Bupropion versus methylphenidate in the treatment of children with attention-deficit/hyperactivity disorder: Randomized double-blind study

Human Psychopharmacology

Volumn 27, Issue 4, 2012, Pages 411-418

  Jafarinia, Morteza ^a   Mohammadi, Mohammad Reza ^a   Modabbernia, Amirhossein ^a   Ashrafi, Mandana ^a   Khajavi, Danial ^a   Tabrizi, Mina ^b   Yadegari, Noorollah ^a   Akhondzadeh, Shahin ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

adolescent; attention deficit hyperactivity disorder; bupropion; children; methylphenidate

Indexed keywords

AMFEBUTAMONE; METHYLPHENIDATE;

ABDOMINAL PAIN; ADOLESCENT; AGITATION; ANXIETY; ARTICLE; ATTENTION DEFICIT DISORDER; ATTENTION DEFICIT HYPERACTIVITY DISORDER RATING SCALE IV; CHILD; CHILDHOOD DISEASE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DECREASED APPETITE; DIZZINESS; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG SAFETY; DSM-IV-TR; FEMALE; FISHER EXACT TEST; HUMAN; INSOMNIA; INTERVIEW; MAJOR CLINICAL STUDY; MALE; NERVOUSNESS; PARENT SCALE; PRESCHOOL CHILD; PRIORITY JOURNAL; RATING SCALE; SCHOOL CHILD; SIDE EFFECT; TACHYCARDIA; THERAPY EFFECT; TREATMENT RESPONSE; VOMITING; XEROSTOMIA;

ADOLESCENT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BUPROPION; CHILD; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HEADACHE; HUMANS; MALE; METHYLPHENIDATE; PSYCHIATRIC STATUS RATING SCALES; TREATMENT OUTCOME;

EID: 84864128978     PISSN: 08856222     EISSN: 10991077     Source Type: Journal    
DOI: 10.1002/hup.2242     Document Type: Article

References (38)

