Targeted cancer treatment using Anti-EGFR and-TFR antibody-conjugated gold nanoparticles stimulated by nonthermal air plasma

Plasma Medicine

Volumn 1, Issue 2, 2011, Pages 179-188

  Kim, G J ^a   Park, S R ^b   Kim, G C ^b   Lee, J K ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b Pusan National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AIR PLASMAS; ANTI-EGFR; CANCER CELLS; CANCEROUS CELLS; DEATH RATES; GOLD NANOPARTICLES; GROWTH FACTOR; NONTHERMAL; ORAL CANCER; PLASMA THERAPY; PLASMA TREATMENT; TRANSFERRIN RECEPTORS; TREATMENT PROCESS;

CELLS; CYTOLOGY; DISEASES; METAL NANOPARTICLES; PLASMA APPLICATIONS; PLASMAS;

ANTIBODIES;

ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; GOLD NANOPARTICLE; POLITEF; TRANSFERRIN RECEPTOR; TRANSFERRIN RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY SPECIFICITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER THERAPY; CELL ASSAY; CELL DEATH; CELL KILLING; CELL SPECIFICITY; CONTROLLED STUDY; DRUG BINDING; DRUG CONJUGATION; DRUG EFFICACY; DRUG TARGETING; ELECTRIC POTENTIAL; ELECTRODE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MELANOMA CELL; MOUSE; MOUTH SQUAMOUS CELL CARCINOMA; NONHUMAN; NONTHERMAL AIR PLASMA; PLASMA GAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STIMULATION;

EID: 84864242227     PISSN: 19475764     EISSN: 19475772     Source Type: Journal    
DOI: 10.1615/PlasmaMed.v1.i2.70     Document Type: Article

References (13)

1. D'Silva NJ, Ward BB. Tissue biomarkers for diagnosis & management of oral squamous cell carcinoma. Alpha Omegan. 2007;100(4):182-9.
2. Fridman G, Jost MM, Brooks AD, Fridman A, Gutsol A, Vasilets V, Friedman G. Floating electrode dielectric barrier discharge plasma in air promoting apoptotic behavior in melanoma skin cancer cell lines. Plasma Chem Plasma Process. 2007;27(2):163-76.
3. Service RF. Materials and biology. Nanotechnology takes aim at cancer. Science. 2005;310(5751):1132-4.
4. Rayavarapu RG, Petersen W, Ungureanu C, Post JN, van Leeuwen TG, Manohar S. Synthesis and bioconjugation of gold nanoparticles as potential molecular probes for light-based imaging techniques. Int J Biomed Imaging 2007;2007:29817.
5. Kim GC, Kim GJ, Park SR, Jeon SM, Seo HJ, Iza F, Lee JK. Air plasma coupled with antibody conjugated nanoparticles: A new weapon against cancer. J Phys D. 2009;42(3):032005.
6. Daniels TR, Delgado T, Rodriguez JA, Helguera G, Penichet ML. The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer. Clin Immunol. 2006;121(2):144-58.
7. Daniels TR, Delgado T, Helguera G, Penichet ML. The transferrin receptor part II: Targeted delivery of therapeutic agents into cancer cells. Clin Immunol. 2006;121(2):159-76.
8. Herbst RS. Review of epidermal growth factor receptor biology. Int J Radiat Oncol Biol Phys. 2004;59(2 suppl 1):S21-6.
9. Kim GJ, Kim W, Kim KT, Lee JK. DNA damage and mitochondria dysfunction in cell apoptosis induced by nonthermal air plasma. Appl Phys Lett. 2010;96:021502
10. Phillips DM. Determination of gas temperature from unresolved bands in the spectrum from a nitrogen discharge. J Phys D. 1976;9(3):507-21.
11. Ennis BW, Lippman ME, Dickson RB. The EGF receptor system as a target for antitumor therapy. Cancer Invest. 1991;9(5):553-62.
12. Herbst RS, Langer CJ. Epidermal growth factor receptors as a target for cancer treatment: the emerging role of IMC-C225 in the treatment of lung and head and neck cancers. Semin Oncol. 2002;(1 Suppl 4):27-36.
13. Kondapaka SB, Fridman R, Reddy KB. Epidermal growth factor and amphiregulin upregulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells. Int J Cancer. 1997;70(6):722-6.