Integrated QSAR study for inhibitors of hedgehog signal pathway against multiple cell lines: A collaborative filtering method

BMC Bioinformatics

Volumn 13, Issue 1, 2012, Pages

  Gao, Jun ^a,b   Che, Dongsheng ^c   Zheng, Vincent W ^d,e   Zhu, Ruixin ^a   Liu, Qi ^a  

^a TONGJI UNIVERSITY   (China)

^b SHANGHAI MARITIME UNIVERSITY   (China)

^c EAST STROUDSBURG UNIVERSITY   (United States)

^d Advanced Digital Sciences Center   (United States)

^e NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER THERAPY; CELL LINES; COLLABORATIVE ENVIRONMENTS; COLLABORATIVE FILTERING METHODS; CONTROL-CELL; EFFICIENT FEATURE SELECTIONS; EMBRYONIC DEVELOPMENT; HEDGEHOG SIGNALING; HEDGEHOG SIGNALING PATHWAYS; IMPORTANT FEATURES; MULTIPLE CELLS; MULTIPLE TARGETS; QSAR MODEL; QSAR MODELING; QSAR STUDIES; SIGNAL PATHWAYS; SIGNALING PATHWAYS; SINGLE CELLS; STRUCTURE ACTIVITY RELATIONSHIPS;

CELL CULTURE; CELL GROWTH; CHEMICAL MODIFICATION; GROWTH KINETICS; LEAD COMPOUNDS; MOLECULAR GRAPHICS;

COMPUTATIONAL CHEMISTRY;

ERINACEIDAE;

ANTINEOPLASTIC AGENT; CYCLOPAMINE; G PROTEIN COUPLED RECEPTOR; SMO PROTEIN, HUMAN; SONIC HEDGEHOG PROTEIN; VERATRUM ALKALOID;

ARTICLE; CELL PROLIFERATION; CHEMICAL MODEL; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; HUMAN; METABOLISM; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; HEDGEHOG PROTEINS; HUMANS; MODELS, CHEMICAL; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; VERATRUM ALKALOIDS;

EID: 84864359509     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-13-186     Document Type: Article

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