Central role of IL-6 and MMP-1 for cross talk between human intestinal mast cells and human intestinal fibroblasts

Immunobiology

Volumn 217, Issue 9, 2012, Pages 912-919

  Montier, Yves ^a   Lorentz, Axel ^a   Krämer, Sigrid ^a   Sellge, Gernot ^b   Schock, Martin ^c   Bauer, Michael ^d   Schuppan, Detlef ^e,f   Bischoff, Stephan C ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c Katharinenhospital   (Germany)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^e HARVARD MEDICAL SCHOOL   (United States)

^f JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Fibroblasts; Fibrosis; Immune regulation; Inflammation; Intestinal immunity; Mast cells

Indexed keywords

HISTAMINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; INTERSTITIAL COLLAGENASE; NEUTRALIZING ANTIBODY; TRYPTASE; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL COUNT; CELL FUNCTION; CELL INTERACTION; CELL STIMULATION; CELL SURVIVAL; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; INTESTINE CELL; MAST CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL TIME; UPREGULATION;

APOPTOSIS; CELL COMMUNICATION; CELL SURVIVAL; COCULTURE TECHNIQUES; FIBROBLASTS; FLAVONOIDS; HUMANS; INTERLEUKIN-6; INTESTINES; MAST CELLS; MATRIX METALLOPROTEINASE 1; PROTEIN KINASE INHIBITORS; RECEPTOR CROSS-TALK;

EID: 84864306528     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2012.01.003     Document Type: Article

References (36)

