Endoluminal gingival fibroblast transfer reduces the size of rabbit carotid aneurisms via elastin repair

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 32, Issue 8, 2012, Pages 1892-1901

  Durand, Eric ^a,b   Fournier, Benjamin ^a,b   Couty, Ludovic ^a,b   Lemitre, Mathilde ^a,b   Achouh, Paul ^a,b   Julia, Pierre ^a,b   Trinquart, Ludovic ^a,c   Fabiani, Jean Noel ^a,b   Seguier, Sylvie ^a   Gogly, Bruno ^a,b   Coulomb, Bernard ^a,b   Lafont, Antoine ^a,b  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^c ACTION Study Group   (France)

Author keywords

aneurism; cell therapy; elastin; fibroblasts; metalloproteinase

Indexed keywords

ELASTIN; GELATINASE B; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY WALL; ARTICLE; BLOOD VESSEL DIAMETER; CAROTID ARTERY ANEURYSM; CELL TRANSPLANTATION; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; EXPERIMENTAL RABBIT; EXTRACELLULAR MATRIX; FIBROBLAST; GINGIVA; NONHUMAN; PRIORITY JOURNAL;

ANEURYSM; ANIMALS; CAROTID ARTERY DISEASES; CELL SURVIVAL; CELLS, CULTURED; ELASTIN; FIBROBLASTS; GINGIVA; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; RABBITS; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 84864288093     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.251439     Document Type: Article

References (23)

1. Sakalihasan N, Limet R, Defawe OD. Abdominal aortic aneurysm. Lancet. 2005;365:1577-1589. (Pubitemid 40615407)
2. Shah PK. Inflammation, metalloproteinases, and increased proteolysis: an emerging pathophysiological paradigm in aortic aneurysm. Circulation. 1997;96:2115-2117. (Pubitemid 27425809)
3. López-Candales A, Holmes DR, Liao S, Scott MJ, Wickline SA, Thompson RW. Decreased vascular smooth muscle cell density in medial degeneration of human abdominal aortic aneurysms. Am J Pathol. 1997;150:993-1007. (Pubitemid 27106171)
4. Longo GM, Xiong W, Greiner TC, Zhao Y, Fiotti N, Baxter BT. Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. J Clin Invest. 2002;110:625-632. (Pubitemid 34988786)
5. Freestone T, Turner RJ, Coady A, Higman DJ, Greenhalgh RM, Powell JT. Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol. 1995;15:1145-1151.
6. Luttun A, Lutgens E, Manderveld A, Maris K, Collen D, Carmeliet P, Moons L. Loss of matrix metalloproteinase-9 or matrix metalloproteinase-12 protects apolipoprotein E-deficient mice against atherosclerotic media destruction but differentially affects plaque growth. Circulation. 2004;109:1408-1414. (Pubitemid 38387828)
7. Allaire E, Forough R, Clowes M, Starcher B, Clowes AW. Local overexpression of TIMP-1 prevents aortic aneurysm degeneration and rupture in a rat model. J Clin Invest. 1998;102:1413-1420. (Pubitemid 28467570)
8. Qian HS, Gu JM, Liu P, Kauser K, Halks-Miller M, Vergona R, Sullivan ME, Dole WP, Deng GG. Overexpression of PAI-1 prevents the development of abdominal aortic aneurysm in mice. Gene Ther. 2008;15:224-232. (Pubitemid 351150045)
9. Dai J, Losy F, Guinault AM, Pages C, Anegon I, Desgranges P, Becquemin JP, Allaire E. Overexpression of transforming growth factor-beta1 stabilizes already-formed aortic aneurysms: a first approach to induction of functional healing by endovascular gene therapy. Circulation. 2005;112:1008-1015. (Pubitemid 41170269)
10. Pyo R, Lee JK, Shipley JM, Curci JA, Mao D, Ziporin SJ, Ennis TL, Shapiro SD, Senior RM, Thompson RW. Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms. J Clin Invest. 2000;105:1641-1649. (Pubitemid 30390315)
11. Allaire E, Muscatelli-Groux B, Guinault AM, Pages C, Goussard A, Mandet C, Bruneval P, Méllière D, Becquemin JP. Vascular smooth muscle cell endovascular therapy stabilizes already developed aneurysms in a model of aortic injury elicited by inflammation and proteolysis. Ann Surg. 2004;239:417-427. (Pubitemid 38229073)
12. Schor SL, Ellis I, Irwin CR, Banyard J, Seneviratne K, Dolman C, Gilbert AD, Chisholm DM. Subpopulations of fetal-like gingival fibroblasts: characterisation and potential significance for wound healing and the progression of periodontal disease. Oral Dis. 1996;2:155-166. (Pubitemid 26310906)
13. Häkkinen L, Uitto VJ, Larjava H. Cell biology of gingival wound healing. Periodontol 2000. 2000;24:127-152.
14. Gogly B, Naveau A, Fournier B, Reinald N, Durand E, Brasselet C, Coulomb B, Lafont A. Preservation of rabbit aorta elastin from degradation by gingival fibroblasts in an ex vivo model. Arterioscler Thromb Vasc Biol. 2007;27:1984-1990. (Pubitemid 47312308)
15. Reinald N, Fournier B, Naveau A, Couty L, Lemitre M, Seguier S, Coulomb B, Gogly B, Lafont A, Durand E. Fusiform aneurysm model in rabbit carotid artery. J Vasc Res. 2010;47:61-68.
16. Lafont A, Durand E, Samuel JL, Besse B, Addad F, Lévy BI, Desnos M, Guérot C, Boulanger CM. Endothelial dysfunction and collagen accumulation: two independent factors for restenosis and constrictive remodeling after experimental angioplasty. Circulation. 1999;100:1109-1115. (Pubitemid 29416238)
17. Naveau A, Reinald N, Fournier B, Durand E, Lafont A, Coulomb B, Gogly B. Gingival fibroblasts inhibit MMP-1 and MMP-3 activities in an ex-vivo artery model. Connect Tissue Res. 2007;48:300-308. (Pubitemid 350285394)
18. Bartold PM, Narayanan AS. Molecular and cell biology of healthy and diseased periodontal tissues. Periodontol 2000. 2006;40:29-49. (Pubitemid 43434240)
19. Tsuruga E, Irie K, Sakakura Y, Yajima T. Expression of fibrillins and tropoelastin by human gingival and periodontal ligament fibroblasts in vitro. J Periodont Res. 2002;37:23-28.
20. Sauvage M, Hinglais N, Mandet C, Badier C, Deslandes F, Michel JB, Jacob MP. Localization of elastin mRNA and TGF-beta1 in rat aorta and caudal artery as a function of age. Cell Tissue Res. 1998;291:305-314. (Pubitemid 28081854)
21. Dimmeler S, Burchfield J, Zeiher AM. Cell-based therapy of myocardial infarction. Arterioscler Thromb Vasc Biol. 2008;28:208-216. (Pubitemid 351161191)
22. Zeng L, Hu Q, Wang X, Mansoor A, Lee J, Feygin J, Zhang G, Suntharalingam P, Boozer S, Mhashilkar A, Panetta CJ, Swingen C, Deans R, From AH, Bache RJ, Verfaillie CM, Zhang J. Bioenergetic and functional consequences of bone marrow-derived multipotent progenitor cell transplantation in hearts with postinfarction left ventricular remodeling. Circulation. 2007;115:1866-1875. (Pubitemid 46598900)
23. Menasche P. Cardiac cell therapy: lessons from clinical trials. J Mol Cell Cardiol. 2011;50:258-265.