Accurate risk-based chemical screening relies on robust exposure estimates

Toxicological Sciences

Volumn 128, Issue 1, 2012, Pages 295-296

  Rudel, Ruthann ^a   Perovich, Laura ^a  

^a Silent Spring Institute   (United States)

Author keywords

Exposure measurements; Extreme values; Inter individual variation; Nhanes; Risk assessment

Indexed keywords

ATRAZINE; CACODYLIC ACID; CHLORINE; DIMPYLATE; LINDANE; MERCURY; PESTICIDE; TRICLOSAN;

BIOLOGICAL MONITORING; GENETIC VARIABILITY; HEALTH CARE SURVEY; HUMAN; IN VITRO STUDY; LETTER; POPULATION EXPOSURE; RISK ASSESSMENT; SCREENING TEST;

ANIMALS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MODELS, BIOLOGICAL; SMALL MOLECULE LIBRARIES; TOXICITY TESTS;

EID: 84864132246     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs143     Document Type: Letter

References (3)

1. National Center for Health Statistics (NCHS)/CDC. (2012). Maxima and Unweighted 95th Percentile from National Health and Nutrition Examination Survey Data. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 1999-2010, Hyattsville, MD. Available at: //ftp.cdc.gov/pub/health_statistics/nchs/nhanes/. Accessed March 20, 2012.
2. US CDC. (2009). Fourth National Report on Human Exposure to Environmental Chemicals.
3. Wetmore, B. A., Wambaugh, J. F., Ferguson, S. S., Sochaski, M. A., Rotroff, D. M., Freeman, K., Clewell, H. J., III, Dix, D. J., Andersen, M. E., Houck, K. A., et al. (2012). Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment. Toxicol. Sci. 125, 157-174.