1. Agarwal S., Baran C., Piesco N.P., Quintero J.C., Langkamp H.H., Johns L.P., Chandra C.S. Synthesis of proinflammatory cytokines by human gingival fibroblasts in response to lipopolysaccharides and interleukin-1 beta. J. Periodontal. Res. 1995, 30:382-389.
2. Alessi D.R., Cuenda A., Cohen P., Dudley D.T., Saltiel A.R. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo. J. Biol. Chem. 1995, 270:27489-27494.
3. Artuc M., Steckelings U.M., Henz B.M. Mast cell-fibroblast interactions: human mast cells as source and inducers of fibroblast and epithelial growth factors. J. Invest. Dermatol. 2002, 118:391-395.
4. Bischoff S.C. Role of mast cells in allergic and non-allergic immune responses: comparison of human and murine data. Nat. Rev. Immunol. 2007, 7:93-104.
5. Bischoff S.C., Sellge G., Lorentz A., Sebald W., Raab R., Manns M.P. IL-4 enhances proliferation and mediator release in mature human mast cells. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:8080-8085.
6. Brew K., Nagase H. The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity. Biochim. Biophys. Acta 2010, 1803:55-71.
7. Cruse G., Cockerill S., Bradding P. IgE alone promotes human lung mast cell survival through the autocrine production of IL-6. BMC Immunol. 2008, 9:2.
8. Fitzgerald S.M., Lee S.A., Hall H.K., Chi D.S., Krishnaswamy G. Human lung fibroblasts express interleukin-6 in response to signaling after mast cell contact. Am. J. Respir. Cell. Mol. Biol. 2004, 30:585-593.
9. Galli S.J., Grimbaldeston M., Tsai M. Immunomodulatory mast cells: negative, as well as positive, regulators of immunity. Nat. Rev. Immunol. 2008, 8:478-486.
10. Garbuzenko E., Nagler A., Pickholtz D., Gillery P., Reich R., Maquart F.X., Levi-Schaffer F. Human mast cells stimulate fibroblast proliferation, collagen synthesis and lattice contraction: a direct role for mast cells in skin fibrosis. Clin. Exp. Allergy 2002, 32:237-246.
11. Garbuzenko E., Berkman N., Puxeddu I., Kramer M., Nagler A., Levi-Schaffer F. Mast cells induce activation of human lung fibroblasts in vitro. Exp. Lung Res. 2004, 30:705-721.
12. Gebhardt T., Sellge G., Lorentz A., Raab R., Manns M.P., Bischoff S.C. Cultured human intestinal mast cells express functional IL-3 receptors and respond to IL-3 by enhancing growth and IgE receptor-dependent mediator release. Eur. J. Immunol. 2002, 32:2308-2316.
13. Günther U., Schuppan D., Bauer M., Matthes H., Stallmach A., Schmitt-Gräff A., Riecken E.O., Herbst H. Fibrogenesis and fibrolysis in collagenous colitis. Patterns of procollagen types I and IV, matrix-metalloproteinase-1 and -13, and TIMP-1 gene expression. Am. J. Pathol. 1999, 155:493-503.
14. Hollins F., Kaur D., Yang W., Cruse G., Saunders R., Sutcliffe A., Berger P., Ito A., Brightling C.E., Bradding P. Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J. Immunol. 2008, 181:2772-2780.
15. Hu Z.Q., Kobayashi K., Zenda N., Shimamura T. Tumor necrosis factor-alpha- and interleukin-6-triggered mast cell development from mouse spleen cells. Blood 1997, 89:526-533.
16. Kambe M., Kambe N., Oskeritzian C.A., Schechter N., Schwartz L.B. IL-6 attenuates apoptosis, while neither IL-6 nor IL-10 affect the numbers or protease phenotype of fetal liver-derived human mast cells. Clin. Exp. Allergy 2001, 31:1077-1085.
17. Kanbe N., Kurosawa M., Nagata H., Yamashita T., Kurimoto F., Miyachi Y. Production of fibrogenic cytokines by cord blood-derived cultured human mast cells. J. Allergy Clin. Immunol. 2000, 106:85-90.
18. Laulederkind S.J., Bielawska A., Raghow R., Hannun Y.A., Ballou L.R. Ceramide induces interleukin 6 gene expression in human fibroblasts. J. Exp. Med. 1995, 182:599-604.
19. Levi-Schaffer F., Austen K.F., Caulfield J.P., Hein A., Gravallese P.M., Stevens R.L. Co-culture of human lung-derived mast cells with mouse 3T3 fibroblasts: morphology and IgE-mediated release of histamine, prostaglandin D2, and leukotrienes. J. Immunol. 1987, 139:494-500.
20. Levi-Schaffer F., Kelav-Appelbaum R., Rubinchik E. Human foreskin mast cell viability and functional activity is maintained ex vivo by coculture with fibroblasts. Cell. Immunol. 1995, 162:211-216.
21. Lorentz A., Schwengberg S., Sellge G., Manns M.P., Bischoff S.C. Human intestinal mast cells are capable of producing different cytokine profiles: role of IgE receptor cross-linking and IL-4. J. Immunol. 2000, 164:43-48.
22. Lorentz A., Klopp I., Gebhardt T., Manns M.P., Bischoff S.C. Role of activator protein 1, nuclear factor-kappaB, and nuclear factor of activated T cells in IgE receptor-mediated cytokine expression in mature human mast cells. J. Allergy Clin. Immunol. 2003, 111:1062-1068.
23. Lorentz A., Wilke M., Sellge G., Worthmann H., Klempnauer J., Manns M.P., Bischoff S.C. IL-4-induced priming of human intestinal mast cells for enhanced survival and Th2 cytokine generation is reversible and associated with increased activity of ERK1/2 and c-Fos. J. Immunol. 2005, 174:6751-6756.
24. Mierke C.T., Ballmaier M., Werner U., Manns M.P., Welte K., Bischoff S.C. Human endothelial cells regulate survival and proliferation of human mast cells. J. Exp. Med. 2000, 192:801-811.
25. Page-McCaw A., Ewald A.J., Werb Z. Matrix metalloproteinases and the regulation of tissue remodelling. Nat. Rev. Mol. Cell. Biol. 2007, 8:221-233.
26. Pardo A., Selman M. MMP-1: the elder of the family. Int. J. Biochem. Cell. Biol. 2005, 37:283-288.
27. Rieder F., Fiocchi C. Intestinal fibrosis in IBD-a dynamic, multifactorial process. Nat. Rev. Gastroenterol. Hepatol. 2009, 6:228-235.
28. Sellge G., Bischoff S.C. Isolation, culture, and characterization of intestinal mast cells. Methods Mol. Biol. 2006, 315:123-138.
29. Sellge G., Lorentz A., Gebhardt T., Levi-Schaffer F., Bektas H., Manns M.P., Schuppan D., Bischoff S.C. Human intestinal fibroblasts prevent apoptosis in human intestinal mast cells by a mechanism independent of stem cell factor, IL-3 IL-4, and nerve growth factor. J. Immunol. 2004, 172:260-267.
30. Shimizu Y., Suga T., Maeno T., Aoki F., Tsukagoshi H., Kawata T., Sakai K., Narita T., Takahashi T., Ishikawa S., Morishita Y., Nakajima T., Hara F., Miura T., Kurabayashi M. Functional expression of high-affinity receptor for immunoglobulin E on mast cells precedes that of tryptase during differentiation from human bone marrow-derived CD34 progenitors cultured in the presence of stem cell factor and interleukin-6. Clin. Exp. Allergy 2004, 34:917-925.
31. Shiohara M., Koike K. Regulation of mast cell development. Chem. Immunol. Allergy 2005, 87:1-21.
32. Sugihara A., Tsujimura T., Fujita Y., Nakata Y., Terada N. Evaluation of role of mast cells in the development of liver fibrosis using mast cell-deficient rats and mice. J. Hepatol. 1999, 30:859-867.
33. Tasaki K., Shintani Y., Saotome T., Andoh A., Fujiyama Y., Hozawa S., Bamba T. Pro-inflammatory cytokine-induced matrix metalloproteinase-1 (MMP-1) secretion in human pancreatic periacinar myofibroblasts. Pancreatology 2003, 3:414-421.
34. Tiggelman A.M., Boers W., Linthorst C., Brand H.S., Sala M., Chamuleau R.A. Interleukin-6 production by human liver (myo)fibroblasts in culture. Evidence for a regulatory role of LPS, IL-1 beta and TNF alpha. J. Hepatol. 1995, 23:295-306.
35. Yanagida M., Fukamachi H., Ohgami K., Kuwaki T., Ishii H., Uzumaki H., Amano K., Tokiwa T., Mitsui H., Saito H., Iikura Y., Ishizaka T., Nakahata T. Effects of T-helper 2-type cytokines, interleukin-3 (IL-3) IL-4, IL-5, and IL-6 on the survival of cultured human mast cells. Blood 1995, 86:3705-3714.
36. Zhang Y., Lehman J.M., Petti L.M. Apoptosis of mortal human fibroblasts transformed by the bovine papillomavirus E5 oncoprotein. Mol. Cancer Res. 2002, 1:122-136.