메뉴 건너뛰기




Volumn 586, Issue 16, 2012, Pages 2396-2403

MiR-376a suppresses proliferation and induces apoptosis in hepatocellular carcinoma

Author keywords

HCC; MicroRNA; miR 376a; p85

Indexed keywords

ALPHA FETOPROTEIN; MICRORNA; MICRORNA 376A; PROTEIN P85; PROTEIN P85 ALPHA; UNCLASSIFIED DRUG;

EID: 84864276787     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.05.054     Document Type: Article
Times cited : (68)

References (36)
  • 1
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 4
    • 45349108144 scopus 로고    scopus 로고
    • The role of microRNAs in primary liver cancer
    • H. Varnholt The role of microRNAs in primary liver cancer Ann. Hepatol. 7 2 2008 104 113 (Pubitemid 351845519)
    • (2008) Annals of Hepatology , vol.7 , Issue.2 , pp. 104-113
    • Varnholt, H.1
  • 5
    • 80052245751 scopus 로고    scopus 로고
    • Dlk1-Dio3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival
    • J.M. Luk, J. Burchard, and C. Zhang Dlk1-Dio3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival J. Biol. Chem. 286 35 2011 30706 30713
    • (2011) J. Biol. Chem. , vol.286 , Issue.35 , pp. 30706-30713
    • Luk, J.M.1    Burchard, J.2    Zhang, C.3
  • 6
    • 77952528214 scopus 로고    scopus 로고
    • Cancer gene discovery in hepatocellular carcinoma
    • L. Zender, A. Villanueva, and V. Tovar Cancer gene discovery in hepatocellular carcinoma J. Hepatol. 52 6 2010 921 929
    • (2010) J. Hepatol. , vol.52 , Issue.6 , pp. 921-929
    • Zender, L.1    Villanueva, A.2    Tovar, V.3
  • 7
    • 77349092851 scopus 로고    scopus 로고
    • Molecular classification and novel targets in hepatocellular carcinoma: Recent advancements
    • Y. Hoshida, S. Toffanin, and A. Lachenmayer Molecular classification and novel targets in hepatocellular carcinoma: recent advancements Semin. Liver Dis. 30 1 2010 35 51
    • (2010) Semin. Liver Dis. , vol.30 , Issue.1 , pp. 35-51
    • Hoshida, Y.1    Toffanin, S.2    Lachenmayer, A.3
  • 8
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
    • DOI 10.1053/j.gastro.2007.04.061, PII S0016508507007998
    • H.B. EI-Serag, and K.L. Rudolph Hepatocellular carcinoma: epidemiology and molecular carcinogenesis Gastroenterology 132 7 2007 2557 2576 (Pubitemid 46890874)
    • (2007) Gastroenterology , vol.132 , Issue.7 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 9
    • 77956627711 scopus 로고    scopus 로고
    • The role of signaling pathways in the development and treatment of hepatocellular carcinoma
    • S. Whittaker, R. Marais, and A.X. Zhu The role of signaling pathways in the development and treatment of hepatocellular carcinoma Oncogene 29 36 2010 4989 5005
    • (2010) Oncogene , vol.29 , Issue.36 , pp. 4989-5005
    • Whittaker, S.1    Marais, R.2    Zhu, A.X.3
  • 10
    • 27744534653 scopus 로고    scopus 로고
    • Inhibition of P13K/Akt signaling: An emerging paradigm for targeted cancer therapy
    • Y.L. Chen, P.Y. Law, and H.H. Loh Inhibition of PI3K/Akt signaling: an emerging paradigm for targeted cancer therapy Curr. Med. Chem. Anticancer Agents 5 6 2005 575 589 (Pubitemid 41601056)
    • (2005) Current Medicinal Chemistry - Anti-Cancer Agents , vol.5 , Issue.6 , pp. 575-589
    • Chen, Y.L.1    Law, P.-Y.2    Loh, H.H.3
  • 13
    • 48649083369 scopus 로고    scopus 로고
    • Phosphoinositide 3-OH kinase p85α and p110β are essential for androgen receptor transactivation and tumor progression in prostate cancers
    • Q. Zhu, H. Youn, and J. Tang Phosphoinositide 3-OH kinase p85α and p110β are essential for androgen receptor transactivation and tumor progression in prostate cancers Oncogene 27 33 2008 4569 4579
    • (2008) Oncogene , vol.27 , Issue.33 , pp. 4569-4579
    • Zhu, Q.1    Youn, H.2    Tang, J.3
  • 14
    • 79959857459 scopus 로고    scopus 로고
    • Growth of hepatocellular carcinoma in the regenerating liver