1. Ahmann PA, Waltonen SJ, Olson KA, Theye FW, Van Erem AJ, Laplant RJ,. 1993. Placebo-controlled evaluation of Ritalin side effects. Pediatrics 91: 1101-1106.
2. Akhondzadeh S, Tavakolian R, Davari-Ashtiani R, Arabgol F, Amini H,. 2003. Selegiline in the treatment of attention deficit hyperactivity disorder in children: a double blind and randomized trial. Prog Neuropsychopharmacol Biol Psychiatry 27: 841-845.
3. Akhondzadeh S, Mohammadi MR, Khademi M,. 2004. Zinc sulfate as an adjunct to methylphenidate for the treatment of attention deficit hyperactivity disorder in children: a double blind and randomized trial [ISRCTN64132371]. BMC Psychiatry 4: 9.
4. Amiri S, Mohammadi MR, Mohammadi M, Nouroozinejad GH, Kahbazi M, Akhondzadeh S,. 2008. Modafinil as a treatment for Attention-Deficit/ Hyperactivity Disorder in children and adolescents: a double blind, randomized clinical trial. Prog Neuropsychopharmacol Biol Psychiatry 32: 145-149.
5. Arnsten AF,. 2006. Stimulants: therapeutic actions in ADHD. Neuropsychopharmacology 31: 2376-2383.
6. Ascher JA, Cole JO, Colin JN, et al,. 1995. Bupropion: a review of its mechanism of antidepressant activity. J Clin Psychiatry 56: 395-401.
7. Banaschewski T, Roessner V, Dittmann RW, Santosh PJ, Rothenberger A,. 2004. Non-stimulant medications in the treatment of ADHD. Eur Child Adolesc Psychiatry 13 (Suppl 1): I102-I116.
8. Barrickman LL, Perry PJ, Allen AJ, et al,. 1995. Bupropion versus methylphenidate in the treatment of attention-deficit hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 34: 649-657.
9. Biederman J,. 1998. Attention-deficit/hyperactivity disorder: a life-span perspective. J Clin Psychiatry 59 (Suppl 7): 4-16.
10. Cantwell DP,. 1998. ADHD through the life span: the role of bupropion in treatment. J Clin Psychiatry 59 (Suppl 4): 92-94.
11. Casat CD, Pleasants DZ, Van Wyck Fleet J,. 1987. A double-blind trial of bupropion in children with attention deficit disorder. Psychopharmacol Bull 23: 120-122.
12. Conners CK, Casat CD, Gualtieri CT, et al,. 1996. Bupropion hydrochloride in attention deficit disorder with hyperactivity. J Am Acad Child Adolesc Psychiatry 35: 1314-1321.
13. Daviss WB, Bentivoglio P, Racusin R, Brown KM, Bostic JQ, Wiley L,. 2001. Bupropion sustained release in adolescents with comorbid attention-deficit/ hyperactivity disorder and depression. J Am Acad Child Adolesc Psychiatry 40: 307-314.
14. Dupaul GJ, Power TJ, Anastopoulos AD, Reid R,. 1998. ADHD Rating Scale-IV: Checklists, norms, and clinical interpretation. Guilford Press: New York.
15. Ghanizadeh A, Mohammadi MR, Yazdanshenas A,. 2006. Psychometric properties of the Farsi translation of the Kiddie Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version. BMC Psychiatry 6: 10.
16. Kahbazi M, Ghoreishi A, Rahiminejad F, Mohammadi MR, Kamalipour A, Akhondzadeh S,. 2009. A randomized, double-blind and placebo-controlled trial of modafinil in children and adolescents with attention deficit and hyperactivity disorder. Psychiatry Res 168: 234-237.
17. Kuperman S, Perry PJ, Gaffney GR, et al,. 2001. Bupropion SR vs. methylphenidate vs. placebo for attention deficit hyperactivity disorder in adults. Ann Clin Psychiatry 13: 129-134.
18. Lee MS, Yang JW, Ko YH, et al,. 2008. Effects of methylphenidate and bupropion on DHEA-S and cortisol plasma levels in attention-deficit hyperactivity disorder. Child Psychiatry Hum Dev 39: 201-209.
19. Levin FR, Evans SM, Mcdowell DM, Brooks DJ, Nunes E,. 2002. Bupropion treatment for cocaine abuse and adult attention-deficit/hyperactivity disorder. J Addict Dis 21: 1-16.
20. Levin FR, Evans SM, Brooks DJ, Kalbag AS, Garawi F, Nunes EV,. 2006. Treatment of methadone-maintained patients with adult ADHD: double-blind comparison of methylphenidate, bupropion and placebo. Drug Alcohol Depend 81: 137-148.
21. Maneeton N, Maneeton B, Srisurapanont M, Martin SD,. 2011. Bupropion for adults with attention-deficit hyperactivity disorder: meta-analysis of randomized, placebo-controlled trials. Psychiatry Clin Neurosci 65: 611-617.
22. Mohammadi MR, Akhondzadeh S,. 2007. Pharmacotherapy of attention-deficit/hyperactivity disorder: nonstimulant medication approaches. Expert Rev Neurother 7: 195-201.
23. Mohammadi M, Akhondzadeh S,. 2011. Advances and considerations in attention-deficit/hyperactivity disorder pharmacotherapy. Acta Med Iran 49: 487-498.
24. Mohammadi MR, Kazemi MR, Zia E, Rezazadeh SA, Tabrizi M, Akhondzadeh S,. 2010. Amantadine versus methylphenidate in children and adolescents with attention deficit/hyperactivity disorder: a randomized, double-blind trial. Hum Psychopharmacol 25: 560-565.
25. Monuteaux MC, Spencer TJ, Faraone SV, Wilson AM, Biederman J,. 2007. A randomized, placebo-controlled clinical trial of bupropion for the prevention of smoking in children and adolescents with attention-deficit/hyperactivity disorder. J Clin Psychiatry 68: 1094-1101.
26. Olvera RL, Pliszka SR, Luh J, Tatum R,. 1996. An open trial of venlafaxine in the treatment of attention-deficit/hyperactivity disorder in children and adolescents. J Child Adolesc Psychopharmacol 6: 241-250.
27. Paul M,. 2008. Bupropion. In xPharm: The Comprehensive Pharmacology Reference, Editors-in-chief:, Enna sj, David BB, (eds). Elsevier: New York.
28. Pliszka SR,. 2003. Non-stimulant treatment of attention-deficit/ hyperactivity disorder. CNS Spectr 8: 253-258.
29. Polanczyk G, De Lima MS, Horta BL, Biederman J, Rohde LA,. 2007. The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry 164: 942-948.
30. Reimherr FW, Hedges DW, Strong RE, Marchant BK, Williams ED,. 2005. Bupropion SR in adults with ADHD: a short-term, placebo-controlled trial. Neuropsychiatr Dis Treat 1: 245-251.
31. Riggs PD, Leon SL, Mikulich SK, Pottle LC,. 1998. An open trial of bupropion for ADHD in adolescents with substance use disorders and conduct disorder. J Am Acad Child Adolesc Psychiatry 37: 1271-1278.
32. Schachter HM, Pham B, King J, Langford S, Moher D,. 2001. How efficacious and safe is short-acting methylphenidate for the treatment of attention-deficit disorder in children and adolescents? A meta-analysis. CMAJ 165: 1475-1488.
33. Solhkhah R, Wilens TE, Daly J, Prince JB, Van Patten SL, Biederman J,. 2005. Bupropion SR for the treatment of substance-abusing outpatient adolescents with attention-deficit/hyperactivity disorder and mood disorders. J Child Adolesc Psychopharmacol 15: 777-786.
34. Spencer T, Biederman J, Steingard R, Wilens T,. 1993. Bupropion exacerbates tics in children with attention-deficit hyperactivity disorder and Tourette's syndrome. J Am Acad Child Adolesc Psychiatry 32: 211-214.
35. Spencer T, Biederman J, Wilens T,. 2004. Nonstimulant treatment of adult attention-deficit/hyperactivity disorder. Psychiatr Clin North Am 27: 373-383.
36. Upadhyaya HP, Brady KT, Wang W,. 2004. Bupropion SR in adolescents with comorbid ADHD and nicotine dependence: a pilot study. J Am Acad Child Adolesc Psychiatry 43: 199-205.
37. Waxmonsky JG,. 2005. Nonstimulant therapies for attention-deficit hyperactivity disorder (ADHD) in children and adults. Essent Psychopharmacol 6: 262-276.
38. Wilens TE, Spencer TJ, Biederman J, et al,. 2001. A controlled clinical trial of bupropion for attention deficit hyperactivity disorder in adults. Am J Psychiatry 158: 282-288.