Case 23-2012: A 59-year-old man with abdominal pain and weight loss

New England Journal of Medicine

Volumn 367, Issue 4, 2012, Pages 363-373

  Xavier, Ramnik J ^a,c   Gala, Manish K ^a,c   Bronzo, Brian K ^b,c   Kelly, Paul J ^b,c  

^a Department of Medicine ^*  (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; IVERMECTIN;

ABDOMINAL CRAMP; ABDOMINAL DISCOMFORT; ABDOMINAL PAIN; ABDOMINAL RADIOGRAPHY; ABDOMINAL TENDERNESS; ADULT; ANOREXIA; ARTICLE; CACHEXIA; CASE REPORT; CELIAC DISEASE; CLINICAL EVALUATION; CLINICAL FEATURE; COLONOSCOPY; COMPUTER ASSISTED TOMOGRAPHY; CONSTIPATION; CROHN DISEASE; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; DISEASE EXACERBATION; DUODENUM BIOPSY; ERYTHEMA; ESCHERICHIA COLI INFECTION; GLUTEN FREE DIET; HUMAN; HUMAN TISSUE; LAMINA PROPRIA; LEG SWELLING; MALE; MEDICAL HISTORY; OCCULT BLOOD; PELVIS FRACTURE; PRIORITY JOURNAL; SMALL INTESTINE OBSTRUCTION; STRONGYLE INFECTION; STRONGYLOIDIASIS; THORAX RADIOGRAPHY; VOMITING; WEAKNESS; WEIGHT REDUCTION; ANIMAL; CLINICAL OBSERVATION; CLINICAL STUDY; DIAGNOSIS; HUMAN T CELL LEUKEMIA VIRUS 1; HUMAN T CELL LEUKEMIA VIRUS INFECTION; ISOLATION AND PURIFICATION; JEJUNUM; MIDDLE AGED; PARASITOLOGY; PATHOLOGY; PELVIS; RADIOGRAPHY; STRONGYLOIDES STERCORALIS;

ABDOMINAL PAIN; ANIMALS; DIAGNOSIS, DIFFERENTIAL; HTLV-I INFECTIONS; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; JEJUNUM; MALE; MIDDLE AGED; PELVIS; RADIOGRAPHY, ABDOMINAL; STRONGYLOIDES STERCORALIS; STRONGYLOIDIASIS; TOMOGRAPHY, X-RAY COMPUTED; WEIGHT LOSS;

EID: 84864251526     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcpc1109275     Document Type: Article

References (22)

1. Green PHR, Stavropoulos SN, Panagi SG, et al. Characteristics of adult celiac disease in the USA: results of a national survey. Am J Gastroenterol 2001;96:126-31. (Pubitemid 32104819)
2. Hankey GL, Holmes GK. Coeliac disease in the elderly. Gut 1994;35:65-7. (Pubitemid 24059474)
3. Sulkanen S, Halttunen T, Laurila K, et al. Tissue transglutaminase autoantibody enzyme-linked immunosorbent assay in detecting celiac disease. Gastroenterology 1998;115:1322-8. (Pubitemid 28545980)
4. Marsh MN. Gluten, major histocompatibility complex, and the small intestine: a molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue'). Gastroenterology 1992;102:330-54.
5. Conley ME, Notarangelo LD, Etzioni A. Diagnostic criteria for primary immunodeficiencies: representing PAGID (Pan-American Group for Immunodeficiency) and ESID (European Society for Immunodeficiencies). Clin Immunol 1999;93:190-7.
6. Cunningham-Rundles C, Bodian C. Common variable immunodeficiency: clinical and immunological features of 248 patients. Clin Immunol 1999;92:34-48. (Pubitemid 29315984)
7. Agarwal S, Mayer L. Pathogenesis and treatment of gastrointestinal disease in antibody deficiency syndromes. J Allergy Clin Immunol 2009;124:658-64.
8. Daniels JA, Lederman HM, Maitra A, Montgomery EA. Gastrointestinal tract pathology in patients with common variable immunodeficiency (CVID): a clinicopathologic study and review. Am J Surg Pathol 2007;31:1800-12. (Pubitemid 350175807)
9. Booth CC. The 1st description of tropical sprue (William Hillary). Gut 1964;5:45-50.
10. Klipstein FA, Falaiye JM. Tropical sprue in expatriates from the tropics living in the continental United States. Medicine (Baltimore) 1969;48:475-91.
11. Schenk EA, Samloff IM, Klipstein FA. Morphologic characteristics of jejunal biopsy in celiac disease and tropical sprue. Am J Pathol 1965;47:765-81.
12. Gorbach SL, Mitra R, Jacobs B, Banwell JG, Chatterjee BD, Mazumder DN. Bacterial contamination of the upper small bowel in tropical sprue. Lancet 1969;1:74-7.
13. Farmer RG, Hawk WA, Turnbull RB Jr. Clinical patterns in Crohn's disease: a statistical study of 615 cases. Gastroenterology 1975;68:627-35.
14. Franke A, McGovern DP, Barrett JC, et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet 2010;42:1118-25.
15. Kurata JH, Kantor-Fish S, Frankl H, Godby P, Vadheim CM. Crohn's disease among ethnic groups in a large health maintenance organization. Gastroenterology 1992;102:1940-8.
16. Khalili H, Huang ES, Ananthakrishnan AN, et al. Geographical variation and incidence of inflammatory bowel disease among US women. Gut 2012 January 11 (Epub ahead of print).
17. Genta RM. Global prevalence of strongyloidiasis: critical review with epidemiologic insights into the prevention of disseminated disease. Rev Infect Dis 1989;11:755-67.
18. Carvalho BS, Louis TA, Irizarry RA. Quantifying uncertainty in genotype calls. Bioinformatics 2010;26:242-9.
19. de Thé G, Bomford R. An HTLV-I vaccine: why, how, for whom? AIDS Res Hum Retroviruses 1993;9:381-6.
20. Porto AF, Neva FA, Bittencourt H, et al. HTLV-1 decreases Th2 type of immune response in patients with strongyloidiasis. Parasite Immunol 2001;23:503-7. (Pubitemid 34205735)
21. Mirdha BR. Human strongyloidiasis: often brushed under the carpet. Trop Gastroenterol 2009;30:1-4.
22. Thompson BF, Fry LC, Wells CD, et al. The spectrum of GI strongyloidiasis: an endoscopic-pathologic study. Gastrointest Endosc 2004;59:906-10. (Pubitemid 38879326)