Intranasal ketorolac tromethamine (SPRIX®) containing 6% of lidocaine (ROX-828) for acute treatment of migraine: Safety and efficacy data from a phase II clinical trial

Cephalalgia

Volumn 32, Issue 10, 2012, Pages 766-777

  Pfaffenrath, V ^a   Fenzl, E ^b   Bregman, D ^c,d   Farkkila M ^e  

^a Neurological Practice   (Germany)

^b FGK Clinical Research   (Germany)

^c Luitpold Pharmaceuticals   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Intranasal; moderate to severe pain; nonsteroidal anti inflammatory; nontriptan

Indexed keywords

KETOROLAC TROMETAMOL; LIDOCAINE; PLACEBO; ROX 828; UNCLASSIFIED DRUG;

ADULT; ARM NUMBNESS; ARTICLE; BLOOD CHEMISTRY; CONTROLLED STUDY; DISEASE SEVERITY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG FORMULATION; DRUG SAFETY; DRUG SELF ADMINISTRATION; DRUG TOLERABILITY; DYSGEUSIA; ELECTROCARDIOGRAM; FATIGUE; FEMALE; HUMAN; HYPESTHESIA; INTRANASAL HYPOESTHESIA; KAPLAN MEIER METHOD; LEG NUMBNESS; MAJOR CLINICAL STUDY; MALE; MIGRAINE WITH AURA; MIGRAINE WITHOUT AURA; MULTICENTER STUDY; NASAL DISCOMFORT; NAUSEA; NOSE CONGESTION; NOSE DISEASE; ORAL HYPOESTHESIA; PARESTHESIA; PHARYNGEAL HYPOESTHESIA; PHASE 2 CLINICAL TRIAL; PHONOPHOBIA; PHOTOPHOBIA; RANDOMIZED CONTROLLED TRIAL; RHINALGIA; SIDE EFFECT; SYMPTOM; TREATMENT OUTCOME; VITAL SIGN; VOMITING;

ADMINISTRATION, INTRANASAL; ADOLESCENT; ADULT; ANESTHETICS, LOCAL; CYCLOOXYGENASE INHIBITORS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; KETOROLAC TROMETHAMINE; LIDOCAINE; MALE; MIDDLE AGED; MIGRAINE DISORDERS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84864191546     PISSN: 03331024     EISSN: 14682982     Source Type: Journal    
DOI: 10.1177/0333102412451359     Document Type: Article

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