메뉴 건너뛰기




Volumn 361, Issue 1-2, 2012, Pages 153-164

Synergistic actions of insulin-sensitive and Sirt1-mediated pathways in the differentiation of mouse embryonic stem cells to osteoblast

Author keywords

Adipocytes; Akt; Differentiation; Insulin; Osteoblast; Sirt1

Indexed keywords

ALKALINE PHOSPHATASE; INSULIN; MESSENGER RNA; PROTEIN KINASE B; SIRTUIN 1;

EID: 84864334969     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.04.002     Document Type: Article
Times cited : (17)

References (48)
  • 1
    • 49749094742 scopus 로고    scopus 로고
    • Is teratoma formation in stem cell research a characterization tool or a window to developmental biology?
    • Aleckovic M., Simon C. Is teratoma formation in stem cell research a characterization tool or a window to developmental biology?. Reprod. Biomed. Online 2008, 17:270-280.
    • (2008) Reprod. Biomed. Online , vol.17 , pp. 270-280
    • Aleckovic, M.1    Simon, C.2
  • 2
    • 33745514431 scopus 로고    scopus 로고
    • Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells
    • Backesjo C.M., et al. Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells. J. Bone Miner. Res. 2006, 21:993-1002.
    • (2006) J. Bone Miner. Res. , vol.21 , pp. 993-1002
    • Backesjo, C.M.1
  • 3
    • 0023276009 scopus 로고
    • Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: a comparative histomorphometric study
    • Burkhardt R., et al. Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: a comparative histomorphometric study. Bone 1987, 8:157-164.
    • (1987) Bone , vol.8 , pp. 157-164
    • Burkhardt, R.1
  • 4
    • 77956382385 scopus 로고    scopus 로고
    • Sirtuin1 regulation of developmental genes during differentiation of stem cells
    • Calvanese V., et al. Sirtuin1 regulation of developmental genes during differentiation of stem cells. Proc. Natl. Acad. Sci. USA 2010, 107(31):13736-13741.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , Issue.31 , pp. 13736-13741
    • Calvanese, V.1
  • 5
    • 40849135716 scopus 로고    scopus 로고
    • Apoptotic mechanisms involved in neurodegenerative diseases: experimental and therapeutic approaches
    • Camins A., et al. Apoptotic mechanisms involved in neurodegenerative diseases: experimental and therapeutic approaches. Methods Finds Exp. Clin. Pharmacol. 2008, 30:43-65.
    • (2008) Methods Finds Exp. Clin. Pharmacol. , vol.30 , pp. 43-65
    • Camins, A.1
  • 6
    • 0141814680 scopus 로고    scopus 로고
    • Developmental defects and p53 hyperacetylation is sir2 homolog (Sirt1) deficient mice
    • Cheng H.L., et al. Developmental defects and p53 hyperacetylation is sir2 homolog (Sirt1) deficient mice. Proc. Natl. Acad. Sci. USA 2003, 100(19):10794-10799.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , Issue.19 , pp. 10794-10799
    • Cheng, H.L.1
  • 7
    • 0023277545 scopus 로고
    • Single step method of RNA isolation by acid guanidium thiocyanate- phenol-chloroform extraction
    • Chomczynski P., Sacchi N. Single step method of RNA isolation by acid guanidium thiocyanate- phenol-chloroform extraction. Anal. Biochem. 1987, 162:156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 8
    • 45349084772 scopus 로고    scopus 로고
    • Sirt1 deficiency attenuates spermatogenesis and germ cell function
    • Coussens M., et al. Sirt1 deficiency attenuates spermatogenesis and germ cell function. PloS One 2008, 3:e1571.
    • (2008) PloS One , vol.3
    • Coussens, M.1
  • 10
    • 33748942837 scopus 로고    scopus 로고
    • Transcriptional control of adipocyte formation
    • Farmer S.R. Transcriptional control of adipocyte formation. Cell Metab. 2006, 4:263-273.
