Bioimpedance analysis for the characterization of breast cancer cells in suspension

IEEE Transactions on Biomedical Engineering

Volumn 59, Issue 8, 2012, Pages 2321-2329

  Qiao, Guofeng ^a   Wang, Wei ^a   Duan, Wei ^a   Zheng, Fan ^a   Sinclair, Alison J ^a   Chatwin, Chris R ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

Breast cancer cells; cancer identification; impedance spectroscopy

Indexed keywords

BIO-IMPEDANCE; BIOIMPEDANCE ANALYSIS; BIOIMPEDANCE MEASUREMENT; BREAST CANCER; BREAST CANCER CELLS; CANCER CELLS; CELL LINES; CELL SUSPENSION; CELL TYPES; CELLULAR INFORMATION; CELLULAR LEVELS; CHARACTERISTIC FREQUENCIES; DIFFERENT FREQUENCY; ELECTRICAL PARAMETER; ELECTRICAL RESISTANCES; EQUIVALENT CIRCUIT MODEL; IMPEDANCE ANALYZER; IMPEDANCE MEASUREMENT; IMPEDANCE SPECTROSCOPY; LABORATORY CONDITIONS; LOW FREQUENCY; PHYSICAL MODEL;

CELL CULTURE; DISEASES; ELECTRIC IMPEDANCE MEASUREMENT; HISTOLOGY; MODELS; TISSUE;

ELECTRIC PROPERTIES;

ARTICLE; BIOIMPEDANCE SPECTROSCOPY; BREAST CANCER; CANCER CELL; CANCER STAGING; CELL SUSPENSION; ELECTRODE; HUMAN; HUMAN CELL; IMPEDANCE; SPECTROSCOPY;

BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; CYTOLOGICAL TECHNIQUES; DIELECTRIC SPECTROSCOPY; ELECTRIC IMPEDANCE; FEMALE; HUMANS; SUSPENSIONS;

EID: 84864190467     PISSN: 00189294     EISSN: 15582531     Source Type: Journal    
DOI: 10.1109/TBME.2012.2202904     Document Type: Article

References (49)