    • J.H. Shi, H.S. Huitfeldt, and Z.H. Suo Growth of hepatocellular carcinoma in the regenerating liver Liver Transpl. 17 7 2011 866 874
    • (2011) Liver Transpl. , vol.17 , Issue.7 , pp. 866-874
    • Shi, J.H.1    Huitfeldt, H.S.2    Suo, Z.H.3
  • 15
    • 79952844942 scopus 로고    scopus 로고
    • Liver regeneration associated protein (ALR) exhibits antimetastatic potential in hepatocellular carcinoma
    • R. Dayoub, H. Wagner, and F. Bataille Liver regeneration associated protein (ALR) exhibits antimetastatic potential in hepatocellular carcinoma Mol. Med. 17 3-4 2011 221 228
    • (2011) Mol. Med. , vol.17 , Issue.34 , pp. 221-228
    • Dayoub, R.1    Wagner, H.2    Bataille, F.3
  • 16
    • 77955069295 scopus 로고    scopus 로고
    • Liver regeneration and its impact on post-hepatectomy metastatic tumor recurrence
    • K.A. Paschos, and N.C. Bird Liver regeneration and its impact on post-hepatectomy metastatic tumor recurrence Anticancer Res. 30 6 2010 2161 2170
    • (2010) Anticancer Res. , vol.30 , Issue.6 , pp. 2161-2170
    • Paschos, K.A.1    Bird, N.C.2
  • 17
    • 77951640416 scopus 로고    scopus 로고
    • Comparison of gene expression in hepatocellular carcinoma, liver development, and liver regeneration
    • T. Li, B. Wan, and J. Huang Comparison of gene expression in hepatocellular carcinoma, liver development, and liver regeneration Mol. Genet. Genomics 283 5 2010 485 492
    • (2010) Mol. Genet. Genomics , vol.283 , Issue.5 , pp. 485-492
    • Li, T.1    Wan, B.2    Huang, J.3
  • 18
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-AKT pathway in human cancer
    • I. Vivanco, and C.L. Sawyers The phosphatidylinositol 3-kinase-AKT Pathway in human cancer Nat. Rev. Cancer 2 7 2002 489 501 (Pubitemid 37328931)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.7 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 19
    • 79958851546 scopus 로고    scopus 로고
    • Comprehensive analysis of human microRNA target networks
    • J. Satoh, and H. Tabunoki Comprehensive analysis of human microRNA target networks BioData 4 2011 17
    • (2011) BioData , vol.4 , pp. 17
    • Satoh, J.1    Tabunoki, H.2
  • 20
    • 33745712594 scopus 로고    scopus 로고
    • Why do hubs tend to be essential in protein networks?
    • X. He, and J. Zhang Why do hubs tend to be essential in protein networks? PLoS Genet. 2 6 2006 e88
    • (2006) PLoS Genet. , vol.2 , Issue.6 , pp. 88
    • He, X.1    Zhang, J.2
  • 21
    • 67650710887 scopus 로고    scopus 로고
    • MicroRNA regulatory patterns on the human metabolic network
    • C. Tibiche, and E. Wang MicroRNA regulatory patterns on the human metabolic network Open Syst. Biol. J. 1 1 2008 1 8
    • (2008) Open Syst. Biol. J. , vol.1 , Issue.1 , pp. 1-8
    • Tibiche, C.1    Wang, E.2
  • 22
    • 44649167011 scopus 로고    scopus 로고
    • Characterization of microRNA-regulated protein- protein interaction network
    • C.W. Hsu, H.F. Juan, and H.C. Huang Characterization of microRNA-regulated protein- protein interaction network Proteomics 8 10 2008 1975 1979
    • (2008) Proteomics , vol.8 , Issue.10 , pp. 1975-1979
    • Hsu, C.W.1    Juan, H.F.2    Huang, H.C.3
  • 23
    • 68049135982 scopus 로고    scopus 로고
    • Inhibitory effects of adenovirus mediated Akt1 and PIK3R1 shRNA on the growth of malignant tumor cells in vitro and in vivo
    • Y. Fu, Q. Zhang, and C. Kang Inhibitory effects of adenovirus mediated Akt1 and PIK3R1 shRNA on the growth of malignant tumor cells in vitro and in vivo Cancer Biol. Ther. 8 11 2009 1002 1009
    • (2009) Cancer Biol. Ther. , vol.8 , Issue.11 , pp. 1002-1009
    • Fu, Y.1    Zhang, Q.2    Kang, C.3
  • 24
    • 81155138127 scopus 로고    scopus 로고
    • The role of microRNAs in human liver cancers
    • C. Braconi, J.C. Henry, and T. Kogure The role of microRNAs in human liver cancers Semin. Oncol. 38 6 2011 752 763
    • (2011) Semin. Oncol. , vol.38 , Issue.6 , pp. 752-763
    • Braconi, C.1    Henry, J.C.2    Kogure, T.3