    • (2006) Cell Metab. , vol.4 , pp. 263-273
    • Farmer, S.R.1
  • 11
    • 43049121395 scopus 로고    scopus 로고
    • Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt
    • Fulco M., et al. Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Dev. Cell 2008, 14:661-673.
    • (2008) Dev. Cell , vol.14 , pp. 661-673
    • Fulco, M.1
  • 12
    • 77955082747 scopus 로고    scopus 로고
    • Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition
    • Fulzele K., et al. Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition. Cell 2010, 142(2):309-319.
    • (2010) Cell , vol.142 , Issue.2 , pp. 309-319
    • Fulzele, K.1
  • 13
    • 56849088732 scopus 로고    scopus 로고
    • Metformin regulates osteoblast and adipocyte differentiation of rat mesenchymal stem cells
    • Gao Y., et al. Metformin regulates osteoblast and adipocyte differentiation of rat mesenchymal stem cells. J. Pharm. Pharmacol. 2008, 60(12):1695-1700.
    • (2008) J. Pharm. Pharmacol. , vol.60 , Issue.12 , pp. 1695-1700
    • Gao, Y.1
  • 14
    • 0023933166 scopus 로고
    • Role of insulin in growth hormone-stimulated 3T3 cell adipogenesis
    • Guller S., et al. Role of insulin in growth hormone-stimulated 3T3 cell adipogenesis. Endocrinology 1988, 122(5):2084-2089.
    • (1988) Endocrinology , vol.122 , Issue.5 , pp. 2084-2089
    • Guller, S.1
  • 15
    • 0242396694 scopus 로고
    • Embryonic stem cell and hematopoiesis
    • Wiley-Liss, New York, R.I. Freshney, I.B. Pragnell, M.G. Freshney (Eds.)
    • Hole N., Smith A.G. Embryonic stem cell and hematopoiesis. Culture of Hematopoetic Cells 1994, 235-249. Wiley-Liss, New York. R.I. Freshney, I.B. Pragnell, M.G. Freshney (Eds.).
    • (1994) Culture of Hematopoetic Cells , pp. 235-249
    • Hole, N.1    Smith, A.G.2
  • 16
    • 33746419250 scopus 로고    scopus 로고
    • Prospective study of diabetes and risk of hip fracture: the nurses' health study
    • Janghorbani M., et al. Prospective study of diabetes and risk of hip fracture: the nurses' health study. Diabetes Care 2006, 29:1573-1578.
    • (2006) Diabetes Care , vol.29 , pp. 1573-1578
    • Janghorbani, M.1
  • 17
    • 15844427939 scopus 로고    scopus 로고
    • Wortmannin-sensitive trafficking pathways in chinese hamster ovary cells
    • Jayme L., et al. Wortmannin-sensitive trafficking pathways in chinese hamster ovary cells. J. Biol. Chem. 1996, 271(18):10953-10962.
    • (1996) J. Biol. Chem. , vol.271 , Issue.18 , pp. 10953-10962
    • Jayme, L.1
  • 18
    • 0033933211 scopus 로고    scopus 로고
    • Osteopenia in insulin-dependent diabetes mellitus; prevalence and aspects of pathophysiology
    • Kemink S.A., et al. Osteopenia in insulin-dependent diabetes mellitus; prevalence and aspects of pathophysiology. J. Endocrinol. Invest. 2000, 23:295-303.
    • (2000) J. Endocrinol. Invest. , vol.23 , pp. 295-303
    • Kemink, S.A.1
  • 19
    • 0029810614 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling
    • Kenner K.A., et al. Protein tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling. J. Biol. Chem. 1996, 271:19810-19816.
    • (1996) J. Biol. Chem. , vol.271 , pp. 19810-19816
    • Kenner, K.A.1
  • 20
    • 0035958904 scopus 로고    scopus 로고
    • Insulin-induced adipocyte differentiation
    • Klemm D.J., et al. Insulin-induced adipocyte differentiation. J. Biol. Chem. 2001, 276(30):28430-28435.
