Activity of IQG-607, a new orally active compound, in a murine model of Mycobacterium tuberculosis infection

International Journal of Antimicrobial Agents

Volumn 40, Issue 2, 2012, Pages 182-185

  Rodrigues Junior, Valnês S ^a   Dos Santos Junior, André ^a   Dos Santos, Anderson Jader ^a   Schneider, Cristopher Zandoná ^a   Calixto, João B ^b   Sousa, Eduardo Henrique Silva ^c   De França Lopes, Luiz Gonzaga ^c   Souto, André Arigony ^a   Basso, Luiz Augusto ^a   Santos, Diógenes Santiago ^a   Campos, Maria M ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^c FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

Drug development; InhA inhibitor; IQG 607; Mycobacterium tuberculosis; Pre clinical test; Tuberculosis

Indexed keywords

IQG 607; IQG 639; ISONIAZID; PENTACYANO(ISONIAZID)FERRATE; PENTACYANO[2 METIL 5 (PIRIDIN 4 IL) 1,3,4 OXADIAZOLE]FERRATE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; DOSE RESPONSE; LUNG; MALE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SPLEEN; SPLENOMEGALY; TUBERCULOSIS;

ANIMALS; ANTITUBERCULAR AGENTS; BACTERIAL LOAD; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; FERROUS COMPOUNDS; ISONIAZID; LUNG; LUNG DISEASES; MALE; MICE; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; OXADIAZOLES; TUBERCULOSIS;

EID: 84864284596     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2012.04.019     Document Type: Article

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