler M, Luzzatto L, Dacie JV. Natural history of paroxys- mal nocturnal hemoglobinuria. N Engl J Med. 1995;333:1253-1258.