Endothelial cells require related transcription enhancer factor-1 for cell-cell connections through the induction of gap junction proteins

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 32, Issue 8, 2012, Pages 1951-1959

  An, Xiaojin ^a   Jin, Yi ^a   Philbrick, Melissa J ^b   Wu, Jiaping ^b   Messmer Blust, Angela ^b   Song, Xiaoxiao ^b   Cully, Brittany L ^b   He, Ping ^b   Xu, Ming ^b   Duffy, Heather S ^b   Li, Jian ^a  

^a PEKING UNIVERSITY   (China)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

cell cell connections; connexin 43; endothelial cells; gap junctions; related transcription enhancer factor 1

Indexed keywords

BETA CATENIN; CLAUDIN 5; CONNEXIN 37; CONNEXIN 40; CONNEXIN 43; GAP JUNCTION PROTEIN; MATRIGEL; NERVE CELL ADHESION MOLECULE; OCCLUDIN; OXYGEN; PROTEIN ZO1; PROTEIN ZO2; RELATED TRANSCRIPTION ENHANCER FACTOR 1; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY; CELL AGGREGATION; CELL COMMUNICATION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; RETINA BLOOD VESSEL; RETINOPATHY; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ANIMALS; CELL AGGREGATION; CELL COMMUNICATION; CELLS, CULTURED; CONNEXIN 43; CONNEXINS; DNA-BINDING PROTEINS; ENDOTHELIAL CELLS; HUMANS; MICE; MUSCLE PROTEINS; NEOVASCULARIZATION, PHYSIOLOGIC; TRANSCRIPTION FACTORS;

EID: 84864280968     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.250159     Document Type: Article

References (28)