1. A. J. Surowiec et al., "Dielectric properties of breast carcinoma and the surrounding tissues," IEEE Trans. Biomed. Eng., vol. 35, no. 4, pp. 257- 63, Apr. 1988.
2. J. Jossinet and M. Schmitt, "A review of parameters for the bioelectrical characterization ofbreasttissue," Ann. N. Y. Acad. Sci., vol. 873, pp. 30- 41, Apr. 20, 1999. (Pubitemid 29263645)
3. R. J. Halter et al., "Electrical impedance spectroscopy of benign and malignant prostatic tissues," J. Urol., vol. 179, pp. 1580-1586, Apr. 2008.
4. D. Haemmerich etal., "In vivo electrical conductivity ofhepatic tumours," Physiol. Meas., vol. 24, pp. 251-260, May 2003.
5. B. Tunstall et al., "An analysis of systematic errors in the electrical impedance measurement of tissue characteristics during an in-vitro study in the frequency range 1 kHz to 4 MHz," in Proc. IEEE 19th Annu. Int. Conf. Eng. Med. Biol. Soc., Oct./Nov. 1997, vol. 2, pp. 860-862.
6. K. R. Foster and H. P. Schwan, "Dielectric properties of tissues and bi- ological materials: A critical review," Crit. Rev. Biomed. Eng., vol. 17, pp. 25-104, 1989.
7. T. J. Faes et al., "The electric resistivity of human tissues (100 Hz- 10 MHz): A meta-analysis of review studies," Physiol. Meas., vol. 20, pp. R1-R10, Nov. 1999.
8. A. Swarup et al., "Dielectric properties of mouse MCA1 fibrosarcoma at different stages of development," Bioelectromagnetics, vol. 12, pp. 1-8, 1991.
9. C. Gabriel et al., "The dielectric properties of biological tissues-Part I: Literature survey," Phys. Med. Biol., vol. 41, pp. 2231-2249, Nov. 1996. (Pubitemid 26376901)
10. M. R. Stoneman et al., "Correction of electrode polarization contributions to the dielectric properties of normal and cancerous breast tissues at au- dio/radiofrequencies," Phys. Med. Biol., vol. 52, pp. 6589-6604, Nov. 2007. (Pubitemid 350058949)
11. I. O. K'Owino and O. A. Sadik, "Impedance spectroscopy: A powerful tool for rapid biomolecular screening and cell culture monitoring," Electroanalysis, vol. 17, pp. 2101-2113, 2005. (Pubitemid 41810053)
12. A. Rothermel et al., "Real-time measurement of PMA-induced cellu- lar alterations by microelectrode array-based impedance spectroscopy," Biotechniques, vol. 41, pp. 445-450, Oct. 2006. (Pubitemid 46534883)
13. Y. B. Li and M. Varshney, "Interdigitated array microelectrodes based impedance biosensors for detection of bacterial cells," Biosens. Bioelec- tron., vol. 24, pp. 2951-2960, Jun. 2009.
14. S. M. Radke and E. C. Alocilja, "A high density microelectrode array biosensor for detection of E. coli O157:H7," Biosens. Bioelectron., vol. 20, pp. 1662-1667, Feb. 2005. (Pubitemid 40051257)
15. J. H. Yeon and J. K. Park, "Cytotoxicity test based on electrochemical impedance measurement of HepG2 cultured in microfabricated cell chip," Anal. Biochem., vol. 341, pp. 308-15, Jun. 2005.
16. E. Moore et al., "Monitoring of cell growth in vitro using biochips pack- agedwithindiumtinoxidesensors," Sens. Actuators B-Chem.,vol. 139, pp. 187-193, May 2009.
17. S. Suresh, "Biomechanics and biophysics of cancer cells," Acta Biomater., vol. 3, pp. 413-38, Jul. 2007. (Pubitemid 46865787)
18. M. Abercrombie and E. J. Ambrose, "The surface properties of cancer cells: A review," Cancer Res., vol. 22, pp. 525-548, Jun. 1962. 19 S. Cho and H. Thielecke, "Micro hole-based cell chip with impedance spectroscopy," Biosens. Bioelectron., vol. 22, pp. 1764-1768, Mar. 2007.
19. L. S. Jang and M. H. Wang, "Microfluidic device for cell capture and impedance measurement," Biomed. Microdevices, vol. 9, pp. 737-743, Oct. 2007.
20. D. Malleo et al., "Continuous differential impedance spectroscopy of single cells," Microfluid Nanofluid., vol. 9, pp. 191-198, Aug. 2010.
21. C. M. Kurzetal., "Chip-basedimpedance measurement on single cells for monitoring sub-toxic effects on cell membranes," Biosens. Bioelectron., vol. 26, pp. 3405-3412, Apr. 15, 2011.
22. F. Asphahani et al., "Single-cell bioelectrical impedance platform for monitoring cellular response to drug treatment," Phys. Biol., vol. 8, pp. 015006-015017, Feb. 2011.
23. A. Han et al., "Quantification of the heterogeneity in breast cancer cell lines using whole-cell impedance spectroscopy," Clin. Cancer Res., vol. 13, pp. 139-143, Jan. 2007. (Pubitemid 46121862)
24. H. P. Schwan, "Linear and nonlinear electrode polarization and biological- materials," Ann. Biomed. Eng., vol. 20, pp. 269-288, 1992.
