A genome-wide association study identifies KNG1 as a genetic determinant of plasma factor XI level and activated partial thromboplastin time

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 32, Issue 8, 2012, Pages 2008-2016

  Sabater Lleal, Maria ^a   Martinez Perez, Angel ^b   Buil, Alfonso ^b,c   Folkersen, Lasse ^a   Souto, Juan Carlos ^d   Bruzelius, Maria ^a   Borrell, Montserrat ^d   Odeberg, Jacob ^a   Silveira, Angela ^a   Eriksson, Per ^a   Almasy, Laura ^e   Hamsten, Anders ^a   Soria, José Manuel ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b BIOMEDICAL RESEARCH INSTITUTE SANT PAU IIB SANT PAU   (Spain)

^c UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^d HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^e SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

activated partial thromboplastin time; factor XI; genome wide associations; kininogen; thrombosis

Indexed keywords

BLOOD CLOTTING FACTOR 11; KININOGEN; MESSENGER RNA;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION; GENE LOCUS; GENE MAPPING; GENETIC ANALYSIS; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; KININOGEN 1 GENE; MALE; NORMAL HUMAN; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURAL GENE; THROMBOSIS;

ADULT; AGED; AGED, 80 AND OVER; CHROMOSOME MAPPING; FACTOR XI; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; KININOGENS; MALE; MIDDLE AGED; PARTIAL THROMBOPLASTIN TIME; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84864282214     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.248492     Document Type: Article

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