    • (2001) J. Biol. Chem. , vol.276 , Issue.30 , pp. 28430-28435
    • Klemm, D.J.1
  • 21
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227(5259):680-685.
    • (1970) Nature , vol.227 , Issue.5259 , pp. 680-685
    • Laemmli, U.K.1
  • 22
    • 48349107136 scopus 로고    scopus 로고
    • Roles of Wnt/β- catenin signaling in adipogenic differentiation potential of adipose-derived mesenchymal stem cells
    • Li H.X., et al. Roles of Wnt/β- catenin signaling in adipogenic differentiation potential of adipose-derived mesenchymal stem cells. Mol. Cell. Endocrinol. 2008, 291:116-124.
    • (2008) Mol. Cell. Endocrinol. , vol.291 , pp. 116-124
    • Li, H.X.1
  • 23
    • 0029891232 scopus 로고    scopus 로고
    • Expression of a constitutively activated form of protein kinase B (c- Akt) in 3T3-L1 preadipose cells causes spontaneous differentiation
    • Magun R., et al. Expression of a constitutively activated form of protein kinase B (c- Akt) in 3T3-L1 preadipose cells causes spontaneous differentiation. Endocrinology 1996, 137:3590-3593.
    • (1996) Endocrinology , vol.137 , pp. 3590-3593
    • Magun, R.1
  • 24
    • 0037207475 scopus 로고    scopus 로고
    • The mammalian SIR2 alpha protein has a role in embryogenesis and gametogenesis
    • McBurney, et al. The mammalian SIR2 alpha protein has a role in embryogenesis and gametogenesis. Mol. Cell. Biol. 2003, 23(1):38-54.
    • (2003) Mol. Cell. Biol. , vol.23 , Issue.1 , pp. 38-54
    • McBurney1
  • 25
    • 0028807726 scopus 로고
    • Anabolic effects of insulin on bone suggest a role for chromium picolinate in preservation of bone density
    • McCarty M.F. Anabolic effects of insulin on bone suggest a role for chromium picolinate in preservation of bone density. Med. Hypotheses 1995, 45(3):241-246.
    • (1995) Med. Hypotheses , vol.45 , Issue.3 , pp. 241-246
    • McCarty, M.F.1
  • 26
    • 0015137446 scopus 로고
    • Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies
    • Meunier P., et al. Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies. Clin. Orthop. Relat. Res. 1971, 80:147-154.
    • (1971) Clin. Orthop. Relat. Res. , vol.80 , pp. 147-154
    • Meunier, P.1
  • 27
    • 84855879737 scopus 로고    scopus 로고
    • Geranylgeranylpyrophosphate stimulates PPARγ expression and adipogenesis through the inhibition of osteoblast differentiation
    • Megam M., et al. Geranylgeranylpyrophosphate stimulates PPARγ expression and adipogenesis through the inhibition of osteoblast differentiation. Bone 2011, 10.1016/j.bone.2011.09.056.
    • (2011) Bone
    • Megam, M.1
  • 28
    • 23744432422 scopus 로고    scopus 로고
    • Effect of streptozotocin induced diabetes mellitus on alveolar bone deposition in the rat
    • Mishima N., et al. Effect of streptozotocin induced diabetes mellitus on alveolar bone deposition in the rat. Arch. Oral Biol. 2002, 47:843-849.
    • (2002) Arch. Oral Biol. , vol.47 , pp. 843-849
    • Mishima, N.1
  • 29
    • 0031953736 scopus 로고    scopus 로고
    • Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: implications for osteopenic disorders
    • Nuttall M.E., et al. Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: implications for osteopenic disorders. J. Bone Miner. Res. 1998, 13:371-382.
    • (1998) J. Bone Miner. Res. , vol.13 , pp. 371-382
    • Nuttall, M.E.1
  • 30
    • 0036090574 scopus 로고    scopus 로고
    • Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) α or β
    • Okazaki R., et al. Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) α or β. Endocrinology 2002, 143(6):2349-2356.
