Is reactivation of autophagy a possible therapeutic solution for obesity and metabolic syndrome?

Autophagy

Volumn 8, Issue 8, 2012, Pages 1252-1254

  Sciarretta, Sebastiano ^a,b   Volpe, Massimo ^b,c   Sadoshima, Junichi ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b IRCCS NEUROMED   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Autophagy; Ischemia; Metabolic syndrome; mTOR; Obesity; Rheb

Indexed keywords

AMINO ACID; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; LIPID; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN P73; REACTIVE OXYGEN METABOLITE; RHEB PROTEIN; SIRTUIN 1; TRANSCRIPTION FACTOR FKHR;

ACUTE CORONARY SYNDROME; ATHEROSCLEROTIC PLAQUE; AUTOPHAGY; CELL DEATH; CELL SURVIVAL; DEACETYLATION; ENDOPLASMIC RETICULUM STRESS; GLUCOSE INTOLERANCE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN SENSITIVITY; LIPID DIET; METABOLIC SYNDROME X; MITOCHONDRION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PROTEIN PHOSPHORYLATION; SHORT SURVEY; SIGNAL TRANSDUCTION;

EID: 84864351256     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.20670     Document Type: Short Survey

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