1. Dejana E, Taddei A, Randi AM. Foxs and Ets in the transcriptional regulation of endothelial cell differentiation and angiogenesis. Biochim Biophys Acta. 2007;1775:298-312. (Pubitemid 46899342)
2. Kuhnert F, Campagnolo L, Xiong JW, Lemons D, Fitch MJ, Zou Z, Kiosses WB, Gardner H, Stuhlmann H. Dosage-dependent requirement for mouse Vezf1 in vascular system development. Dev Biol. 2005; 283:140-156. (Pubitemid 40828847)
3. Kappel A, Schlaeger TM, Flamme I, Orkin SH, Risau W, Breier G. Role of SCL/Tal-1, GATA, and ets transcription factor binding sites for the regulation of flk-1 expression during murine vascular development. Blood. 2000;96:3078-3085.
4. Fischer A, Schumacher N, Maier M, Sendtner M, Gessler M. The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev. 2004;18:901-911. (Pubitemid 38529659)
5. Yagi R, Kohn MJ, Karavanova I, Kaneko KJ, Vullhorst D, DePamphilis ML, Buonanno A. Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development. Development. 2007;134:3827-3836. (Pubitemid 350187342)
6. Stewart AF, Larkin SB, Farrance IK, Mar JH, Hall DE, Ordahl CP. Muscle-enriched TEF-1 isoforms bind M-CAT elements from muscle-specific promoters and differentially activate transcription. J Biol Chem. 1994;269:3147-3150. (Pubitemid 24237621)
7. Larkin SB, Farrance IK, Ordahl CP. Flanking sequences modulate the cell specificity of M-CAT elements. Mol Cell Biol. 1996;16:3742-3755. (Pubitemid 26199894)
8. Shie JL, Wu G, Wu J, Liu FF, Laham RJ, Oettgen P, Li J. RTEF-1, a novel transcriptional stimulator of vascular endothelial growth factor in hypoxic endothelial cells. J Biol Chem. 2004;279:25010-25016. (Pubitemid 38756749)
9. Connor KM, Krah NM, Dennison RJ, Aderman CM, Chen J, Guerin KI, Sapieha P, Stahl A, Willett KL, Smith LE. Quantification of oxygen-induced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis. Nat Protoc. 2009;4:1565-1573.
10. Ades EW, Candal FJ, Swerlick RA, George VG, Summers S, Bosse DC, Lawley TJ. HMEC-1: establishment of an immortalized human microvascular endothelial cell line. J Invest Dermatol. 1992;99:683-690. (Pubitemid 23002027)
11. An X, Jin Y, Guo H, Foo SY, Cully BL, Wu J, Zeng H, Rosenzweig A, Li J. Response gene to complement 32, a novel hypoxia-regulated angiogenic inhibitor. Circulation. 2009;120:617-627.
12. Geimonen E, Jiang W, Ali M, Fishman GI, Garfield RE, Andersen J. Activation of protein kinase C in human uterine smooth muscle induces connexin-43 gene transcription through an AP-1 site in the promoter sequence. J Biol Chem. 1996;271:23667-23674. (Pubitemid 26327331)
13. Berdichevski A, Meiry G, Milman F, Reiter I, Sedan O, Eliyahu S, Duffy HS, Youdim MB, Binah O. TVP1022 protects neonatal rat ventricular myocytes against doxorubicin-induced functional derangements. J Pharmacol Exp Ther. 2010;332:413-420.
14. +-induced increase in Gap junctional communication between mouse spinal cord astrocytes. J Neurosci. 2001;21:6635-6643. (Pubitemid 32781108)
15. Tirziu D, Chorianopoulos E, Moodie KL, Palac RT, Zhuang ZW, Tjwa M, Roncal C, Eriksson U, Fu Q, Elfenbein A, Hall AE, Carmeliet P, Moons L, Simons M. Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice. J Clin Invest. 2007;117:3188-3197. (Pubitemid 350096977)
16. Meadows KN, Iyer S, Stevens MV, Wang D, Shechter S, Perruzzi C, Camenisch TD, Benjamin LE. Akt promotes endocardial-mesenchyme transition. J Angiogenes Res. 2009;1:2.
17. Smith LE, Wesolowski E, McLellan A, Kostyk SK, D'Amato R, Sullivan R, D'Amore PA. Oxygen-induced retinopathy in the mouse. Invest Ophthalmol Vis Sci. 1994;35:101-111. (Pubitemid 24046832)
18. Lebrin F, Srun S, Raymond K, Martin S, van den Brink S, Freitas C, Bréant C, Mathivet T, Larrivée B, Thomas JL, Arthur HM, Westermann CJ, Disch F, Mager JJ, Snijder RJ, Eichmann A, Mummery CL. Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia. Nat Med. 2010;16:420-428.
19. Teunissen BE, Bierhuizen MF. Transcriptional control of myocardial connexins. Cardiovasc Res. 2004;62:246-255. (Pubitemid 38496538)
20. Johnson TL, Nerem RM. Endothelial connexin 37, connexin 40, and connexin 43 respond uniquely to substrate and shear stress. Endothelium. 2007;14:215-226. (Pubitemid 47543007)
21. Henderson AM, Wang SJ, Taylor AC, Aitkenhead M, Hughes CC. The basic helix-loop-helix transcription factor HESR1 regulates endothelial cell tube formation. J Biol Chem. 2001;276:6169-6176.
22. Birdsey GM, Dryden NH, Amsellem V, Gebhardt F, Sahnan K, Haskard DO, Dejana E, Mason JC, Randi AM. Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin. Blood. 2008;111:3498-3506.
23. Deleuze V, Chalhoub E, El-Hajj R, Dohet C, Le Clech M, Couraud PO, Huber P, Mathieu D. TAL-1/SCL and its partners E47 and LMO2 up-regulate VE-cadherin expression in endothelial cells. Mol Cell Biol. 2007;27:2687-2697. (Pubitemid 46581358)
24. Bény JL. Information Networks in the Arterial Wall. News Physiol Sci. 1999;14:68-73.
25. Figueroa XF, Duling BR. Gap junctions in the control of vascular function. Antioxid Redox Signal. 2009;11:251-266.
26. Lin JH, Takano T, Cotrina ML, Arcuino G, Kang J, Liu S, Gao Q, Jiang L, Li F, Lichtenberg-Frate H, Haubrich S, Willecke K, Goldman SA, Nedergaard M. Connexin 43 enhances the adhesivity and mediates the invasion of malignant glioma cells. J Neurosci. 2002;22:4302-4311. (Pubitemid 37465645)
27. Chen HH, Baty CJ, Maeda T, Brooks S, Baker LC, Ueyama T, Gursoy E, Saba S, Salama G, London B, Stewart AF. Transcription enhancer factor-1-related factor-transgenic mice develop cardiac conduction defects associated with altered connexin phosphorylation. Circulation. 2004;110:2980-2987. (Pubitemid 39491987)
28. Bobbie MW, Roy S, Trudeau K, Munger SJ, Simon AM, Roy S. Reduced connexin 43 expression and its effect on the development of vascular lesions in retinas of diabetic mice. Invest Ophthalmol Vis Sci. 2010;51:3758-3763.