    • (2002) Endocrinology , vol.143 , Issue.6 , pp. 2349-2356
    • Okazaki, R.1
  • 31
    • 0032924683 scopus 로고    scopus 로고
    • Interconversion potential of cloned human marrow adipocytes in vitro
    • Park S.R., et al. Interconversion potential of cloned human marrow adipocytes in vitro. Bone 1999, 24:549-554.
    • (1999) Bone , vol.24 , pp. 549-554
    • Park, S.R.1
  • 32
    • 3042681042 scopus 로고    scopus 로고
    • Sirt1 promotes fat mobilization in white adipocytes by repressing PPARγ
    • Picard F., et al. Sirt1 promotes fat mobilization in white adipocytes by repressing PPARγ. Nature 2004, 429:771-776.
    • (2004) Nature , vol.429 , pp. 771-776
    • Picard, F.1
  • 33
    • 42349085704 scopus 로고    scopus 로고
    • Sirt1 contributes critically to the redox-dependent fate of neural progenitors
    • Prozorovski T., et al. Sirt1 contributes critically to the redox-dependent fate of neural progenitors. Nat. Cell Biol. 2008, 10:385-394.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 385-394
    • Prozorovski, T.1
  • 34
    • 0024851161 scopus 로고
    • The characterization, regulation, and function of insulin receptors on osteoblast-like clonal osteosarcoma cell line
    • Pun K.K., et al. The characterization, regulation, and function of insulin receptors on osteoblast-like clonal osteosarcoma cell line. J. Bone Miner. Res. 1989, 4:853-862.
    • (1989) J. Bone Miner. Res. , vol.4 , pp. 853-862
    • Pun, K.K.1
  • 35
    • 40949128686 scopus 로고    scopus 로고
    • Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways
    • Raucci A., et al. Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways. J. Cell Physiol. 2008, 215(2):442-451.
    • (2008) J. Cell Physiol. , vol.215 , Issue.2 , pp. 442-451
    • Raucci, A.1
  • 36
    • 0035479915 scopus 로고    scopus 로고
    • Mouse ES cells: experimental exploitation of pluripotent differentiation potential
    • Rathjen J., Rathjen P.D. Mouse ES cells: experimental exploitation of pluripotent differentiation potential. Curr. Opin. Genet. Dev. 2000, 11:587-594.
    • (2000) Curr. Opin. Genet. Dev. , vol.11 , pp. 587-594
    • Rathjen, J.1    Rathjen, P.D.2
  • 37
    • 0032994523 scopus 로고    scopus 로고
    • Insulin acutely regulates the expression of the peroxisome proliferator-activated receptor in human adipocytes
    • Rieusset J., et al. Insulin acutely regulates the expression of the peroxisome proliferator-activated receptor in human adipocytes. Diabetes 1999, 48:699-705.
    • (1999) Diabetes , vol.48 , pp. 699-705
    • Rieusset, J.1
  • 38
    • 70449701416 scopus 로고    scopus 로고
    • Osteopontin induces β-catenin signaling through activation of Akt in prostate cancer cells
    • Robertson B.W., Chellaiah M.A. Osteopontin induces β-catenin signaling through activation of Akt in prostate cancer cells. Exp. Cell Res. 2010, 316:1-11.
    • (2010) Exp. Cell Res. , vol.316 , pp. 1-11
    • Robertson, B.W.1    Chellaiah, M.A.2
  • 39
    • 11844291416 scopus 로고    scopus 로고
    • Ectopic overexpression of adipogenic transcription factors induces transdifferentiation of MC3T3-E1 osteoblasts
    • Sang W.K., et al. Ectopic overexpression of adipogenic transcription factors induces transdifferentiation of MC3T3-E1 osteoblasts. Biochem. Biophys. Res. Commun. 2005, 327:811-819.