25. S. Bhansali et al., "Effect of electrode geometry on the impedance eval- uation of tissue and cell culture," Sens. Actuators B-Chem., vol. 127, pp. 89-96, Oct. 2007. (Pubitemid 47503708)
26. H. Griffiths et al., "An electrical impedance tomography microscope," Physiol. Meas., vol. 17, no. Suppl 4A, pp. A15-A24, Nov. 1996.
27. H. P. Schwan, "Electrical properties of tissue and cell suspensions," Adv. Biol. Med. Phys., vol. 5, pp. 147-209, 1957.
28. T. Hanai et al., "Dielectric theory of concentrated suspensions of shell- spheres in particular referenc to the analysis of biological cell suspen- sions," Bull. Inst. Chem. Res., vol. 57, pp. 279-305, 1979.
29. K. Asami, "Characterization of heterogeneous systems by dielectric spec- troscopy," Prog. Polym. Sci., vol. 27, pp. 1617-1659, 2002. (Pubitemid 34808609)
30. H. Pauly et al., "Electrical properties of mitochondrial membranes," J. Biophys. Biochem. Cytol., vol. 7, pp. 589-601, 1960.
31. K. Asami et al., "Dielectric-properties of mouse lymphocytes and ery- throcytes," Biochim. Et Biophy. Acta, vol. 1010, pp. 49-55, Jan. 1989. (Pubitemid 19050004)
32. K. Asami et al., "Dielectric properties of yeast cells," J. Membr. Biol., vol. 28, pp. 169-180, Aug. 1976.
33. V. Raicu et al., "Dielectric properties of yeast cells as simulated by the two-shell model," Biochim. EtBiophy. Acta, vol. 1274, pp. 143-148, Jun. 1996. (Pubitemid 26194102)
34. W. Bai et al., "Dielectric properties of E. coli cell as simulated by the three-shell spheroidal model," Biophys. Chem., vol. 122, pp. 136-142, Jul. 2006. (Pubitemid 43994290)
35. K. Zhao et al., "Dielectric spectroscopy of Anabaena 7120 protoplast suspensions," Bioelectrochem., vol. 69, pp. 49-57, Sep. 2006. (Pubitemid 44287611)
36. A. Ron et al., "Dielectric screening of early differentiation patterns in mesenchymal stem cells induced by steroid hormones," Bioelectrochem., vol. 78, pp. 161-172, Jun. 2010.
37. W. Niewiadomski et al., "Ion concentration and haematocrit as determi- nants of impedance in an erythrocyte suspension model of renal medullary tissue," Phys. Med. Biol., vol. 35, pp. 1575-1583, Nov. 1990. (Pubitemid 20368992)
38. Y. Hayashietal., "Dielectricinspectionoferythrocytemorphology," Phys. Med. Biol., vol. 53, pp. 2553-2564, May 21, 2008.
39. M. Stoneman et al., "Protein influence on the plasma membrane dielectric properties: In vivo study utilizing dielectric spectroscopy and fluorescence microscopy," Bioelectrochem., vol. 70, pp. 542-550, May 2007. (Pubitemid 46507986)
40. C. Bot and C. Prodan, "Probing the membrane potential ofliving cells by dielectric spectroscopy," Eur. Biophys. J., vol. 38, pp. 1049-1059, Oct. 2009.
41. V. Raicu et al., "Dielectric properties of rat liver in vivo: Analysis by mod- eling hepatocytes in the tissue architecture," Bioelectrochem. Bioenerg., vol. 47, pp. 333-342, Dec. 1998. (Pubitemid 29057716)
42. G. Qiao etal., "Electrical properties of breast cancer cells fromimpedance measurement of cell suspensions," J. Phys.: Conf. Ser., vol. 224, pp. 012081-012084, 2010.
43. P. R. Gascoyne et al., "Dielectrophoretic separation of cancer cells from blood," IEEE Trans. Ind. Appl., vol. 33, no. 3, pp. 670-678, May/Jun. 1997. (Pubitemid 127828225)
44. F. H. Labeed et al., "Differences in the biophysical properties of mem- brane and cytoplasm of apoptotic cells revealed using dielectrophoresis, " Biochim. Biophys. Acta, vol. 1760, pp. 922-929, Jun. 2006. (Pubitemid 43816174)
45. K. S. Cole and R. H. Cole, "Dispersion and absorption in dielectrics I. Alternating current characteristics," J. Chem. Phys., vol. 9, pp. 341-351, 1941. 47 H. P. Schwan and H. J. Morowitz, "Electrical properties of the mem-branes of the pleuropneumonia-like organism A 5969," Biophys. J., vol. 2, pp. 395-407, Sep. 1962.
46. R. A. Hoffman and W. B. Britt, "Flow-system measurement of cell impedance properties," J. Histochem. Cytochem., vol. 27, pp. 234-240, Jan. 1979.
47. A. Irimajiri et al., "Passive electrical properties of the membrane and cyto-plasm of cultured rat basophil leukemia cells-Part I: Dielectric behavior of cell suspensions in 0.01-500 MHz and its simulation with a single-shell model," Biochim. EtBiophy. Acta, vol. 896, pp. 203-213, Jan. 1987. (Pubitemid 17002014)
48. Q. Li and C. T. Lim, "Structure-mechanical property changes in nucleus arising from breast cancer," in Cell. Biomol. Mech. Mechanobiol., Vol. 4, A. Gefen, Ed. Berlin, Germany: Springer, 2011, pp. 465-475.
49. D.Zinketal.,"Nuclearstructureincancercells," Nat.Rev. Cancer,vol.4, pp. 677-687, Sep. 2004.