  • 26
    • 79960743857 scopus 로고    scopus 로고
    • Genomewide microRNA down-regulation as a negative feedback mechanism in the early phases of liver regeneration
    • J. Shu, B.T. Kren, and Z. Xia Genomewide microRNA down-regulation as a negative feedback mechanism in the early phases of liver regeneration Hepatology 54 2 2011 609 619
    • (2011) Hepatology , vol.54 , Issue.2 , pp. 609-619
    • Shu, J.1    Kren, B.T.2    Xia, Z.3
  • 27
    • 79751484450 scopus 로고    scopus 로고
    • Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma
    • J. Hou, L. Lin, and W. Zhou Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma Cancer Cell 19 2 2011 232 243
    • (2011) Cancer Cell , vol.19 , Issue.2 , pp. 232-243
    • Hou, J.1    Lin, L.2    Zhou, W.3
  • 29
    • 79961206772 scopus 로고    scopus 로고
    • Regulation of erythroid differentiation by miR-376a and its targets
    • F. Wang, J. Yu, and G.H. Yang Regulation of erythroid differentiation by miR-376a and its targets Cell Res. 21 8 2011 1196 1209
    • (2011) Cell Res. , vol.21 , Issue.8 , pp. 1196-1209
    • Wang, F.1    Yu, J.2    Yang, G.H.3
  • 30
    • 0019809628 scopus 로고
    • Relationship between serum alpha-foetoprotein, cirrhosis and survival in hepatocellular carcinoma
    • P.J. Johnson, W.M. Melia, and M.K. Palmer Relationship between serum alpha-foetoprotein, cirrhosis and survival in hepatocellular carcinoma Br. J. Cancer 44 4 1981 502 505 (Pubitemid 12231984)
    • (1981) British Journal of Cancer , vol.44 , Issue.4 , pp. 502-505
    • Johnson, P.J.1    Melia, W.M.2    Palmer, M.K.3
  • 31
    • 4544301860 scopus 로고    scopus 로고
    • High α-fetoprotein level correlates with high stage, early recurrence and poor prognosis of hepatocellular carcinoma: Significance of hepatitis virus infection, age, p53 and β-catenin mutations
    • DOI 10.1002/ijc.20279
    • S.Y. Peng, W.J. Chen, and P.L. Lai High alpha-fetoprotein level correlates with high stage, early recurrence and poor prognosis of hepatocellular carcinoma: significance of hepatitis virus infection, age, p53 and beta-catenin mutations Int. J. Cancer 112 1 2004 44 50 (Pubitemid 39249490)
    • (2004) International Journal of Cancer , vol.112 , Issue.1 , pp. 44-50
    • Peng, S.-Y.1    Chen, W.J.2    Lai, P.-L.3    Jeng, Y.-M.4    Sheu, J.-C.5    Hsu, H.-C.6
  • 32
    • 80052451056 scopus 로고    scopus 로고
    • Experimental strategies for microRNA target indentification
    • D.W. Thomson, C.P. Bracken, and G.J. Goodall Experimental strategies for microRNA target indentification Nucleic Acid Res. 39 16 2011 6845 6853
    • (2011) Nucleic Acid Res. , vol.39 , Issue.16 , pp. 6845-6853
    • Thomson, D.W.1    Bracken, C.P.2    Goodall, G.J.3
  • 33
  • 34
    • 0033556333 scopus 로고    scopus 로고
    • Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85α
    • D.A. Fruman, S.B. Snapper, and C.M. Yballe Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85α Science 283 5400 1999 393 397
    • (1999) Science , vol.283 , Issue.5400 , pp. 393-397
    • Fruman, D.A.1    Snapper, S.B.2    Yballe, C.M.3
  • 35
    • 80055023676 scopus 로고    scopus 로고
    • Suppression of the PI3K p85α delays embryoid body development and inhibits cell adhesion
    • S.M. Gurney, P. Forster, and U. Just Suppression of the PI3K p85α delays embryoid body development and inhibits cell adhesion J. Cell. Biochem. 112 12 2011 3573 3581
    • (2011) J. Cell. Biochem. , vol.112 , Issue.12 , pp. 3573-3581
    • Gurney, S.M.1    Forster, P.2    Just, U.3
  • 36
    • 58149215802 scopus 로고    scopus 로고
    • MiR-29 miRNAs activate p53 by targeting p85αand CDC42
    • S.Y. Park, J.H. Lee, and M. Ha MiR-29 miRNAs activate p53 by targeting p85αand CDC42 Nat. Struct. Mol. Biol. 16 1 2009 23 29
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , Issue.1 , pp. 23-29
    • Park, S.Y.1    Lee, J.H.2    Ha, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.