I148M PNPLA3 variant and progressive liver disease: A new paradigm in hepatology

Hepatology

Volumn 56, Issue 2, 2012, Pages 791-

  Valenti, Luca ^a   Alisi, Anna ^b   Nobili, Valerio ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; INSULIN; PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING PROTEIN 3; PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ALCOHOL LIVER CIRRHOSIS; ALLELE; BODY MASS; DISEASE PREDISPOSITION; DISEASE SEVERITY; ENZYME ACTIVITY; GENETIC MODEL; GENETIC POLYMORPHISM; GENOTYPE; HEPATITIS C; HUMAN; INSULIN RESISTANCE; LETTER; LIPID BLOOD LEVEL; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER FIBROSIS; NONALCOHOLIC FATTY LIVER; PHENOTYPE; PRIORITY JOURNAL;

EID: 84864329234     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.25634     Document Type: Letter

References (4)

1. Sookoian S, Pirola CJ. Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease. HEPATOLOGY 2011; 53: 1883-1894.
2. Valenti L, Alisi A, Galmozzi E, Bartuli A, Del Menico B, Alterio A, et al. I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease. HEPATOLOGY 2010; 52: 1274-1280.
3. Stickel F, Buch S, Lau K, Zu Schwabedissen HM, Berg T, Ridinger M, et al. Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in Caucasians. HEPATOLOGY 2011; 53: 86-95.
4. Valenti L, Rumi M, Galmozzi E, Aghemo A, Del Menico B, De Nicola S, et al. Patatin-Like phospholipase domain-containing 3 I148M polymorphism, steatosis, and liver damage in chronic hepatitis C. HEPATOLOGY 2011; 53: 791-799.