Carnitine deficiency presenting with encephalopathy and hyperammonemia in a patient receiving chronic enteral tube feeding: A case report

Journal of Medical Case Reports

Volumn 6, Issue , 2012, Pages

  Ling, Peter ^a   Lee, Douglas J ^b,c   Yoshida, Eric M ^a,c   Sirrs, Sandra ^a,c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b VANCOUVER COASTAL HEALTH   (Canada)

^c VANCOUVER GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; CARNITINE; PHENYTOIN;

ADULT; AGITATION; ARTICLE; BEHAVIOR CHANGE; BRAIN DISEASE; CARNITINE DEFICIENCY; CASE REPORT; CONFUSION; DELIRIUM; DROWSINESS; HUMAN; HYPERAMMONEMIA; MALE; MENTAL DISEASE; NASOGASTRIC TUBE; PRIORITY JOURNAL; SEIZURE; TOTAL PARENTERAL NUTRITION; TRAFFIC ACCIDENT; TUBE FEEDING; UNSPECIFIED SIDE EFFECT;

EID: 84864334407     PISSN: None     EISSN: 17521947     Source Type: Journal    
DOI: 10.1186/1752-1947-6-227     Document Type: Article

References (10)

1. Carnitine metabolism and inborn errors. Engel AG, Rebouche CJ, J Inherit Metab Dis 1984 7 Suppl 1 38 43 6434843
2. Role of carnitine in human nutrition. Feller AG, Rudman D, J Nutr 1988 118 541 547 3284979
3. Plasma carnitine levels in patients receiving home parenteral nutrition. Bowyer BA, Fleming CR, Ilstrup D, Nelson J, Reek S, Burnes J, Am J Clin Nutr 1986 43 85 91 3079943
4. Hyperammonemic encephalopathy caused by carnitine deficiency. Limketkai BN, Zucker SD, J Gen Intern Med 2008 23 210 213 10.1007/s11606-007-0473-0 18080167
5. HHH syndrome (hyperornithinaemia, hyperammonaemia, homocitrullinuria), with fulminant hepatitis-like presentation. Fecarotta S, Parenti G, Vajro P, Zuppaldi A, Della Casa R, Carbone MT, Correra A, Torre G, Riva S, Dionisi-Vici C, Santorelli FM, Andria G, J Inherit Metab Dis 2006 29 186 189 10.1007/s10545-006-0120-7 16601889
6. Carnitine biosynthesis in mammals. Vaz FM, Wanders RJ, Biochem J 2002 361 417 429 10.1042/0264-6021:3610417 11802770
7. Carnitine deficiency with hyperbilirubinemia, generalized skeletal muscle weakness and reactive hypoglycemia in a patient on long-term total parenteral nutrition: treatment with intravenous L-carnitine. Worthley LI, Fishlock RC, Snoswell AM, JPEN J Parenter Enteral Nutr 1983 7 176 180 10.1177/ 0148607183007002176 6406707
8. Reduction of serum carnitine concentrations during anticonvulsant therapy with phenobarbital, valproic acid, phenytoin, and carbamazepine in children. Hug G, McGraw CA, Bates SR, Landrigan EA, J Pediatr 1991 119 799 802 10.1016/S0022-3476(05)80306-3 1941389
9. Carnitine deficiency in epilepsy: risk factors and treatment. Coulter DL, J Child Neurol 1995 10 Suppl 2 32 S39 8576567
10. Serum carnitine levels in epileptic children before and during treatment with valproic acid, carbamazepine, and phenobarbital. Castro-Gago M, Eirís-Pũal J, Novo-Rodríguez MI, Couceiro J, Camĩa F, Rodríguez-Segade S, J Child Neurol 1998 13 546 549 10.1177/ 088307389801301104 9853647