    • (2005) Biochem. Biophys. Res. Commun. , vol.327 , pp. 811-819
    • Sang, W.K.1
  • 40
    • 73149114381 scopus 로고    scopus 로고
    • Early activation of the β-catenin pathway in osteocytes is mediated by nitric oxide, phosphatidylinositol-3kinase/Akt, and focal adhesion kinase
    • Santos A., et al. Early activation of the β-catenin pathway in osteocytes is mediated by nitric oxide, phosphatidylinositol-3kinase/Akt, and focal adhesion kinase. Biochem. Biophys. Res. Commun. 2010, 391:364-369.
    • (2010) Biochem. Biophys. Res. Commun. , vol.391 , pp. 364-369
    • Santos, A.1
  • 41
    • 84864350307 scopus 로고    scopus 로고
    • Potential role of protein deacetylase Sirt1 in methotrexate chemotherapy-induced bone and bone marrow damage
    • Shandala T. Potential role of protein deacetylase Sirt1 in methotrexate chemotherapy-induced bone and bone marrow damage. Bone 2009, 44:S166.
    • (2009) Bone , vol.44
    • Shandala, T.1
  • 42
    • 34548857700 scopus 로고    scopus 로고
    • SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B
    • Sun C., et al. SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. Cell Metab. 2007, 6:307-319.
    • (2007) Cell Metab. , vol.6 , pp. 307-319
    • Sun, C.1
  • 43
    • 0034066670 scopus 로고    scopus 로고
    • Insulin-like growth factor-I in diabetes mellitus: its physiology, metabolic effects, and potential clinical utility
    • Thrailkill K.M. Insulin-like growth factor-I in diabetes mellitus: its physiology, metabolic effects, and potential clinical utility. Diabetes Technol. Ther. 2000, 2:69-80.
    • (2000) Diabetes Technol. Ther. , vol.2 , pp. 69-80
    • Thrailkill, K.M.1
  • 44
    • 34548827057 scopus 로고    scopus 로고
    • Resveratrol inhibits tumor growth of human neuroblastoma and mediates apoptosis by directly targeting mitochondria
    • Van Ginkel P.R., et al. Resveratrol inhibits tumor growth of human neuroblastoma and mediates apoptosis by directly targeting mitochondria. Clin. Cancer Res. 2007, 13:5162-5169.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 5162-5169
    • Van Ginkel, P.R.1
  • 45
    • 70350371629 scopus 로고    scopus 로고
    • Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor γ transactivation
    • Xie Y.B. Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor γ transactivation. J. Biol. Chem. 2009, 284(42):28762-28774.
    • (2009) J. Biol. Chem. , vol.284 , Issue.42 , pp. 28762-28774
    • Xie, Y.B.1
  • 46
    • 77953522380 scopus 로고    scopus 로고
    • Insulin stimulates osteoblast proliferation and differentiation through ERK and PI3K in MG-63 cells
    • Yang J., et al. Insulin stimulates osteoblast proliferation and differentiation through ERK and PI3K in MG-63 cells. Cell Biochem. Funct. 2010, 28:334-341.
    • (2010) Cell Biochem. Funct. , vol.28 , pp. 334-341
    • Yang, J.1
  • 47
    • 36348974168 scopus 로고    scopus 로고
    • The direct involvement of Sirt1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation
    • Zhang J. The direct involvement of Sirt1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation. J. Biol. Chem. 2007, 282(47):34356-34364.
    • (2007) J. Biol. Chem. , vol.282 , Issue.47 , pp. 34356-34364
    • Zhang, J.1
  • 48
    • 70349472930 scopus 로고    scopus 로고
    • Resveratrol augments the canonical Wnt signaling pathway in promoting osteoblastic differentiation of multipotent mesenchymal cells
    • Zhou H., et al. Resveratrol augments the canonical Wnt signaling pathway in promoting osteoblastic differentiation of multipotent mesenchymal cells. Exp. Cell Res. 2009, 315(17):2953-2962.
    • (2009) Exp. Cell Res. , vol.315 , Issue.17 , pp. 2953-2962
    • Zhou, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.