Novel diagnostics of metabolic dysfunction detected in breath and plasma by selective isotope-assisted labeling

Metabolism: Clinical and Experimental

Volumn 61, Issue 8, 2012, Pages 1162-1170

  Haviland, Julia A ^a   Tonelli, Marco ^a   Haughey, Dermot T ^b   Porter, Warren P ^a   Assadi Porter, Fariba M ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Department of Biochemistry ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CARBON 13; CARBON DIOXIDE; GLUCOCORTICOID; GLUCOSE; HYDROCORTISONE; PENTOSE PHOSPHATE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREATHING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIET RESTRICTION; FEMALE; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; GLYCOLYSIS; ISOTOPE LABELING; METABOLIC DISORDER; METABOLISM; METABOLOMICS; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION; PLASMA; PRIORITY JOURNAL;

ALUMINUM OXIDE; ANIMALS; BLOOD GLUCOSE; BREATH TESTS; CARBON ISOTOPES; DISEASE MODELS, ANIMAL; DRUG COMBINATIONS; FEMALE; GLUCOCORTICOIDS; GLYCOLYSIS; HYDROCORTISONE; ISOTOPE LABELING; LACTIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; METABOLOMICS; MICE; PENTOSE PHOSPHATE PATHWAY; PLASMA; SILOXANES; SPECTRUM ANALYSIS;

EID: 84864278681     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2011.12.010     Document Type: Article

References (33)

1. D.J. Barker The fetal and infant origins of adult disease BMJ 301 1990 1111 (Pubitemid 20387183)
2. E.C. Cottrell, and J.R. Seckl Prenatal stress, glucocorticoids and the programming of adult disease Front Behav Neurosci 3 2009 1 9
3. A. Harris, and J. Seckl Glucocorticoids, prenatal stress and the programming of disease Horm Behav 59 2011 279 289
4. J.R. Seckl Prenatal glucocorticoids and long-term programming Eur J Endocrinol 151 Suppl 3 2004 49 62
5. J.R. Seckl, and M.J. Meaney Glucocorticoid programming Ann N Y Acad Sci 1032 2004 63 84 (Pubitemid 40298461)
6. K. O'Brien, H. Sekimoto, and C. Boney Effect of fetal dexamethasone exposure on the development of adult insulin sensitivity in a rat model J Matern Fetal Neonatal Med 21 2008 623 628
7. M.C. Sugden, M.L. Langdown, and M.J. Munns Maternal glucocorticoid treatment modulates placental leptin and leptin receptor expression and materno-fetal leptin physiology during late pregnancy, and elicits hypertension associated with hyperleptinaemia in the early-growth-retarded adult offspring Eur J Endocrinol 145 2001 529 539 (Pubitemid 32927083)
8. C.J. Stocker, J.R. Arch, and M.A. Cawthorne Fetal origins of insulin resistance and obesity Proc Nutr Soc 64 2005 143 151 (Pubitemid 40813536)
9. M.J. Nyirenda Prenatal programming of metabolic syndrome in the common marmoset is associated with increased expression of 11beta-hydroxysteroid dehydrogenase type 1 Diabetes 58 2009 2873 2879
10. A. Jones Fetal growth and the adrenocortical response to psychological stress J Clin Endocrinol Metab 91 2006 1868 1871
11. M.E. Cleasby, P.A. Kelly, and B.R. Walker Programming of rat muscle and fat metabolism by in utero overexposure to glucocorticoids Endocrinology 144 2003 999 1007 (Pubitemid 36262867)
12. J. Hauser Effects of prenatal dexamethasone treatment on postnatal physical, endocrine, and social development in the common marmoset monkey Endocrinology 148 2007 1813 1822 (Pubitemid 46457098)
13. M. Bose, B. Oliván, and B. Laferrère Stress and obesity: the role of the hypothalamic-pituitary-adrenal axis in metabolic disease Curr Opin Endocrinol Diabetes 16 2009 340 346
14. R. Pasquali, V. Vicennati, and M. Cacciari The hypothalamic-pituitary- adrenal axis activity in obesity and the metabolic syndrome Ann N Y Acad Sci 1083 2006 111 128 (Pubitemid 44955469)
15. A.G. Nieuwenhuizen, and F. Rutters The hypothalamic-pituitary-adrenal- axis in the regulation of energy balance Physiol Behav 94 2008 169 177 (Pubitemid 351615426)
16. J.C. Chapman, S.H. Min, and S.M. Freeh The estrogen-injected female mouse: new insight into the etiology of PCOS Reprod Biol Endocrinol 7 2009 47
17. 2 yields from glucose-1- and -6-C14 for the evaluation of the pathways of glucose metabolism J Biol Chem 238 1963 517 523
18. H.G. Wood, J. Katz, and B.R. Landau Estimation of pathways of carbohydrate metabolism Biochem 338 1963 809 847
19. J. Katz, and H.G. Wood The use of glucose-C14 for the evaluation of the pathways of glucose metabolism J Biol Chem 235 1960 2165 2177
20. B. Christensen, T. Christiansen, and A.K. Gombert Simple and robust method for estimation of the split between the oxidative pentose phosphate pathway and the Embden-Meyerhof-Parnas pathway in microorganisms Biotechnol Bioeng 74 2001 517 523 (Pubitemid 32821756)
21. W. Eisenreich, C. Ettenhuber, and R. Laupitz Isotopolog perturbation techniques for metabolic networks: metabolic recycling of nutritional glucose in Drosophila melanogaster Proc Natl Acad Sci U S A 101 2004 6764 6769 (Pubitemid 38586048)
22. 13C NMR spectrometry Biophys Bioeng Lett 2 2009 1 19
23. 2 breath tests Am J Clin Nutr 33 1980 2375 2385
24. 2 in breath due to lipopolysaccharide-induced acute phase response Rapid Commun Mass Spectrom 23 2009 3729 3735
25. H. Kogler, O.W. Sorensen, and G. Bodenhausen Low-pass J filters. Suppression of neighbor peaks in heteronuclear relayed correlation spectra J Magn Reson 55 1983 157 163
26. W.J. Johnson, and J.D. McColl 6-Aminonicotinamide - a potent nicotinamide antagonist Science 122 1955 834
27. P. Jiang p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase Nat Cell Biol 3 2011 310 316
28. M. MÖhlig, J. Spranger, and M. Ristow Predictors of abnormal glucose metabolism in women with polycystic ovary syndrome Eur J Endocrinol 154 2006 295 301
29. C. Besse, N. Nicod, and T. Tappy Changes in insulin secretion and glucose metabolism induced by dexamethasone in lean and obese females Hum Physiol Obes Res 13 2005 306 311
30. 13C-labeled gluconate tracing as a direct and accurate method for determining the pentose phosphate pathway split ratio in Penicillium chrysogenum Appl Environ Microbiol 72 2006 4743 4754 (Pubitemid 44078800)
31. 2 J Appl Physiol 74 1993 133 138 (Pubitemid 23059736)
32. 12C ratios of blood proteins BBRC 212 1995 719 726
33. 2 Biomed Mass Spectrom 11 1984 557 561 (Pubitemid 15157334)